Is it too late to buy Open Orphan shares?

Open Orphan’s shares are up over 100% in the past six months. Is there no stopping this specialist pharmaceutical firm?

The content of this article was relevant at the time of publishing. Circumstances change continuously and caution should therefore be exercised when relying upon any content contained within this article.

When investing, your capital is at risk. The value of your investments can go down as well as up and you may get back less than you put in.

Read More

The content of this article is provided for information purposes only and is not intended to be, nor does it constitute, any form of personal advice. Investments in a currency other than sterling are exposed to currency exchange risk. Currency exchange rates are constantly changing, which may affect the value of the investment in sterling terms. You could lose money in sterling even if the stock price rises in the currency of origin. Stocks listed on overseas exchanges may be subject to additional dealing and exchange rate charges, and may have other tax implications, and may not provide the same, or any, regulatory protection as in the UK.

You’re reading a free article with opinions that may differ from The Motley Fool’s Premium Investing Services. Become a Motley Fool member today to get instant access to our top analyst recommendations, in-depth research, investing resources, and more. Learn More.

Six months ago, Open Orphan’s (LSE: ORPH) shares hit a low of 13.5p. Fast-forward to February 19th, 2021, the shares hit a high of 32.90p. Could the rapid share price acceleration be attributable to Open Orphan’s knack of winning new contracts?

On March 9th, Open Orphan further grabbed my attention (and I thought of the company as a possible contender for my SIPP) when its subsidiary Venn Life Science secured a contract with Oxford BioTherapeutics in order to advance a breast cancer trial study.  

Open Orphan seemed to be a on a roll in winning new business and, for diversification purposes, adding some pharma to my portfolio would be beneficial in the long term.

The firm said the contract was for a phase 1, open-label dose finding study, which would assess the safety, tolerability, pharmacokinetics and preliminary efficacy of ‘OBT076’, a CD205-directed antibody-drug conjugate, in recurrent and metastatic CD205-positive solid tumours and in women with CD205-positive HER2-negative metastatic breast cancer.

The breast cancer trial, if successful, could play a role in beating the fourth most common cause of cancer death in the UK, according to charity Cancer Research.

Open Orphan’s executive chairman Cathal Friel said: “This deal further demonstrates Open Orphan’s ability to execute on its significant pipeline of contracts with important pharmaceutical businesses.”

Expanding market

Over the past six months, the market for vaccine development and testing has grown rapidly, largely due to the outbreak of Covid-19. There is no doubt that this factor has benefited Open Orphan’s shares, and perhaps one of the reasons why the AIM-traded firm’s market capitalisation is growing – currently standing at £192m.

Open Orphan believes that governments and international pharmaceutical companies are making ‘catch-up’ investments in all types of vaccine development to ensure the effects of any global pandemic can be mitigated in the future. This will have a knock-on effect for Open Orphan’s hVIVO facility, the firm’s other commercial specialist service business.

Winning new contracts, an expanding vaccine development market and world class facilities – Open Orphan has Europe’s only 24-bedroom quarantine clinic with onsite virology – all make Open Orphan’s shares an attractive buy for me.

But what are the negatives? There are a few.

The pandemic has created a new type of “gold rush” in Covid-19 pharmaceutical and biotech shares, which might inevitably come to an end. Open Orphan shares could be the victim of hype and over-valuation, and there is a possible danger of buying this share at the top.

Back in October 2020, Open Orphan’s own brokers downplayed the prospects for the company’s share price despite securing a £10m Covid-19 challenge contract with the government. Arden Partners issued a buy rating on the stock with a target price of 32p, and joint broker finnCap also appeared to be backing a conservative outlook indicating a target price of 28p, with the shares trading around 29p today.

Should you invest, the value of your investment may rise or fall and your capital is at risk. Before investing, your individual circumstances should be assessed. Consider taking independent financial advice.

Sabuhi Gard has no position in any of the shares mentioned. The Motley Fool UK has no position in any of the shares mentioned. Views expressed on the companies mentioned in this article are those of the writer and therefore may differ from the official recommendations we make in our subscription services such as Share Advisor, Hidden Winners and Pro. Here at The Motley Fool we believe that considering a diverse range of insights makes us better investors.

More on Investing Articles

Middle-aged Caucasian woman deep in thought while looking out of the window
Investing Articles

Should I buy these UK shares for my portfolio?

This Fool has been searching for ways to capitalise on the commodity moves via UK shares. Here’s what he’s watching.

Read more »

Illustration of flames over a black background
Investing Articles

Just released: April’s higher-risk, high-reward stock recommendation [PREMIUM PICKS]

Fire ideas will tend to be more adventurous and are designed for investors who can stomach a bit more volatility.

Read more »

A senior group of friends enjoying rowing on the River Derwent
Investing Articles

£9,000 in savings? Here’s a FTSE 100 stock I’d buy to target a £30,652 annual second income!

Our writer highlights one top FTSE 100 share that he thinks could help create a portfolio large enough for a…

Read more »

Light bulb with growing tree.
Investing Articles

62% down! Is the Ceres Power share price now a green energy bargain?

Annual results from the green energy firm showed a company on the cusp of doubling sales. So why has the…

Read more »

Investing Articles

3 mid-cap UK defence shares to consider buying in 2024

Defence budgets are soaring as global conflicts increase the threat landscape, so I'm examining the value proposition of three defence-related…

Read more »

Investor looking at stock graph on a tablet with their finger hovering over the Buy button
Investing Articles

Hargreaves Lansdown investors have been buying dividend stocks BP and Shell. Should I?

Cherished dividend stocks BP and Shell have outperformed the FTSE 100 index so far in 2024. Paul Summers takes a…

Read more »

Young Asian man shopping in a supermarket
Dividend Shares

A 5% yield? Here’s the 3-year dividend forecast for Tesco shares

Jon Smith flags up the positive momentum for Tesco shares following the release of the full-year results and looks at…

Read more »

Investing Articles

Yields up to 12.3% 3 top shares investors should consider for a second income

Searching for ways to make a market-beating second income? These popular dividend stocks are worth serious consideration, says Royston Wild.

Read more »