Down 51% in 2024, is this UK growth stock a buy for my Stocks and Shares ISA?

Ben McPoland considers Oxford Nanopore Technologies (LSE:ONT), a UK growth stock that has plunged over 80% since going public in 2021.

| More on:
Engineer Project Manager Talks With Scientist working on Computer

Image source: Getty Images

When investing, your capital is at risk. The value of your investments can go down as well as up and you may get back less than you put in.

Read More

The content of this article is provided for information purposes only and is not intended to be, nor does it constitute, any form of personal advice. Investments in a currency other than sterling are exposed to currency exchange risk. Currency exchange rates are constantly changing, which may affect the value of the investment in sterling terms. You could lose money in sterling even if the stock price rises in the currency of origin. Stocks listed on overseas exchanges may be subject to additional dealing and exchange rate charges, and may have other tax implications, and may not provide the same, or any, regulatory protection as in the UK.

You’re reading a free article with opinions that may differ from The Motley Fool’s Premium Investing Services. Become a Motley Fool member today to get instant access to our top analyst recommendations, in-depth research, investing resources, and more. Learn More.

Oxford Nanopore Technologies (LSE: ONT) is a growth stock I’ve considered a couple of times for my Stocks and Shares ISA. One of my sticking points though has been its high valuation.

But now the share price has fallen around 51% in 2024, I’m taking another look.

Innovative tech

The company has developed the world’s only nanopore DNA and RNA sequencing platform. This involves passing genetic material through tiny holes called nanopores (hence the firm’s name).

As the substance passes through these, it produces electrical signals that are used to decipher the sequence of DNA and RNA. And this method can result in real-time data for rapid insights.

Its portable MinION device is significantly smaller than traditional sequencing machines, offering greater flexibility. Researchers can use them in remote locations, thereby expanding the firm’s total addressable market.

Strong growth

In 2023, underlying life science research tools revenue grew 39% year on year to £170m, excluding legacy Covid-related contracts. Its active customer accounts increased 11% to over 7,600.

This is important because 74% of its revenue came from consumables last year. In other words, it makes most of its money providing supplies after it has sold a device — that’s a ‘razor-and-blades’ business model.

I like this model as it can result in serious profits. However, not for Oxford Nanopore… yet. It reported a £154.5m total loss for the year (much wider than 2022’s £91m loss).

Moreover, it moved its adjusted EBITDA breakeven target from 2026 to the end of 2027. This has likely weakened investor sentiment.

Looking ahead though, management is guiding for 20%-30% underlying revenue growth this year. And greater than 30% in the medium term. Therefore, the growth story is intact here.

Comparing stocks

The performance of two of its rivals hasn’t been much better recently. Shares of Pacific Biosciences of California are down 87% in the last year, while Illumina has shed over 40% of its value.

Created at TradingView

These competitors aren’t expecting much (if any) top-line growth in 2024, which makes Oxford Nanopore’s forecast growth appear even more impressive.

Looking at the price-to-sales (P/S) ratio though, the stock is more expensive (6.19) than these US peers.

Created at TradingView

That said, the forward-looking P/S multiple for 2024 drops to 4.9, which is more attractive.

Vultures circling

Unfortunately, investors today have little patience for firms with sales but only possible future profits. They want reliable profits now, and the business isn’t about to deliver this, so there’s a risk the shares drift even lower.

In this scenario, I think the company could become an acquisition target. It has world-class technology and a growing market opportunity.

We’ve just seen UK cybersecurity firm Darktrace snapped up. So we know private equity vultures are hovering.

Should I buy some shares?

I’ve had my fingers burnt lately investing in Moderna and Ginkgo Bioworks. They’re down between 30% and 50% so far for me. So I don’t have the stomach to invest in yet another loss-making healthcare stock.

However, if this wasn’t the case, I’d consider Oxford Nanopore stock after its 51% drop. It’s seeing increasing adoption of its devices across various research areas, while the market cap is just £833m.

The shares could rebound strongly if market sentiment changes or a bidder emerges — not that I’d ever buy purely on takeover speculation.

Should you invest, the value of your investment may rise or fall and your capital is at risk. Before investing, your individual circumstances should be assessed. Consider taking independent financial advice.

Ben McPoland has positions in Ginkgo Bioworks and Moderna. The Motley Fool UK has no position in any of the shares mentioned. Views expressed on the companies mentioned in this article are those of the writer and therefore may differ from the official recommendations we make in our subscription services such as Share Advisor, Hidden Winners and Pro. Here at The Motley Fool we believe that considering a diverse range of insights makes us better investors.

More on Investing Articles

Investing Articles

With an 8% dividend yield, I think this cheap FTSE 250 stock could be one not to miss

FTSE 250 stocks include a lot of potential passive income candidates right now, with even more 8%+ yields than the…

Read more »

Investing Articles

No savings at 30? Here’s how I’d start investing in a Stocks and Shares ISA

Charlie Carman explains why it's never too late to start investing in a Stocks and Shares ISA, even if it…

Read more »

Investing Articles

The NatWest share price is on fire! Should I buy?

The NatWest share price has climbed by 33% in the past five years, after a cracking start to 2024. Here's…

Read more »

Investing Articles

With the FTSE 100 soaring, here are 2 quality shares I’d buy today

This Fool's focusing on FTSE 100 shares as he looks to add to his holdings. Here are two in particular…

Read more »

Smart young brown businesswoman working from home on a laptop
Investing Articles

Is the Lloyds share price the biggest bargain for investors right now?

The Lloyds share price is rising but this Fool still thinks it's a bargain. Here's why he thinks investors should…

Read more »

Silhouette of a bull standing on top of a landscape with the sun setting behind it
Investing Articles

Why the Experian share price is soaring after Q4 results

The Experian share price is at all-time highs after the company’s latest trading update. But does 6% revenue growth justify…

Read more »

Young Black woman using a debit card at an ATM to withdraw money
Investing Articles

Best FTSE 100 bank shares right now: Lloyds or HSBC?

This Fool is wondering which of these FTSE 100 bank stocks look like a better buy for his ISA today.…

Read more »

Growth Shares

This out-of-favour UK growth stock could rise 89%, according to City analysts

This growth stock has been absolutely crushed over the last 12 months or so. But analysts at Deutsche Bank are…

Read more »