We have some exciting news to share! The Motley Fool UK has now become an independent, UK-owned company, led by our long-serving UK management team — Mark Rogers, Chris Nials and Heather Adlington. In practical terms, it’s the same team you know, now fully focused on serving our UK readers and members.

Just as importantly, our approach remains unchanged: long-term, jargon-free, and on your side. We’ll be introducing a new name and brand over the coming weeks — we're very excited to share it with you and embark on this new chapter together!

3-Point Checklist: Should You Buy GlaxoSmithKline plc Or AstraZeneca plc?

In a battle between the UK’s two pharma giants, which firm has the edge, GlaxoSmithKline plc (LON:GSK) or AstraZeneca plc (LON:AZN)?

| More on:

The content of this article was relevant at the time of publishing. Circumstances change continuously and caution should therefore be exercised when relying upon any content contained within this article.

You’re reading a free article with opinions that may differ from The Motley Fool’s Premium Investing Services. Become a Motley Fool member today to get instant access to our top analyst recommendations, in-depth research, investing resources, and more. Learn More.

GlaxoSmithKline (LSE: GSK) (NYSE: GSK.US) recently completed a complex multi-billion dollar asset swap deal with Swiss firm Novartis, which I believe will help to kick-start Glaxo’s earnings growth and maintain the firm’s enviable cash generation and profit margins.

However, UK peer AstraZeneca (LSE: AZN) (NYSE: AZN.US) isn’t without its fans — in fact, the market is so confident in AstraZeneca’s prospects that the share price has retained most of the bid premium it accumulated last year, leaving the shares 16% higher than they were one year ago.

That’s a much better performance than GlaxoSmithKline (down 3%) or the FTSE 100 (up 4%) — so which company should you invest in today?

1. Profitability

Both companies are going through a period of change at the moment, and this is reflected in profit margins, which tumbled last year due to a mixed bag of exceptional costs.

In the table below, I’ve highlighted each company’s reported operating margins and their five-year average operating margins:

 

GlaxoSmithKline

AstraZeneca

Five-year average operating margin

22.9%

24.9%

2014 reported operating margin

15.6%

8.2%

Historically, both companies enjoyed very high operating margins — and those good times may well return.

Certainly both companies hope so: the adjusted ‘core’ profit figures published by each firm for 2014 give GlaxoSmithKline a core operating margin of 28.7% and AstraZeneca a similar figure of 26.6%.

However, many of the one-off costs reported last year have happened before — and may happen again. I reckon rebuilding both firms’ profit margins could take a few more years.

2. Income

The main attraction of both firms is income: historically, AstraZeneca and GlaxoSmithKline have offered high yields and strong dividend growth.

Today’s the yields remain attractive, but growth has slowed — so which firm looks more attractive?

 

GlaxoSmithKline

AstraZeneca

2015 prospective yield

5.1%

4.1%

Five-year dividend growth rate

+4.2%

1.9%

GlaxoSmithKline shareholders will also receive an 82p per share payout this year, as part of the recently-completed Novartis deal. This will add another 5.1% to Glaxo’s yield for 2015.

There are question marks over whether either firm will be able to increase its payout in 2015, but the benefit of the doubt has to go to GlaxoSmithKline, in my opinion.

3. Is the price right?

Neither AstraZeneca nor GlaxoSmithKline is obviously cheap, but I think that generous yields, decent profit margins and strong cash generation — plus expectations of future growth — mean that both look reasonably attractive at current prices.

 

GlaxoSmithKline

AstraZeneca

2015 forecast P/E

17.2

16.2

2016 forecast P/E

16.5

16.5

There’s not much in it: my view remains that Glaxo’s deal with Novartis will help the firm escape the impact of recent patent expiries and give Glaxo a head start over AstraZeneca in returning to growth.

Roland Head owns shares in GlaxoSmithKline. The Motley Fool UK has recommended GlaxoSmithKline. We Fools don't all hold the same opinions, but we all believe that considering a diverse range of insights makes us better investors.

More on Investing Articles

Investor looking at stock graph on a tablet with their finger hovering over the Buy button
Investing Articles

Am I crazy to consider this risky FTSE 100 bank stock over Rolls-Royce shares?

Mark Hartley weighs up the pros and cons of investing in a FTSE 100 growth stock that’s giving Rolls-Royce shares…

Read more »

Road 2025 to 2032 new year direction concept
Investing Articles

How did HSBC pay more passive income via dividends in 2025 than any other British company?

Despite only an average yield, HSBC was the UK's passive income hero of 2025, paying out more in dividends than…

Read more »

The flag of the United States of America flying in front of the Capitol building
Investing Articles

1 S&P 500 name I can’t stop buying in my Stocks and Shares ISA

S&P 500 software companies have been falling out of the sky. But Stephen Wright's been focusing on one in particular…

Read more »

Young brown woman delighted with what she sees on her screen
Investing Articles

Analysts reckon the Lloyds share price should be 21% higher!

James Beard’s been looking at the latest Lloyds Banking Group share price forecasts. But is the bank’s stock really worth…

Read more »

Investing Articles

How much time and money would it take to become a stock market millionaire?

Is it realistic to aim for a million by investing a few hundred pounds a week in the stock market?…

Read more »

Fans of Warren Buffett taking his photo
Investing Articles

Want to start buying shares? How good are you at these 3 things?

This trio of simple questions can help provide some food for thought to anyone who wonders whether they are ready…

Read more »

Three generation family are playing football together in a field. There are two boys, their father and their grandfather.
Investing Articles

How to target a £1,183 monthly passive income in a SIPP for life!

Own a Self-Invested Personal Pension (SIPP)? Here's how you could maximise your chances of a comfortable retirement by buying dividend…

Read more »

Affectionate Asian senior mother and daughter using smartphone together at home, smiling joyfully
Investing Articles

What are the best shares to buy to earn £1m or more in an ISA?

Searching for the best ISA stocks to buy to target a million? Royston Wild discusses the key things to look…

Read more »