How Did AstraZeneca plc End Up Thrashing Rival GlaxoSmithKline plc?

AstraZeneca plc (LON: AZN) has handed out a real thrashing to pharmaceutical rival GlaxoSmithKline plc (LON: GSK) lately, but Harvey Jones suggests the tables could soon turn.

| More on:

The content of this article was relevant at the time of publishing. Circumstances change continuously and caution should therefore be exercised when relying upon any content contained within this article.

You’re reading a free article with opinions that may differ from The Motley Fool’s Premium Investing Services. Become a Motley Fool member today to get instant access to our top analyst recommendations, in-depth research, investing resources, and more. Learn More.

A couple of years ago, AstraZeneca (LSE: AZN) (NYSE: AZN.US) was the whipping boy of the pharmaceutical world. Its drugs pipeline was drying up, patents were expiring and sales were plunging. The share price had gone nowhere for ages. Brokers were giving it a beating, with a spate of downgrades. Even currency movements were against it. Astra was under the cosh.

GlaxoSmithKline (LSE: GSK) (NYSE: GSK.US), by contrast, was the much-admired head boy of FTSE pharmo. It had won applause for its strategy of cutting costs and offloading non-core holdings. Its drugs pipeline looked healthy and chief executive Sir Andrew Witty’s strategy of shifting from “white pills and western markets” towards consumer healthcare and emerging markets had been awarded top marks.

Tables Turned

Then look what happened. Glaxo’s share price grew a disappointing 12% over the past two years, trailing the FTSE 100’s return of nearly 18%. AstraZeneca, however, returned a startling 44%. No longer the whipping boy, AZN now holds the whip hand. So what went right (or wrong)?

AZNGolden boy Glaxo’s reputation has been tarnished by bribery scandals, in China, Iraq and Poland, with more apparently set to follow Jordan and Lebanon. For those who think these allegations don’t matter, pharmaceuticals and vaccines sales in China have since fallen 29%. 

Glaxo has also faced a string of patented expiries and late-stage failures, notably megablockbuster heart drug Darapaldib and cancer vaccine MAGE-A3. Maybe the signs were on the wall in February, when Warren Buffett sold off his remaining $17 million stake.

Big Pharmo, Big Deals

AstraZeneca has been shining by comparison. Its drugs pipeline is growing, with 104 ongoing projects, of which 90 are in the clinical phase of development. Revenues rose 3% to $6.4 billion in the first quarter. Its five designated growth areas (emerging markets, Japan, Brilinta and its diabetes and respiratory franchises) delivered an extra $1.2 billion of revenue in 2013.

All of which is very nice, but it’s takeover talk that has really got investor juices flowing. Astra’s shares soared 7% in a day on rumours that it is a target for US giant Pfizer. 

This added to the excitement gripping the sector, following the multi-billion dollar three-way link-up between Glaxo, Swiss drugmaker Novartis and US medicines group Eli Lilly, who plan to build a world-leading consumer healthcare business. Investors love a deal, and Glaxo also leapt 6% in a day. Big pharmo deal making is back, with a vengeance, it seems. 

AstraZeneca may have turned the tables on Glaxo, but it may struggle to hold its advantage for investors, especially if recent takeover speculation comes to nought. Glaxo’s three-part deal could really drive future shareholder value, especially if it allows the company to dispose of some of its established businesses. Astra may have thrashed its rival lately, but I reckon Glaxo is cracking the whip today.

Harvey doesn't own shares in any company mentioned in this article. The Motley Fool has recommended shares in GlaxoSmithKline.

More on Investing Articles

Night Takeoff Of The American Space Shuttle
Growth Shares

How UK investors can get access to the $2trn SpaceX stock IPO TODAY

Investors in the UK can get exposure to space powerhouse SpaceX today via several investment trusts that trade on the…

Read more »

Young black colleagues high-fiving each other at work
Investing Articles

Down 23% from its highs, I’ve just bagged myself a FTSE 100 bargain!

Stephen Wright has seized the opportunity to buy shares in a FTSE 100 company with outstanding growth prospects at an…

Read more »

Close-up image depicting a woman in her 70s taking British bank notes from her colourful leather wallet.
Investing Articles

How to turn an empty ISA into £100 a month in passive income

Stephen Wright outlines how real estate investment trusts can help UK investors aim for £100 a month in passive income…

Read more »

Man riding the bus alone
Investing Articles

Down 23%! Should I buy Meta Platforms for my ISA or SIPP?

Meta stock looks undervalued after sliding steadily lower since last summer. But should I buy the social media giant for…

Read more »

A rear view of a female in a bright yellow coat walking along the historic street known as The Shambles in York, UK which is a popular tourist destination in this Yorkshire city.
Investing Articles

£5,000 invested in Greggs shares 2 years ago is now worth…

Anyone who bought Greggs' shares two years ago will now be sitting on heavy losses. Is there potential for a…

Read more »

Investing Articles

10 days to the next stock market crash?

What happens to the stock market when the current ceasefire in the Middle East expires? And what should investors do…

Read more »

Middle-aged Caucasian woman deep in thought while looking out of the window
Investing Articles

How to try and double the State Pension with just £30 a week

By saving money each week and investing regularly, even someone without a lot of cash to spare can aim to…

Read more »

UK financial background: share prices and stock graph overlaid on an image of the Union Jack
Investing Articles

2 badly beaten-down small caps to consider for a £20,000 Stocks and Shares ISA

Ben McPoland highlights a pair of UK small caps that have sold off heavily, making them worth considering for a…

Read more »