Share your opinion and earn yourself a free Motley Fool premium report!

We are looking for Fools to join a 75 minute online independent market research forum on 15th / 16th December.

To find out more and express your interest please click here

Down 83%! This FTSE 250 firm could now be a stock market takeover target

After a serious stock market slump, the boss of this FTSE 250 biotech company has reportedly highlighted its takeover exposure.

| More on:

The content of this article was relevant at the time of publishing. Circumstances change continuously and caution should therefore be exercised when relying upon any content contained within this article.

British flag, Big Ben, Houses of Parliament and British flag composition

Image source: Getty Images

You’re reading a free article with opinions that may differ from The Motley Fool’s Premium Investing Services. Become a Motley Fool member today to get instant access to our top analyst recommendations, in-depth research, investing resources, and more. Learn More.

It’s been a torrid few years for shareholders of Oxford Nanopore Technologies (LSE: ONT). Since the biotech company listed on the UK stock market in late 2021, its share price has crashed by more than 80%.

This is sad to see as the FTSE 250 firm’s founders had ambitions to build a homegrown British giant in the healthcare space.

The sharp fall means Oxford Nanopore’s market cap now stands at just under £1bn — hardly the status of a giant!

Acquisition target

For those unfamiliar, Oxford Nanopore’s devices enable gene sequencing on handheld devices. It pioneered nanopore technology, which reads DNA or RNA in real time by detecting electrical changes as molecules pass through tiny pores. 

The stock market slide leaves it open to potential takeover bids, the firm’s co-founder and CEO Gordon Sanghera recently told the Financial Times. Especially as his anti-takeover share — a golden share allowing him to fend off bidders for three years after the IPO — has lapsed.

The FT mentioned that the company might be an attractive target for large US diagnostics specialists like Danaher or Thermo Fisher Scientific. The latter’s market cap is about 158 times larger than Oxford Nanopore’s, so the UK biotech could be a tasty morsel.

I note that analysts’ share price target is currently 174p, which is 67% above the current level. So it’s possible an acquisition could value the company significantly higher than today’s share price of 104p.

Of course, this is all just speculation. And I learned long ago not to invest on the basis of takeover potential alone. Yes, an acquisition may well happen, but it could be some time away and at a lower share price than I’d pay today.

Plenty of risk

To be fair, the company’s revenue growth has been strong, rising from £52m in 2019 to just over £183m last year. And management sees strong double-digit revenue growth continuing. So this is a definite positive here.

However, since 2019, the operating loss has nearly doubled to £152m. Therefore, Oxford Nanopore is still loss-making, and isn’t expecting to reach adjusted EBITDA breakeven till 2027. 

By then, it expects the gross margin to increase to at least 62%, up from 57.5% last year. Yet when the company will be reporting actual bottom-line profits is anyone’s guess at this point. This uncertainty around profitability is why I’ve never bought the stock.

Meanwhile, some analysts are flagging the possibility of slower-than-expected growth moving forward, which is a risk here.

Final thoughts

A switch stateside for Oxford Nanopore was mooted a while back, I seem to remember. But would a US listing really help?

I’m not convinced it would, as the US market has hardly been supportive of loss-making firms recently. For example, shares of rival Pacific Biosciences of California have lost 97% of their value in four years. Illumina stock is down 81% over the same period.

Admittedly, Oxford Nanopore has been growing faster than those two. But the shares that have been doing well across the pond (as here) are all profitable. The desire to buy ‘jam-tomorrow’ stocks while interest rates are high generally remains weak.

Therefore, I still have no desire to invest in the shares today.

Ben McPoland has no position in any of the shares mentioned. The Motley Fool UK has no position in any of the shares mentioned. Views expressed on the companies mentioned in this article are those of the writer and therefore may differ from the official recommendations we make in our subscription services such as Share Advisor, Hidden Winners and Pro. Here at The Motley Fool we believe that considering a diverse range of insights makes us better investors.

More on Investing Articles

Thoughtful man using his phone while riding on a train and looking through the window
Investing Articles

Here’s how much passive income someone could earn maxing out their ISA allowance for 5 years

Christopher Ruane considers how someone might spend a few years building up their Stocks and Shares ISA to try and…

Read more »

Man putting his card into an ATM machine while his son sits in a stroller beside him.
Investing Articles

Was I wrong about Barclays shares, up 196%?

Our writer has watched Barclays shares nearly triple in five years, but stayed on the sidelines. Is he now ready…

Read more »

Wall Street sign in New York City
Investing Articles

Up 17% in 2025, can the S&P 500 power on into 2026?

Why has the S&P 500 done so well this year against a backdrop of multiple challenges? Our writer explains --…

Read more »

National Grid engineers at a substation
Investing Articles

National Grid shares are up 19% in 2025. Why?

National Grid shares have risen by almost a fifth this year. So much for it being a sleepy utility! Should…

Read more »

Road 2025 to 2032 new year direction concept
Investing Articles

Here are the potential dividend earnings from buying 1,000 Aviva shares for the next decade

Aviva has a juicy dividend -- but what might come next? Our writer digs into what the coming decade could…

Read more »

Person holding magnifying glass over important document, reading the small print
Investing Articles

Just released: our top 3 small-cap stocks to consider buying in December [PREMIUM PICKS]

Small-cap shares tend to be more volatile than larger companies, so we suggest investors should look to build up a…

Read more »

This way, That way, The other way - pointing in different directions
Investing Articles

Is the unloved Aston Martin share price about to do a Rolls-Royce?

The Aston Martin share price has inflicted a world of pain on Harvey Jones, but he isn't giving up hope…

Read more »

Surprised Black girl holding teddy bear toy on Christmas
Investing Articles

How much do you need in a Stocks and Shares ISA to raise 1.7 children?

After discovering the cost of raising a child, James Beard explains why he thinks a Stocks and Shares ISA is…

Read more »