Which are better buys – FTSE 100 or FTSE 250 stocks?

As a top-down investor, this Fool likes to consider which index, FTSE 100 or FTSE 250, is performing better before taking a deep dive into individual stocks. So what is the verdict?

The content of this article was relevant at the time of publishing. Circumstances change continuously and caution should therefore be exercised when relying upon any content contained within this article.

You’re reading a free article with opinions that may differ from The Motley Fool’s Premium Investing Services. Become a Motley Fool member today to get instant access to our top analyst recommendations, in-depth research, investing resources, and more. Learn More.

September is not turning out to be a good month for the FTSE 100 index. It is down by 0.5% on average compared to August. If the trend continues through the rest of the month, it will only be the third month in 2021 so far when the index value has declined from the month before. The index has risen in the other six months, even as much at 3%, like in April. 

By comparison, the FTSE 250 index has fared better. So far, it has shown a 1.3% increase this month. And if this continues, it will maintain the trend seen all through 2021, save June, when it dropped by 0.3%. Clearly, it looks like the FTSE 250 index is better placed than FTSE 100. 

Why has the FTSE 250 outperformed the FTSE 100 index?

I reckon that this is at least in part because the FTSE 250 stocks are more likely to be UK-centric. These include the likes of UK-focused property stocks Bellway and Derwent London, which are both among the top 20 index constituents by market capitalisation. Since the UK has seen speedy vaccinations in the past months and its growth numbers have also improved, it follows that investors are optimistic about FTSE 250 stocks’ prospects. 

By comparison, FTSE 100 stocks tend to be big multinationals that may have been subject to greater uncertainty in the recent past because of global developments. For instance, banking corporation HSBC’s share price has been sensitive to geopolitical stresses between the US and China on the one hand and China and Hong Kong on the other. Similarly, global oil stocks like BP hinge on the commodity’s price and production changes. And the likes of consumer goods giant Unilever have been in an uncertain place because of uneven recovery in consumer markets. 

Best of both the worlds

But what if a stock could combine the best of both worlds? There are at least some FTSE 100 stocks that come with the benefit of having a large market capitalisation and that are also UK-focused. British utilities, real estate stocks, and supermarkets are examples of three such segments. 

What I’d do now

However, I will refrain from just basing my investment decisions based solely on the index that stocks belong to. One reason is that there are plenty of FTSE 100 multinationals that have performed well this year and could make great long-term investments. An example from my own portfolio is AstraZeneca. 

Another is that the latest macro numbers for the UK do not look good, something I have explored in greater detail in another article today. It appears that these figures may be temporary, but if the trend continues, they could impact FTSE 250 stocks significantly.  

All in all, though, as a top-down investor, I find starting from the big picture helpful in developing my investing strategies. And it clearly suggests that I can find some high-performing stocks among FTSE 250 constituents for my portfolio.

Manika Premsingh owns shares of AstraZeneca and BP. The Motley Fool UK has recommended HSBC Holdings and Unilever. Views expressed on the companies mentioned in this article are those of the writer and therefore may differ from the official recommendations we make in our subscription services such as Share Advisor, Hidden Winners and Pro. Here at The Motley Fool we believe that considering a diverse range of insights makes us better investors.

More on Investing Articles

Middle aged businesswoman using laptop while working from home
Investing For Beginners

I think the best days for Lloyds’ share price are over. Here’s why

Jon Smith explains why Lloyds' share price could come under increasing pressure over the coming year, with factors including a…

Read more »

A graph made of neon tubes in a room
Investing Articles

£5,000 invested in the FTSE 100 at the start of 2025 is now worth…

Looking to invest in the FTSE 100? Royston Wild believes buying individual shares could be the best way to target…

Read more »

Thoughtful man using his phone while riding on a train and looking through the window
Investing Articles

Can the BAE share price do it again in 2026?

The BAE share price has been in good form in 2025. But Paul Summers says a high valuation might be…

Read more »

Investing Articles

Can Rolls-Royce, Babcock, and BAE Systems shares do it all over again in 2026?

Harvey Jones examines whether BAE Systems and other defence-focused FTSE 100 stocks can continue to shoot the lights out in…

Read more »

Investing Articles

7 UK dividend shares yielding over 7% that could thrive if rates fall in 2026

Mark Hartley weighs up the investment benefits of interest rate changes and how they could boost the potential of seven…

Read more »

Investing Articles

These 3 things could make a Stocks and Shares ISA a no-brainer in 2026

The government and the FCA are doing their bit to try to steer investors towards a Stocks and Shares ISA…

Read more »

Businessman using pen drawing line for increasing arrow from 2024 to 2025
Investing Articles

Revealed! The 10 best-performing FTSE 100 shares in 2025

It's been a year of golden gains for the FTSE 100 index, spearheaded by these 10 powerhouse stocks. But can…

Read more »

Snowing on Jubilee Gardens in London at dusk
Investing Articles

Is it time to consider gobbling up these 3 FTSE 100 Christmas turkeys?

Our writer looks at the pros and cons of buying three of the FTSE 100’s (INDEXFTSE:UKX) worst performers over the…

Read more »