2 ‘unstoppable’ FTSE 100 shares I’d buy for a new ISA

The FTSE 100 includes some of the world’s best businesses. Our writer explores two high-quality picks that could bring long-term rewards.

| More on:

The content of this article was relevant at the time of publishing. Circumstances change continuously and caution should therefore be exercised when relying upon any content contained within this article.

You’re reading a free article with opinions that may differ from The Motley Fool’s Premium Investing Services. Become a Motley Fool member today to get instant access to our top analyst recommendations, in-depth research, investing resources, and more. Learn More.

Finger clicking a button marked 'Buy' on a keyboard

Image source: Getty Images

ISA season has arrived. 6 April was the first day I could add fresh funds to my Stocks and Shares ISA.

But with new money sitting there, I’m looking at which shares to buy next. More specifically, I’m considering FTSE 100 shares.

FTSE 100’s best retailer

The first Footsie share on my hit list is UK fashion/lifestyle retailer Next (LSE:NXT). I used to own this share many years ago when it was trading at around £10. Since then, it has multiplied by a whopping nine times.

A £5,000 investment would now be worth £43,500. It’s a shame I didn’t hold onto it. But that’s in the past. Next has been and continues to be an impressive operator.

Its business strategy over the years has kept it ahead of the competition, in my opinion. For instance, it was one of the first among peers to make a push towards online sales.

Today, it continues to innovate. For instance, it now operates a Total Platform product which allows third-party brands to use Next’s infrastructure services such as IT, warehousing and marketing.

This could be a key driver of future growth, especially in a changing retail environment.

A high-quality business

Next shares offer many of the characteristics that make a quality stock. For instance, it offers a double-digit return on capital employed. It’s also a profitable business that churns out free cash flow.

This enables it to reduce debt and return excess cash to shareholders.

Bear in mind that retail consumers still face elevated cost of living pressures. Weather can also play a part in a customer’s shopping habits. And both factors can impact near-term earnings.

That said, these are short-term factors. For the long-term, I’m confident that Next will continue to be one of the leading retailers in the UK.

That’s why this time when I buy the shares, I hope I hold on to them.

The big pharma giant

Another quality FTSE 100 share I’d buy is pharmaceutical giant Astrazeneca (LSE:AZN). It’s the Footsie’s second largest company, one spot behind Shell.

Astrazeneca is a world-class player in this industry. Over the past decade it has focused on research and development. And it now offers a rich pipeline of innovative medicine across oncology, biopharmaceuticals and rare diseases.

If executed well, this should provide an excellent source of earnings growth for many years.

Oncology represents 35% of its portfolio and sales rose 23% last year. I’d note that chief executive Pascal Soriot expects “another year of strong growth in 2024, driven by continued adoption of medicines across geographies”.

Spending spree

Astrazeneca has purchased several billion-dollar companies recently. And although this could strengthen its pipeline, it doesn’t come cheap. Large acquisitions tend to come with some risk too. That said, this mega-cap has ample experience to lean on.

It trades on a forward price to earnings ratio of 16. This is broadly in line with peers, but I’d say it’s not expensive given its strong pipeline and potential.

Overall, both FTSE 100 top picks could prove to be unstoppable players in a long-term ISA. That’s why I intend to buy them both soon.

Harshil Patel has no position in any of the shares mentioned. The Motley Fool UK has recommended AstraZeneca Plc. Views expressed on the companies mentioned in this article are those of the writer and therefore may differ from the official recommendations we make in our subscription services such as Share Advisor, Hidden Winners and Pro. Here at The Motley Fool we believe that considering a diverse range of insights makes us better investors.

More on Investing Articles

Chalkboard representation of risk versus reward on a pair of scales
Growth Shares

Why high oil prices could be good news for Lloyds shares

Jon Smith talks through the implications of elevated oil prices and translates that through to the potential impact on Lloyds'…

Read more »

Investing Articles

Lists of income stocks to buy almost never include this one — but with a forecast 8.2% yield, I think they should!

This FTSE firm, not always seen as an income play, has a forecast yield of 8.2%, underlining why it's one…

Read more »

Person holding magnifying glass over important document, reading the small print
Investing Articles

Aviva’s share price is down 13% to under £7, despite outstanding 2025 results! Time for me to buy more?

I think Aviva’s share price reflects an outdated view of the business, and that gap between perception and reality is…

Read more »

Arrow symbol glowing amid black arrow symbols on black background.
Investing Articles

Shell’s £33+ share price is near an all-time high, so why am I going to buy more as soon as possible?

Shell's strong cash generation and improving growth drivers contrast with a share price well below my valuation, suggesting major long‑term…

Read more »

DIVIDEND YIELD text written on a notebook with chart
Investing Articles

An 8.4% forecast yield but down 16%! Time for me to buy more of this FTSE 100 passive income star?

This FTSE 100 passive‑income machine is delivering rising payouts and strong forecasts, and its share price suggests the market hasn’t…

Read more »

CEO Mark Zuckerberg at F8 2019 event
Investing Articles

£10,000 invested in Meta Platforms Stock 5 years ago is now worth…

Meta Platforms has been throwing good money after bad at Reality Labs since 2021, but the stock has more than…

Read more »

Middle-aged white man pulling an aggrieved face while looking at a screen
Investing Articles

£7,500 invested in Diageo shares 5 weeks ago is now worth…

Our writer wonders if Diageo shares are worth a look at a 14-year low, or whether this FTSE 100 spirits…

Read more »

National Grid engineers at a substation
Investing Articles

Is Warren Buffett’s firm about to buy this FTSE 100 company?

There’s always speculation about what Warren Buffett’s company might be doing. But one UK idea has a bit more to…

Read more »