If I could only buy 1 FTSE 100 stock, I’d put 100% of my money into this one

Investing my entire portfolio in a single FTSE 100 stock is a very risky strategy, but if I had to pick one I’d choose the largest company in the index.

| More on:

The content of this article was relevant at the time of publishing. Circumstances change continuously and caution should therefore be exercised when relying upon any content contained within this article.

Arrow symbol glowing amid black arrow symbols on black background.

Image source: Getty Images

You’re reading a free article with opinions that may differ from The Motley Fool’s Premium Investing Services. Become a Motley Fool member today to get instant access to our top analyst recommendations, in-depth research, investing resources, and more. Learn More.

I don’t plan to rebalance my stock market portfolio into a single FTSE 100 stock. That’s because I prefer to diversify my investments across different companies and sectors, managing my risk exposure in the process.

Nonetheless, not all shares in the UK’s blue-chip benchmark are equal. I believe some Footsie companies have brighter prospects than others. Accordingly, if I had to choose a single stock to invest in from the index, it would be the Anglo-Swedish pharmaceutical giant AstraZeneca (LSE:AZN).

With a market cap of £182bn, it’s the FTSE 100’s biggest company and I already hold some of its shares. But I think this business has plenty of upside potential for further growth. Here’s why.

Stunning returns

First, it’s worth appreciating the spectacular growth in the AstraZeneca share price. Over the past five years, the stock has climbed nearly 118%. If I’d bought back in mid-2018, my initial investment would have more than doubled in value today.

The upward trajectory has been remarkably consistent too, as the chart above shows. No doubt the company was a beneficiary from the pandemic thanks to its Covid-19 vaccine Vaxzevria, but there’s much more to the business. After all, the stock is close to an all-time high today despite the company’s guidance that it will deliver “minimal” sales of Vaxzevria this year.

A premium pipeline

AstraZeneca’s drugs portfolio is impressive. Spanning a range of diseases, some of its star medicines include lung cancer drug Tagrisso, diabetes drug Farxiga, and leukaemia drug Calquence.

The firm currently has 178 projects in its pipeline, including 14 new molecular entities in its late-stage pipeline. A considerable number of its drugs are currently undergoing phase III clinical trials across its key therapy areas. The company expects to launch 15 new medicines by the end of the decade, some of which could produce more than $1bn in annual revenue.

What’s more, AstraZeneca’s financial results continue to impress. In the first quarter it delivered $10.6bn in revenue. That was flat on a constant currency basis, but once the falling Covid-19 medicine sales are removed from the picture, it represents 15% growth.

This is evidence of depth in the company’s strength across its various divisions. It has indicated full-year revenue will grow by a low-to-mid-single-digit figure.

Risks

However, all stocks face risks, and AstraZeneca is no exception. At present, it has a price-to-earnings ratio of 46.5, which is a considerably higher multiple than the FTSE 100 average of just below 10. The stock certainly isn’t cheap. Any disappointing results from clinical trials could deal a blow to the share price.

In addition, the firm’s balance sheet isn’t flawless either. AstraZeneca’s debt-to-equity ratio is currently 88%. That’s a little high for my liking and I’d like to see the company make some progress in reducing its net debt position.

Why I own AstraZeneca shares

Although there’s a risk the growth opportunities from its pipeline have been priced in, I still think AstraZeneca is a great long-term hold for me. It’s a highly innovative company and CEO Pascal Soriot has done a stellar job over the past decade.

While I wouldn’t invest everything in a single FTSE 100 stock, if it came to it, I’d choose AstraZeneca.

Charlie Carman has positions in AstraZeneca Plc. The Motley Fool UK has no position in any of the shares mentioned. Views expressed on the companies mentioned in this article are those of the writer and therefore may differ from the official recommendations we make in our subscription services such as Share Advisor, Hidden Winners and Pro. Here at The Motley Fool we believe that considering a diverse range of insights makes us better investors.

More on Investing Articles

Older couple walking in park
Investing Articles

How much do I need in my ISA for a £1,000 monthly passive income?

Picking high-income stocks in an ISA can be a route to securing long-term passive income. And here's one with a…

Read more »

Smiling white woman holding iPhone with Airpods in ear
Investing Articles

Prediction: in 12 months the surging Aviva share price and dividend could turn £10,000 into…

Aviva's share price has beaten the broader FTSE 100 over the last year. But can the financial services giant keep…

Read more »

Portrait of elderly man wearing white denim shirt and glasses looking up with hand on chin. Thoughtful senior entrepreneur, studio shot against grey background.
Dividend Shares

I love FTSE 100 dividend shares, but do I buy this FTSE 250 loser?

Over the past year, the UK's FTSE 100 has thrashed the once-mighty US S&P 500 index. With value investing back…

Read more »

Investing Articles

How much do you need in an ISA to target a £2,000 monthly second income?

Harvey Jones crunches the numbers to see how much investors need in a Stocks and Shares ISA to generate a…

Read more »

Passive income text with pin graph chart on business table
Investing Articles

Should investors consider Legal & General shares for passive income?

As many investors are chasing their passive income dreams, our writer Ken Hall evaluates whether Legal & General could help…

Read more »

ISA coins
Investing Articles

How to transform an empty Stocks and Shares ISA into a £15,000 second income

Ben McPoland explains how a UK dividend portfolio can be built from the ground up inside a Stocks and Shares…

Read more »

Investing Articles

I asked ChatGPT if it’s better buy high-yielding UK stocks in an ISA or SIPP and it said…

Harvey Jones loves his SIPP, but he thinks a Stocks and Shares ISA is a pretty good way to invest…

Read more »

DIVIDEND YIELD text written on a notebook with chart
Investing Articles

How much do you need to invest in dividend shares to earn £1,500 a year in passive income?

As the stock market tries to get to grips with AI, could dividend shares offer investors a chance to earn…

Read more »