Novacyt or AstraZeneca: which biotech stock should I buy?

Novacyt and AstraZeneca are two biotech stocks working in the realms of fighting the Covid-19 pandemic. Are either good long-term investments?

| More on:

The content of this article was relevant at the time of publishing. Circumstances change continuously and caution should therefore be exercised when relying upon any content contained within this article.

You’re reading a free article with opinions that may differ from The Motley Fool’s Premium Investing Services. Become a Motley Fool member today to get instant access to our top analyst recommendations, in-depth research, investing resources, and more. Learn More.

FTSE Aim-listed stock Novacyt SA (LSE:NCYT), has seen its share price plunge 35% year-to-date. It had fallen further but has since rebounded. The Anglo-French biotech stock has a £260m market cap, earnings per share (EPS) are negative, and the NCYT share price is down 56% from its 52-week high.

Nevertheless, its share price is rising in recent trading sessions after a positive release on its latest Covid-19 tests. Its new product line includes lateral flow antibody detection and new variant tests. While this is promising, a very big red flag over the company is its recent loss of a lucrative NHS contract. Without this, it doesn’t look nearly as enticing as it did last year.

This is undoubtedly a risky, volatile stock to own. Competition is rife in the Covid-19 testing sector, and its share price has already seen wide speculation by the market. Therefore, I’m not tempted to buy shares in this biotech stock. I prefer well-established pharma companies such as AstraZeneca (LSE:AZN) or Hikma Pharmaceuticals.

Will the AstraZeneca share price bounce?

FTSE 100 pharma giant AstraZeneca is itself facing a host of troubles. As it embarked on producing a Covid-19 vaccine last year, its future looked bright. Working alongside the UK’s prestigious Oxford university, it received glowing media coverage with an early study showing a strong immune response in older adults. Not needing to be stored at extreme temperatures proved a logistical advantage over Pfizer.

But since then, things have rapidly gone downhill. There were production delays and problems with distribution. Recently, concerns that the vaccine leads to blood clots have caused several European countries to halt its use. And there are reports the vaccine doesn’t appear to be as effective as first believed. It may also face litigation costs in a trial with the EU for failed vaccine deliveries.

The AstraZeneca share price also fell in December after it announced its acquisition of US biotech stock Alexion, which shareholders deemed too expensive. Alexion develops life-changing therapies for people living with rare disorders. This unique perspective will enhance AstraZeneca’s portfolio and could complement its research in other areas.  

The AZN share price ended 2020 down 4%. Year-to-date it’s up 2%, despite considerable volatility. It has a price-to-earnings ratio of 43, EPS are 175p, and its dividend yield is 2.6%.

A biotech stock with multiple revenue streams

While the Astra-Oxford Covid-19 vaccine commands headlines, I think the company actually has plenty else keeping shareholders reassured.

This week the company announced its phase 3 trial for a respiratory drug is progressing successfully, showing potential immunisation against RSV in the general infant population. RSV is a common pathogen that causes bronchiolitis and pneumonia in infants globally.

It also has an early stage lung cancer drug in the pipeline already approved in China. This drug called Tagrisso has also been recommended for marketing authorisation in the EU.

AZN is operating in key areas of medical research including respiratory, cancer, and heart disease. The fight against each of them continues, and AstraZeneca’s expertise will be in demand for many years to come. That’s why I feel bullish on AstraZeneca’s long-term outlook and would happily add AZN shares to my Stocks and Shares ISA.

Kirsteen has no position in any of the shares mentioned. The Motley Fool UK has recommended Hikma Pharmaceuticals. Views expressed on the companies mentioned in this article are those of the writer and therefore may differ from the official recommendations we make in our subscription services such as Share Advisor, Hidden Winners and Pro. Here at The Motley Fool we believe that considering a diverse range of insights makes us better investors.

More on Investing Articles

Investing Articles

The key number that could signal a recovery for the Greggs share price in 2026

The Greggs share price has crashed in 2025, but is the company facing serious long-term challenges or are its issues…

Read more »

Rolls-Royce's Pearl 10X engine series
Investing Articles

Can the Rolls-Royce share price hit £16 in 2026? Here’s what the experts think

The Rolls-Royce share price has been unstoppable. Can AI data centres and higher defence spending keep the momentum going in…

Read more »

Businessman with tablet, waiting at the train station platform
Investing Articles

Up 150% in 5 years! What’s going on with the Lloyds share price?

The Lloyds share price has had a strong five years. Our writer sees reasons to think it could go even…

Read more »

Investing Articles

Where will Rolls-Royce shares go in 2026? Here’s what the experts say!

Rolls-Royce shares delivered a tremendous return for investors in 2025. Analysts expect next year to be positive, but slower.

Read more »

Emma Raducanu for Vodafone billboard animation at Piccadilly Circus, London
Investing Articles

Up 40% this year, can the Vodafone share price keep going?

Vodafone shareholders have been rewarded this year with a dividend increase on top of share price growth. Our writer weighs…

Read more »

Buffett at the BRK AGM
Investing Articles

Here’s why I like Tesco shares, but won’t be buying any!

Drawing inspiration from famed investor Warren Buffett's approach, our writer explains why Tesco shares aren't on his shopping list.

Read more »

Investing For Beginners

If the HSBC share price can clear these hurdles, it could fly in 2026

After a fantastic year, Jon Smith points out some of the potential road bumps for the HSBC share price, including…

Read more »

Investing Articles

I’m thrilled I bought Rolls-Royce shares in 2023. Will I buy more in 2026?

Rolls-Royce has become a superior company, with rising profits, buybacks, and shares now paying a dividend. So is the FTSE…

Read more »