Is ReNeuron Group plc a better buy than AstraZeneca plc?

Should you ditch AstraZeneca plc (LON: AZN) in favour of ReNeuron Group plc (LON: RENE)?

| More on:

The content of this article was relevant at the time of publishing. Circumstances change continuously and caution should therefore be exercised when relying upon any content contained within this article.

When investing, your capital is at risk. The value of your investments can go down as well as up and you may get back less than you put in.

Read More

The content of this article is provided for information purposes only and is not intended to be, nor does it constitute, any form of personal advice. Investments in a currency other than sterling are exposed to currency exchange risk. Currency exchange rates are constantly changing, which may affect the value of the investment in sterling terms. You could lose money in sterling even if the stock price rises in the currency of origin. Stocks listed on overseas exchanges may be subject to additional dealing and exchange rate charges, and may have other tax implications, and may not provide the same, or any, regulatory protection as in the UK.

You’re reading a free article with opinions that may differ from The Motley Fool’s Premium Investing Services. Become a Motley Fool member today to get instant access to our top analyst recommendations, in-depth research, investing resources, and more. Learn More.

Shares in healthcare company ReNeuron (LSE: RENE) have risen by over 4% today after it released an encouraging trading update. It shows that the company is making good progress with its strategy, which is providing tangible results according to a further announcement made by the company today. Does this mean that it worth buying ahead of larger healthcare peer AstraZeneca (LSE: AZN)?

Upbeat progress

ReNeuron’s update includes information regarding the outcome of a Phase II clinical trial for its CTX cell therapy candidate for stroke disability. It showed positive results, with three of the 21 patients reporting a two-point or more increase in a grasping and lift test at three months post-treatment.

This was ahead of the target of two patients achieving that goal. The company will now continue with an application in the US and Europe for a pivotal clinical trial in patients living with disability post-stroke.

This is a significant milestone for the company and shows that its treatment has the potential to meet at least some of the high demand for treatments for chronic stroke disability. Clearly, there’s still some way to go in this endeavour, but it’s moving in the right direction.

Furthermore, ReNeuron announced positive news regarding the Phase I/II clinical trial of its hRPC cell therapy candidate. Its therapeutic programmes remain well-funded and it’s on target to meet its medium-term milestones at the present time.

Future potential

Clearly, ReNeuron has a bright long-term future. However, it remains a relatively small business, which is reliant on a smaller number of potential treatments than a sector peer such as AstraZeneca. Its larger peer has a more diversified pipeline so that if a potential treatment disappoints at a clinical trial, the company’s long-term future isn’t staked on it. As a result of this, AstraZeneca offers a much lower risk profile than ReNeuron.

Furthermore, AstraZeneca is on the cusp of improved financial performance following a major acquisition programme. It has been able to leverage a sound balance sheet and strong cash flow to make multiple purchases in recent years. This will see the company eventually replace the former blockbuster drugs that are now under threat from generics due to a loss of patents.

So, while AstraZeneca is expected to record a fall in profitability over the next couple of years, its longer-term future is much brighter. And with it trading on a price-to-earnings (P/E) ratio of 12, it offers excellent value for money.

As such, it offers lower risk than ReNeuron, as well as the potential for high rewards in the long run. Certainly, ReNeuron may prove to be a sound buy for less risk-averse investors and its share price is likely to move higher following today’s positive update. But for risk-averse investors, AstraZeneca remains the more appealing choice.

Should you invest, the value of your investment may rise or fall and your capital is at risk. Before investing, your individual circumstances should be assessed. Consider taking independent financial advice.

Peter Stephens owns shares of AstraZeneca. The Motley Fool UK has recommended AstraZeneca. We Fools don't all hold the same opinions, but we all believe that considering a diverse range of insights makes us better investors.

More on Investing Articles

Young female business analyst looking at a graph chart while working from home
Investing Articles

Is Avon Protection the best stock to buy in the FTSE All-Share index right now?

Here’s a stock I’m holding for recovery and growth from the FTSE All-Share index. Can it be crowned as the…

Read more »

Investing Articles

Down 8.5% this month, is the Aviva share price too attractive to ignore?

It’s time to look into Aviva and the insurance sector while the share price is pulling back from year-to-date highs.

Read more »

Investing Articles

Here’s where I see Vodafone’s share price ending 2024

Valued at just twice its earnings, is the Vodafone share price a bargain or value trap? Our writer explores where…

Read more »

Businesswoman analyses profitability of working company with digital virtual screen
Investing Articles

The Darktrace share price jumped 20% today. Here’s why!

After the Darktrace share price leapt by a fifth in early trading, our writer explains why -- and what it…

Read more »

Dividend Shares

850 shares in this dividend giant could make me £1.1k in passive income

Jon Smith flags up one dividend stock for passive income that has outperformed its sector over the course of the…

Read more »

Investing Articles

Unilever shares are flying! Time to buy at a 21% ‘discount’?

Unilever shares have been racing higher this week after a one-two punch of news from the company. Here’s whether I…

Read more »

artificial intelligence investing algorithms
Market Movers

The Microsoft share price surges after results. Is this the best AI stock to buy?

Jon Smith flags up the jump in the Microsoft share price after the latest results showed strong demand for AI…

Read more »

Google office headquarters
Investing Articles

A dividend announcement sends the Alphabet share price soaring. Here’s what investors need to know

As the Alphabet share price surges on the announcement of a dividend, Stephen Wright outlines what investors should really be…

Read more »