Should You Buy GlaxoSmithKline plc Or AstraZeneca plc?

After releasing disappointing results today, is GlaxoSmithKline plc (LON: GSK) still a better buy than AstraZeneca plc (LON: AZN)?

| More on:

The content of this article was relevant at the time of publishing. Circumstances change continuously and caution should therefore be exercised when relying upon any content contained within this article.

You’re reading a free article with opinions that may differ from The Motley Fool’s Premium Investing Services. Become a Motley Fool member today to get instant access to our top analyst recommendations, in-depth research, investing resources, and more. Learn More.

GlaxoSmithKlineIt’s been a disappointing year thus far for investors in GlaxoSmithKline (LSE: GSK) (NYSE: GSK.US), with shares in the pharmaceutical company being down 6%. This does not compare favourably to the wider market (the FTSE 100 is up 1%), nor to sector peer, AstraZeneca (LSE: AZN) (NYSE: AZN.US), which is up 23% having benefited from bid approaches from Pfizer.

A Challenging Quarter

Indeed, GlaxoSmithKline’s results released today showed that the company is struggling to come to terms with declining dales for its blockbuster inhaler, Advair. The removal of Advair from the reimbursement list of the US’s biggest prescription manager, Express Scripts, compounded falling sales for its omega 3 medicine, Lovaza, which is experiencing high levels of generic competition. The overall effect of this, as well as ongoing issues with regards to alleged bribery in China, has been a 4% reduction in revenue and a 12% fall in profit (after currency effects are removed).

A Different Story at AstraZeneca?

Meanwhile, sector peer AstraZeneca is also experiencing difficulties at present. Its patent cliff is in full-swing, with earnings for the full year expected to be 15% lower than last year, followed by a further 3% fall next year. This is in contrast to GlaxoSmithKline, which now expects flat earnings this year, with the market forecasting a rise of 9% next year.

However, investors are focused on the longer term for AstraZeneca, with the company’s strategy of acquisition in order to overcome its patent woes proving popular among investors. For GlaxoSmithKline, though, the focus is on a much shorter timeframe and the company’s enviable drugs pipeline is not the key motivator for investors right now when, in fact, it could be argued that it should be. That’s because it will be GlaxoSmithKline’s pipeline that will be the main driver of the company’s future growth.

Looking Ahead

Despite GlaxoSmithKline’s update being disappointing today, it continues to offer better growth prospects, a better valuation and a better yield than AstraZeneca. For instance, GlaxoSmithKline trades on a price to earnings (P/E) ratio of 13.5, while AstraZeneca’s P/E is 17.6. The two companies’ yields, meanwhile, are 5.4% (GlaxoSmithKline) and 3.8% (AstraZeneca), again highlighting that GlaxoSmithKline is the more attractive investment at the present time.

Certainly, the allegations regarding bribery in China are causing a certain amount of share price weakness, as are doubts regarding the loss of patent protection on key, blockbuster drugs. However, GlaxoSmithKline has a strong pipeline, growth potential, a top-notch yield and is trading at a significant discount to a key peer in AstraZeneca. As such, it appears to be a great buy at present with a bright long-term future ahead of it.

Peter Stephens owns shares of AstraZeneca and GlaxoSmithKline. The Motley Fool recommends GlaxoSmithKline.

More on Investing Articles

Female student sitting at the steps and using laptop
Investing Articles

UK stocks: the contrarian choice for 2026

UK stocks aren’t the consensus choice for investors at the moment. But some smart money managers who are looking to…

Read more »

Investing Articles

Down 20% in 2025, shares in this under-the-radar UK defence tech firm could be set for a strong 2026

Cohort shares are down 20% this year, but NATO spending increases could offer UK investors a huge potential opportunity going…

Read more »

Young Caucasian woman with pink her studying from her laptop screen
Investing Articles

New to investing? Here’s Warren Buffett’s strategy for starting from scratch

Warren Buffett says he could find opportunities to earn a 50% annual return in the stock market if he was…

Read more »

Investing Articles

Can the sensational Barclays share price do it all over again in 2026?

Harvey Jones is blown away by what the Barclays share price has been doing lately. Now he looks at whether…

Read more »

Investing Articles

Prediction: in 2026 mega-cheap Diageo shares could turn £10,000 into…

Diageo shares have been burning wealth lately but Harvey Jones says long-suffering investors in the FTSE 100 stock may get…

Read more »

Investing Articles

This overlooked FTSE 100 share massively outperformed Tesla over 5 years!

Tesla has been a great long-term investment, but this lesser-known FTSE 100 company would have been an even better one.

Read more »

A pastel colored growing graph with rising rocket.
Investing Articles

I’m backing these 3 value stocks to the hilt – will they rocket in 2026?

Harvey Jones has bought these three FTSE 100 value stocks on three occasions lately, averaging down every time they fall.…

Read more »

Investing Articles

Can the barnstorming Tesco share price do it all over again in 2026?

Harvey Jones is blown away by just how well the Tesco share price has done lately, and asks whether the…

Read more »