We have some exciting news to share! The Motley Fool UK has now become an independent, UK-owned company, led by our long-serving UK management team — Mark Rogers, Chris Nials and Heather Adlington. In practical terms, it’s the same team you know, now fully focused on serving our UK readers and members.

Just as importantly, our approach remains unchanged: long-term, jargon-free, and on your side. We’ll be introducing a new name and brand over the coming weeks — we're very excited to share it with you and embark on this new chapter together!

Why You Might Think Of Investing In This FTSE Underdog: AstraZeneca plc

AstraZeneca plc (LON: AZN) could be a contrarian investment opportunity.

| More on:

The content of this article was relevant at the time of publishing. Circumstances change continuously and caution should therefore be exercised when relying upon any content contained within this article.

You’re reading a free article with opinions that may differ from The Motley Fool’s Premium Investing Services. Become a Motley Fool member today to get instant access to our top analyst recommendations, in-depth research, investing resources, and more. Learn More.

Contrarian investors look for stocks that are out of favour with the market. When sentiment is negative then the true value of a stock can be overlooked. I’m trawling the underdogs of the FTSE to identify which of them may not deserve their sub-market PE ratings.

Unloved

AstraZeneca (LSE: AZN) (NYSE: AZN.US) is certainly unloved. At 9.1, its historic P/E is half that of rival GlaxoSmithKline (LSE: GSK) (NYSE: GSK.US). Digital Look shows just 5 out of 35 brokers give it a ‘buy’ rating. And a yield rising year-on-year is a clear sign of a stock supported by its dividend.

Astra’s problem is its well-know patent cliff. Sales dropped by 20% in 2012 as drugs came off-patent, and analysts’ expectations are for continued declines over the next few years. CEO Pascal Soriot has committed Astra to remaining a pure pharma company, and sees its salvation in development of new drugs.  But even he set a modest target of restoring sales in 2018 to their 2011 level.

Safer

I much prefer GSK’s safer, more diversified, strategy. As well as prescription drugs it makes over-the-counter medicines and vaccines. They don’t involve such massive and risky R&D investment.

Indications are that GSK has also overcome its patent cliff, with analysts forecasting an upturn in its drugs revenues. That suggests Astra’s pipeline issues shouldn’t be insurmountable.

Biotech

I have a small holding in Astra. Essentially I see it as a biotech play, but one that pays a fat dividend while it’s developing new drugs.

Astra has targeted three therapeutic areas. This month alone has seen announcements about two biotech company acquisitions and two drugs going to Stage III trials, one for cancer and one for asthma. Global demographics — more, older, wealthier people — underpin demand for whatever the boffins can invent.

Meanwhile Astra’s strong balance sheet, with net gearing of 11% against GSK’s 243%, means the dividend should be safe. Management have relaxed the policy to target two times cover ‘over the investment cycle’ to give them wriggle-room.

Buying opportunity?

Ace investor Neil Woodford is a big fan, with 9% of his Invesco Perpetual funds in each of Astra and GSK. However, either the change of management when he leaves, or investors withdrawing funds from Invesco Perpetual, could see a flow of investment away from Astra.

That’s something I’ll watch. If the shares do weaken in the near term I might add to my holding.  The buy case for Astra needs patience.

 > Tony owns shares in AstraZeneca and GSK but no other shares mentioned in this article. The Motley Fool has recommended shares in GlaxoSmithKline.

More on Investing Articles

Finger clicking a button marked 'Buy' on a keyboard
Investing Articles

I’ve just bought this bargain-priced FTSE 100 bank and it’s not Barclays or Lloyds

Harvey Jones was waiting for the right time to increase his exposure to a FTSE 100 banking stock, and this…

Read more »

Close-up image depicting a woman in her 70s taking British bank notes from her colourful leather wallet.
Investing For Beginners

This value stock could turn £2k into £2,860 this year

Jon Smith points out a value stock that has been hit hard by the Middle East conflict, but he thinks…

Read more »

Runner standing at the starting point with 2025 year for starting in new year 2025 to achieve business planing and success concept.
Value Shares

Thank goodness I didn’t buy Greggs shares in 2025

Greggs was a very popular stock in the early days of 2025. Our author takes a look at his decision…

Read more »

Renewable energies concept collage
Investing Articles

Legal & General shares: still seen as a dividend stock — but that may be outdated

Andrew Mackie looks past the high yield in Legal & General shares to question whether the market is missing its…

Read more »

Concept of two young professional men looking at a screen in a technological data centre
Investing Articles

13,000 more reasons why I’m avoiding IAG shares!

International Consolidated Airlines (IAG) shares are rallying again. But Royston Wild explains why he's still avoiding the volatile FTSE 100…

Read more »

Two mid adult women enjoying a friends reunion city break for the weekend in Newcastle upon Tyne, England.
Investing Articles

This FTSE 250 stock fell by over 3% after solid earnings. Should investors consider buying it?

Trainline’s share price fell this morning, even after publishing solid results for FY26. Should investors consider scooping up some of…

Read more »

Road trip. Father and son travelling together by car
Investing Articles

£10,007 invested in Aston Martin shares on 1 April is now worth…

Aston Martin shares have suddenly started moving upwards, going from 36p to 46p. Is this FTSE 250 stock ready to…

Read more »

The flag of the United States of America flying in front of the Capitol building
Investing Articles

Why NOW could be the best time to find stocks to buy!

I'm looking for more stocks to buy for my ISA and SIPPs. But it's possible some shares could be better…

Read more »