Is the AstraZeneca share price a FTSE 100 bargain?

G A Chester discusses the investment case for FTSE 100 (INDEXFTSE:UKX) giant AstraZeneca plc (LON:AZN) and a small-cap pharma firm with news today.

| More on:

The content of this article was relevant at the time of publishing. Circumstances change continuously and caution should therefore be exercised when relying upon any content contained within this article.

You’re reading a free article with opinions that may differ from The Motley Fool’s Premium Investing Services. Become a Motley Fool member today to get instant access to our top analyst recommendations, in-depth research, investing resources, and more. Learn More.

The AstraZeneca (LSE: AZN) share price has retreated from a high of 6,525p made as recently as 21 March. Currently trading at not much above 6,000p, could this dip be an opportunity to snap up some shares?

Here, I’ll discuss the valuation and prospects of the FTSE 100 giant. I’ll also look at small-cap peer Alliance Pharma (LSE: APH), which released a trading update this morning.

Contrasting business models

Astra and Alliance may be in the same industry, but they have very different business models. The £80bn-cap Footsie group is a traditional, research-led big pharma business, trusting in heavy research investment to unearth its share of blockbuster drugs.

By contrast, £400m-cap AIM-listed Alliance licences or acquires pharmaceutical and consumer healthcare products — it has a portfolio of over 90 — at prices on which it believes it can make a good return.

Growth at a reasonable price

In today’s update ahead of its AGM, Alliance said it continues to trade well, with overall performance in line with expectations. It added: “We look ahead to the remainder of 2019 with confidence.”

City analysts are forecasting earnings per share (EPS) growth of 11% to 5.03p this year (following 12% growth last year). At a share price of 76.5p, this gives a forward price-to-earnings (P/E) ratio of 15.2.

I believe this proven, relatively low-risk business merits the P/E rating, and offers growth at a reasonable price. I think fairly consistent annual double-digit EPS growth is a credible prospect, supplemented by dividend growth from the 1.6p forecast for this year (prospective yield of 2.1%). As such, I rate the stock a ‘buy’.

Return to growth

Meanwhile, AstraZeneca has struggled for growth for many years, a string of patent expiries on some of its biggest blockbuster drugs taking a heavy toll. Revenues from these products fell off a cliff when exposed to competition from cheap generics.

It’s taken a long time for the company to rebuild its pipeline, and for new products with blockbuster potential to come through. However, that pipeline is now looking strong, and revenues and profits are forecast to start growing again.

The company has guided for core EPS of between $3.50 and $3.70 this year which, at the midpoint, would be 4% ahead of last year. At the current share price of 6,030p, and at current exchange rates, the midpoint $3.60 EPS equates to 285p and a P/E of 21.2. A running dividend of $2.80 (222p) gives a yield of 3.7%.

Heydays gone for good?

Despite the prospect of a return to growth in coming years, I reckon Astra’s P/E of 21.2 is far too optimistic. I think the heydays for the big pharma of earlier this century — when companies were making a terrific profit margin and return on capital employed — are gone for good.

There are two principal reasons behind my belief. First, every breakthrough drug sets the bar higher for the next. I think this is manifested in endemic falling returns on R&D investment in the industry. Secondly, as my colleague Stepan Lavrouk recently pointed out, public health bodies, such as the US Food and Drug Administration, are “increasingly seen to favour lower-cost alternatives to some of the more expensive options.”

For these reasons, I’m inclined to avoid Astra on its current P/E. There’s growth to come, for sure, but I don’t think it’s growth at a reasonable price right now.

G A Chester has no position in any of the shares mentioned. The Motley Fool UK has recommended Alliance Pharma and AstraZeneca. Views expressed on the companies mentioned in this article are those of the writer and therefore may differ from the official recommendations we make in our subscription services such as Share Advisor, Hidden Winners and Pro. Here at The Motley Fool we believe that considering a diverse range of insights makes us better investors.

More on Investing Articles

Female student sitting at the steps and using laptop
Investing Articles

UK stocks: the contrarian choice for 2026

UK stocks aren’t the consensus choice for investors at the moment. But some smart money managers who are looking to…

Read more »

Investing Articles

Down 20% in 2025, shares in this under-the-radar UK defence tech firm could be set for a strong 2026

Cohort shares are down 20% this year, but NATO spending increases could offer UK investors a huge potential opportunity going…

Read more »

Young Caucasian woman with pink her studying from her laptop screen
Investing Articles

New to investing? Here’s Warren Buffett’s strategy for starting from scratch

Warren Buffett says he could find opportunities to earn a 50% annual return in the stock market if he was…

Read more »

Investing Articles

Can the sensational Barclays share price do it all over again in 2026?

Harvey Jones is blown away by what the Barclays share price has been doing lately. Now he looks at whether…

Read more »

Investing Articles

Prediction: in 2026 mega-cheap Diageo shares could turn £10,000 into…

Diageo shares have been burning wealth lately but Harvey Jones says long-suffering investors in the FTSE 100 stock may get…

Read more »

Investing Articles

This overlooked FTSE 100 share massively outperformed Tesla over 5 years!

Tesla has been a great long-term investment, but this lesser-known FTSE 100 company would have been an even better one.

Read more »

A pastel colored growing graph with rising rocket.
Investing Articles

I’m backing these 3 value stocks to the hilt – will they rocket in 2026?

Harvey Jones has bought these three FTSE 100 value stocks on three occasions lately, averaging down every time they fall.…

Read more »

Investing Articles

Can the barnstorming Tesco share price do it all over again in 2026?

Harvey Jones is blown away by just how well the Tesco share price has done lately, and asks whether the…

Read more »