Should You Buy GlaxoSmithKline plc Or AstraZeneca plc?

After releasing disappointing results today, is GlaxoSmithKline plc (LON: GSK) still a better buy than AstraZeneca plc (LON: AZN)?

| More on:

The content of this article was relevant at the time of publishing. Circumstances change continuously and caution should therefore be exercised when relying upon any content contained within this article.

You’re reading a free article with opinions that may differ from The Motley Fool’s Premium Investing Services. Become a Motley Fool member today to get instant access to our top analyst recommendations, in-depth research, investing resources, and more. Learn More.

GlaxoSmithKlineIt’s been a disappointing year thus far for investors in GlaxoSmithKline (LSE: GSK) (NYSE: GSK.US), with shares in the pharmaceutical company being down 6%. This does not compare favourably to the wider market (the FTSE 100 is up 1%), nor to sector peer, AstraZeneca (LSE: AZN) (NYSE: AZN.US), which is up 23% having benefited from bid approaches from Pfizer.

A Challenging Quarter

Indeed, GlaxoSmithKline’s results released today showed that the company is struggling to come to terms with declining dales for its blockbuster inhaler, Advair. The removal of Advair from the reimbursement list of the US’s biggest prescription manager, Express Scripts, compounded falling sales for its omega 3 medicine, Lovaza, which is experiencing high levels of generic competition. The overall effect of this, as well as ongoing issues with regards to alleged bribery in China, has been a 4% reduction in revenue and a 12% fall in profit (after currency effects are removed).

A Different Story at AstraZeneca?

Meanwhile, sector peer AstraZeneca is also experiencing difficulties at present. Its patent cliff is in full-swing, with earnings for the full year expected to be 15% lower than last year, followed by a further 3% fall next year. This is in contrast to GlaxoSmithKline, which now expects flat earnings this year, with the market forecasting a rise of 9% next year.

However, investors are focused on the longer term for AstraZeneca, with the company’s strategy of acquisition in order to overcome its patent woes proving popular among investors. For GlaxoSmithKline, though, the focus is on a much shorter timeframe and the company’s enviable drugs pipeline is not the key motivator for investors right now when, in fact, it could be argued that it should be. That’s because it will be GlaxoSmithKline’s pipeline that will be the main driver of the company’s future growth.

Looking Ahead

Despite GlaxoSmithKline’s update being disappointing today, it continues to offer better growth prospects, a better valuation and a better yield than AstraZeneca. For instance, GlaxoSmithKline trades on a price to earnings (P/E) ratio of 13.5, while AstraZeneca’s P/E is 17.6. The two companies’ yields, meanwhile, are 5.4% (GlaxoSmithKline) and 3.8% (AstraZeneca), again highlighting that GlaxoSmithKline is the more attractive investment at the present time.

Certainly, the allegations regarding bribery in China are causing a certain amount of share price weakness, as are doubts regarding the loss of patent protection on key, blockbuster drugs. However, GlaxoSmithKline has a strong pipeline, growth potential, a top-notch yield and is trading at a significant discount to a key peer in AstraZeneca. As such, it appears to be a great buy at present with a bright long-term future ahead of it.

Peter Stephens owns shares of AstraZeneca and GlaxoSmithKline. The Motley Fool recommends GlaxoSmithKline.

More on Investing Articles

Two white male workmen working on site at an oil rig
Dividend Shares

More oil wobbles as the BP share price dives 7% in a day!

The BP share price has been wildly volatile in 2026, bouncing around with each new move in the US-Iran war.…

Read more »

British bank notes and coins
Investing Articles

Meet the 9.6%-yielding income share that could keep growing its payout!

This income share yields close to 10% -- and has grown its dividend per share year after year for well…

Read more »

Fireworks display in the shape of willow at Newcastle, Co. Down , Northern Ireland at Halloween.
Investing Articles

When will Barclays shares hit £10?

Barclays shares were close to £1 not so long ago, but could they do the unthinkable and make it to…

Read more »

Picture of an easyJet plane taking off.
Investing Articles

easyJet shares have bounced back before. On a P/E ratio of 6, could they do it again?

Our writer thinks easyJet shares could turn out to be a terrific bargain from a long-term perspective. So is he…

Read more »

Stack of British pound coins falling on list of share prices
Investing Articles

Could National Grid shares offer me a dividend that won’t be hurt by inflation?

National Grid aims to inflation-proof its dividend per share with a policy of annual rises that match inflation. Is our…

Read more »

Young female business analyst looking at a graph chart while working from home
Investing Articles

Here’s what happened to £1,000 invested in the past 2 stock market crashes

History may not repeat itself, but our writer reckons there are lessons to be learned from what recent stock market…

Read more »

Young Caucasian woman at the street withdrawing money at the ATM
Investing Articles

Here’s how the HSBC share price reached an all-time high… and what might be next

HSBC’s record share price reflects a strong rebound in profits and investor confidence, but future gains may be bumpier from…

Read more »

UK coloured flags waving above large crowd on a stadium sport match.
Investing Articles

Investors tempted by beaten-down Diageo shares should mark 6 May on their calendars now

Diageo is a top British blue-chip but its shares have come under fire in recent years. Harvey Jones hopes investors…

Read more »