My 5 best UK pharma stocks. I’d buy now to get rich in 10 years

The best UK pharma stocks to buy now could make investors rich, Tom Rodgers feels. He picks what he sees as the best from the FTSE 100 to AIM.

The content of this article was relevant at the time of publishing. Circumstances change continuously and caution should therefore be exercised when relying upon any content contained within this article.

You’re reading a free article with opinions that may differ from The Motley Fool’s Premium Investing Services. Become a Motley Fool member today to get instant access to our top analyst recommendations, in-depth research, investing resources, and more. Learn More.

When I think about the best UK pharma stocks that could help me get rich over the next decade, this crop of the finest FTSE 100, FTSE 250 and AIM-listed shares come to mind.

To me these are the best UK pharma stocks because of their unimpeachable economic moats. This is the metric for greatness favoured by the world’s most successful investor Warren Buffett.

These companies achieve this feat through registered trademarks, copyrights and branded products that no other business can legally sell.

So despite high R&D costs, they remain at a long-term advantage to other industries.

Best UK pharma stocks: FTSE 100

GlaxoSmithKline (LSE:GSK) is a world leader in oncology (cancer treatments), HIV and respiratory drugs. And the business is expanding in personal care too. Extending its booming oral health business in India is positive news.

CEO Emma Walmsley declares the pharma giant’s 19p per share dividend like clockwork every quarter. It looks bombproof to me. When the Covid crisis forced FTSE 100 powerhouses like Royal Dutch Shell to cut their dividends, GSK powered on like nothing had happened.

The GSK dividend is 6%, nearly three times larger than the average healthcare stock, on a cheap P/E ratio of 10.

And with annual free cash flow of £5.1bn, there is plenty in the bank to keeping paying out year after year. That makes it a no-brainer buy for me.

My FTSE 250 pick

High-margin prescription veterinary drugs specialist Dechra Pharmaceuticals has me very interested. In the main, its speedy profit growth looks sustainable and the share price has just beaten recent all-time highs too.

Income payouts to Dechra investors are 89% higher than four years ago. And the business raised its dividend again after bumper 2020 full-year profits, which bodes well for the future.

Now for AIM

On AIM, truly great businesses are hard to find, even with the best UK pharma stocks. But picking wisely offers serious multibag possibilities. Novacyt remains a solid choice for me, and seeing its revenues grow 10 times larger year-on-year is of serious interest.

North Carolina-based Polarean Imaging has an unimpeachable economic moat with zero competitors for its non-invasive medical imaging tech. So I’m a fan. But the best UK pharma stock I’m backing to get rich over the next decade is one I already own — Open Orphan (LSE:ORPH).

I’m a huge fan of executive chairman Cathal Friel for stripping out costs and pushing the most profitable parts of the business forward since the 2019 IPO. And he has delivered on every promise to investors to date, lifting revenues with multi-million pound contracts.

Open Orphan has just signed a contract worth up to £40m with the UK government to provide human challenge tests for Covid-19. Clearly these kinds of revenues will be transformational for the small Anglo-Irish contract research business.

And there are a number of other strands of the business that have me excited. One of which is Open Orphan’s 49% ownership of Imutex, a joint venture with London drug manufacturer SEEK Group, which has a candidate for a universal flu vaccine, the holy grail of modern medicine.

The best thing I can say about Open Orphan is that 90% of its revenues have nothing to do with Covid-19. So I can predict it should continue to earn big money well into the future.

TomRodgers has no position in any of the shares mentioned. The Motley Fool UK has recommended GlaxoSmithKline. Views expressed on the companies mentioned in this article are those of the writer and therefore may differ from the official recommendations we make in our subscription services such as Share Advisor, Hidden Winners and Pro. Here at The Motley Fool we believe that considering a diverse range of insights makes us better investors.

More on Investing Articles

Aston Martin DBX - rear pic of trunk
Investing Articles

There are hundreds of shares I’d rather buy than Aston Martin. Here’s why!

Aston Martin shares sell for pennies yet some of its cars can cost millions. So why doesn't this writer see…

Read more »

Young Caucasian man making doubtful face at camera
Investing Articles

3 risks to Greggs shares that could hamper a recovery

Greggs shares have a good dividend, but the price has performed weakly. Is our writer missing something by holding onto…

Read more »

ISA coins
Investing Articles

1 mighty FTSE dividend stock I’m considering for my ISA

A new ISA allowance has Paul Summers searching for strong and stable dividend stocks to add to his portfolio.

Read more »

Rolls-Royce's Pearl 10X engine series
Investing Articles

Are Rolls-Royce shares’ best days behind them?

Rolls-Royce shares have had a stellar few years. So far in 2026, though, they slightly lag the FTSE 100 blue-chip…

Read more »

A rear view of a female in a bright yellow coat walking along the historic street known as The Shambles in York, UK which is a popular tourist destination in this Yorkshire city.
Investing Articles

Buying £20k of Lloyds shares could give me an £851 income this year!

Lloyds has been one of the FTSE 100's hottest dividend growth shares in recent years. But do current risks make…

Read more »

Picturesque Cotswold village of Castle Combe, England
Investing Articles

ISA or SIPP? Some key differences to know

Ever wondered what some of the differences are between investing for retirement in a SIPP and in an ISA? Here…

Read more »

Young woman working at modern office. Technical price graph and indicator, red and green candlestick chart and stock trading computer screen background.
Investing Articles

2 world-class S&P 500 stocks down 11% and 32% to consider buying

Searching for stocks to buy for an ISA in April? Our writher thinks these excellent growth shares are worth a…

Read more »

View over Old Man Of Storr, Isle Of Skye, Scotland
Investing Articles

How much do you need in a Stocks and Shares ISA to aim for an annual income of £39,477?

Harvey Jones shows how ordinary investors can use their Stocks and Shares ISA allowance to build a generous passive income…

Read more »