Why Shire PLC Has Beaten AstraZeneca plc And GlaxoSmithKline plc In 2014

Never mind AstraZeneca plc (LON: AZN) and GlaxoSmithKline plc (LON: GSK), Shire PLC (LON:SHP) is this year’s big pharmaceuticals winner!

| More on:

The content of this article was relevant at the time of publishing. Circumstances change continuously and caution should therefore be exercised when relying upon any content contained within this article.

You’re reading a free article with opinions that may differ from The Motley Fool’s Premium Investing Services. Become a Motley Fool member today to get instant access to our top analyst recommendations, in-depth research, investing resources, and more. Learn More.

If you invest in pharmaceuticals, Shire (LSE: SHP) is the one you should have bought this year.

It’s up 60% in the past 12 months to 4,395p, easily beating the FTSE 100‘s big two — AstraZeneca (LSE: AZN) (NYSE: AZN.US) is up a still-nice 32% to 4,618p, but GlaxoSmithKline (LSE: GSK) (NYSE: GSK.US) shares have lost 11% to 1,378p.

Rising profits

Looking at Shire’s past results, it’s not surprising the shares have done well. For the year ended December 2013, Shire reported a 77% rise in earnings per share (EPS) from continuing operations, and an underlying non-GAAP rise of 23%. That came from a 9% rise in revenue to $4.9bn, with sales of a number of key treatments for ADHD, ulcerative colitis and a wide variety of other ailments growing nicely.

The firm also has an impressive number of candidates in late stages of its development pipeline, and that’s helped inspire analysts to forecast a further 35% rise in EPS for 2014. So far this year things are looking good, with total revenues at Q3 time up 32% over the same period last year.

It’s not really surprising, then, that there’s a pretty heavy Buy consensus amongst analysts at the moment.

A revolution

Over at AstraZeneca, that 32% rise is a result that few of us would have expected so soon when new CEO Pascal Soriot took over in October 2012. At the time, the company was struggling with the loss of patent protection on a number of key drugs and the resulting competition from generic alternatives, and its development pipeline was looking unimpressive.

AstraZeneca is not back to rising EPS yet, and there’s a fall of 18% expected this year. But the about-turn that Mr Soriot has effected in such a short time has been dramatic. Non-key assets have been offloaded, AstraZeneca’s pipeline is looking dramatically better now, and we might even see EPS growth next year — about two years ahead of earlier expectations.

The recovery has put the shares on a forward P/E of 18 based on the current 2015 consensus, but coupled with a decently-covered 3.7% dividend yield and the potential value of the firm’s late-stage pipeline candidates, that could prove to be good value.

Things are looking a bit tougher at GlaxoSmithKline, and the failure to sell off a portfolio of its older drugs earlier this month didn’t impress investors — the price has dipped since it was announced.

Cheaper valuation

At the nine-month stage, revenues were down 14%. But that was in line with expectations, and there’s an end to falling EPS already forecast for 2015 (while for AstraZeneca it’s still just a hope). Dividends should yield around 5.5%, although they won’t be as well covered, and the shares are on a fairly modest P/E of just over 15.

On the whole, all three of these look like good prospects — but 2015 could easily end up belonging to Shire again.

Alan Oscroft has no position in any shares mentioned. The Motley Fool UK has recommended GlaxoSmithKline. We Fools don't all hold the same opinions, but we all believe that considering a diverse range of insights makes us better investors.

More on Investing Articles

Woman riding her old fashioned bicycle along the Beach Esplanade at Aberdeen, Scotland.
Investing Articles

How to target a million-pound SIPP by investing in UK shares

Harvey Jones shows how investors could target a SIPP worth a life-changing seven-figure sum, by investing in FTSE 100 dividend…

Read more »

A rear view of a female in a bright yellow coat walking along the historic street known as The Shambles in York, UK which is a popular tourist destination in this Yorkshire city.
Investing Articles

Buying £20k of BAE Systems shares could give me a £360 income this year!

Looking for the best dividend stocks out there? Royston Wild explains why BAE Systems shares are worth considering.

Read more »

UK financial background: share prices and stock graph overlaid on an image of the Union Jack
Investing Articles

Trying to make a million from FTSE 100 shares? Here’s where to start today

FTSE 100 investor Andrew Mackie highlights how the best UK shares are often those that use weak markets to quietly…

Read more »

Portrait Of Senior Couple Climbing Hill On Hike Through Countryside In Lake District UK Together
Investing Articles

How the UK State Pension measures up against other countries — and why it’s not enough

Mark Hartley weighs the UK State Pension against other nations, revealing why it’s important for Britons to explore additional options.

Read more »

Three signposts pointing in different directions, with 'Buy' 'Sell' and 'Hold' on
Investing Articles

A stock market crash this summer? Here’s how it could help

With emotion running high, the stock market is in a funny mood right now. And it can make investing choices…

Read more »

Close-up of children holding a planet at the beach
Investing Articles

Investors are pouring cash into Scottish Mortgage Investment Trust. Is it all about SpaceX?

Is this the perfect time to join the revived space race, by grabbing a chunk of the UK's most popular…

Read more »

The words "what's your plan for retirement" written on chalkboard on pavement somewhere in London
Investing Articles

Here’s 1 way to pick buy-and-forget stocks for a lifetime SIPP

Volatile stock markets have shaken the confidence of SIPP and ISA investors in 2026. We need a low-stress way to…

Read more »

Female student sitting at the steps and using laptop
Investing Articles

1 quality stock to consider buying for a brand spanking new ISA

Ben McPoland highlights an excellent growth stock that he's looking to buy in the coming weeks. The company is growing…

Read more »