Biden bounce and vaccine vision! The FTSE 100 surges over 5%! Which shares should I buy?

As global stock markets enjoyed a surging start to the week, I look at what I think are the best FTSE 100 stock buys for the years ahead.

The content of this article was relevant at the time of publishing. Circumstances change continuously and caution should therefore be exercised when relying upon any content contained within this article.

You’re reading a free article with opinions that may differ from The Motley Fool’s Premium Investing Services. Become a Motley Fool member today to get instant access to our top analyst recommendations, in-depth research, investing resources, and more. Learn More.

In a double-barrel bounce, the FTSE 100 and other financial markets skyrocketed yesterday. First thing, the markets rallied in response to a Biden presidency confirmed over the weekend. This was later followed by an announcement that Pfizer’s Covid-19 vaccine shows 90% effectiveness in a large-scale trial. While it will still be some time before the vaccine is in widespread use, it puts a long overdue but positive slant on the future. Hopes are high that a vaccine rollout will begin before the year end.

No quick fix

While this news is exciting and makes a nice change, I expect market volatility will continue for some time. The Pfizer and BioNTech trial data involved around 40K participants with only 94 showing symptoms. It’s not yet been peer-reviewed, which makes the integrity of the results questionable in the interim. Nevertheless, an independent board, hired by Pfizer, did look over the results.

Biden has named Michael Osterholm to his Covid-19 Advisory Board. Mr Osterholm is a well-known figure in the epidemiology arena and has warned the US is “about to enter Covid hell” over the next three to four months. This is a reminder that until a vaccine is widely distributed, the virus is very much here and spreading like wildfire. Europe and the UK are also seeing positive cases and deaths rising. This does not bode well for a continuous rise in the FTSE 100 and other stock markets.

What shares to buy now?

Even if it’s short-lived, what the Biden bounce has done is give us a glimpse into the stocks that will thrive when normality resumes. I was surprised to see B&M and Reckitt Benckiser fall. On the flip side, oil stocks were flying, and Saga soared over 25%. Aston Martin rose over 12% and Smith & Nephew over 17% but Rolls-Royce took the prize for the FTSE 100’s biggest riser at nearly 75% up at one point.

As I don’t think we’re on the home straight just yet, I think it’s a bit premature to be buying travel stocks such as Saga. I’d be more tempted by Aston Martin as a contrarian buy, but it’s still very risky. Profitability is at least two years away, but if it can make it through the bad times, then its growth trajectory could be massive.

A FTSE 100 stock I like

I like Smith & Nephew because it makes sense to me as a long-term growth stock. The company makes replacement knees and hips and specialises in surgical robotics. While the pandemic is causing a backlog in operations to build up, this is a temporary pause. Once regular operating conditions resume, demand should rise. Also, the rollout of 5G around the world (and eventually 6G) is projected to revolutionise robotic surgery. I think this is a good long-term buy because it has the potential to grow for many years to come.

Widespread vaccine use is the magic bullet the world is waiting for, but it’s going to take time to get there. In the meantime, I expect the markets to continue their 2020 trend of volatility. I’ll be taking a cautious approach to investing with the distant future in mind.

Kirsteen has no position in any of the shares mentioned. The Motley Fool UK has recommended B&M European Value. Views expressed on the companies mentioned in this article are those of the writer and therefore may differ from the official recommendations we make in our subscription services such as Share Advisor, Hidden Winners and Pro. Here at The Motley Fool we believe that considering a diverse range of insights makes us better investors.

More on Investing Articles

GSK scientist holding lab syringe
Investing Articles

Why is everyone buying GSK shares?

GSK shares have been outperforming the FTSE 100 in 2026. Paul Summers takes a closer look and asks whether this…

Read more »

Middle-aged white man pulling an aggrieved face while looking at a screen
Investing Articles

£10,000 invested in easyJet shares at the start of 2026 is now worth…

Anyone buying easyJet shares will have endured a rough ride since January. Paul Summers wonders whether things could get even…

Read more »

Close-up of a woman holding modern polymer ten, twenty and fifty pound notes.
Investing Articles

5 years ago, £5,000 bought 2,645 Barclays shares. But how many would it buy now?

Despite delivering an impressive return since April 2021, Barclays' shares have lagged the FTSE 100's other banks. James Beard considers…

Read more »

Side of boat fuelled by gas to liquids, advertising Shell GTL Fuel
Investing Articles

5 years ago, £5,000 bought 354 Shell shares. But how many would it buy now?

When it comes to Shell’s numbers, most of them are impressive. And it’s no different when looking at the recent…

Read more »

A rear view of a female in a bright yellow coat walking along the historic street known as The Shambles in York, UK which is a popular tourist destination in this Yorkshire city.
Investing Articles

I asked ChatGPT if I should buy Aviva, Diageo or BAE Systems stock and it said…

Aviva, Diageo and BAE Systems shares are popular FTSE 100 picks. But which of the three does ChatGPT like the…

Read more »

Tesla car at super charger station
Investing Articles

SpaceX’s IPO threatens to leave the Tesla share price on the forecourt

As Elon Musk starts fuelling the engines for a SpaceX IPO, could the Tesla share price get left in the…

Read more »

Investor looking at stock graph on a tablet with their finger hovering over the Buy button
US Stock

A once-in-a-decade chance to buy software stocks?

Michael Burry thinks now is the time to think about buying falling tech stocks. But it might depend on which…

Read more »

Young mixed-race couple sat on the beach looking out over the sea
Investing Articles

Here’s how a £20k ISA could generate a £1,000 weekly second income

Drip-feeding money into a Stocks and Shares ISA can put you on track to a four-figure second income. Royston Wild…

Read more »