Is GlaxoSmithKline a screaming buy after this news?

Following the results of a landmark drug trial, GlaxoSmithKline plc (LON: GSK) could be a screaming buy, says Rupert Hargreaves.

The content of this article was relevant at the time of publishing. Circumstances change continuously and caution should therefore be exercised when relying upon any content contained within this article.

You’re reading a free article with opinions that may differ from The Motley Fool’s Premium Investing Services. Become a Motley Fool member today to get instant access to our top analyst recommendations, in-depth research, investing resources, and more. Learn More.

At the end of October, ViiV Healthcare, the joint venture between GlaxoSmithKline (LSE: GSK) and Pfizer, announced the results of a trail for a landmark treatment designed to help improve the lives of people living with HIV.

The phase III First Long-Acting Injectable Regimen trail, or FLAIR for short, was designed to establish if adults infected with type-1 HIV would see a similar improvement in health by taking a once-a-month injectable drug regime, rather than a daily oral medication (Triumeq). The study found that the injections had a similar effect to Triumeq over a 48-week period, in effect, reducing the number of days a person receives treatment from 365, to just 12.

HIV breakthrough

The positive results from the FLAIR trial are, without doubt, a massive deal for Glaxo and ViiV. If approved for sale by regulators, the new once-a-month injection could help the company grab market share from rivals in the $20bn-a-year global HIV market. At present, ViiV has around a fifth of the market, but with its new treatment ready to go, this could climb rapidly in the years ahead.

ViiV’s growth could be a huge bottom line boost for Glaxo. The group owns around three-quarters of the business, with the rest split between Pfizer and Japanese pharmaceutical group Japanese Shionogi. Both partners have put options that allow them to sell their shares to Glaxo for around £2bn in total. Glaxo has said in the past that it would welcome such a deal. 

And even if no deal emerges, analysts have speculated that income from ViiV could account for around 50% of group operating profit by 2020 — this estimate doesn’t take into account any boost to sales from the new game-changing, once-a-month HIV treatment, and the market share gains it could achieve. With ViiV making $0.75 in profit for every $1 of sales, any improvement in sales will be a huge boon for Glaxo and its investors.

The cheapest on the market

There’s far more to Glaxo than ViiV. This is just one part of the overall group but is an extremely profitable one. It’s also growing much faster than other divisions. 

Still, other divisions, such as the group’s vaccines business, are also putting in a strong showing. Vaccines turnover jumped 17% year-on-year at constant exchange rates in the third quarter, thanks to rising sales of Glaxo’s shingles medication.

With the group firing on all cylinders, I believe that shares in Glaxo could now be a ‘screaming buy’ after the result of ViiV’s landmark trial. However, despite the ownership of this world-leading partnership, shares in Glaxo are the cheapest of the Big Pharma group. The stock is trading at just 13 times forward earnings, compared to Pfizer’s 14, Johnson & Johnson’s 16.6, and Merck’s 15.8. On top of the discount valuation, shares in Glaxo also yield 5.3%.

So overall, considering the company’s future growth potential, its valuation, discount the rest of the global pharmaceutical sector, and market-beating dividend yield, I’m a buyer of Glaxo today.

Rupert Hargreaves owns shares in GlaxoSmithKline. The Motley Fool UK owns shares of and has recommended GlaxoSmithKline. The Motley Fool UK owns shares of Johnson & Johnson and has the following options: short January 2019 $140 calls on Johnson & Johnson. Views expressed on the companies mentioned in this article are those of the writer and therefore may differ from the official recommendations we make in our subscription services such as Share Advisor, Hidden Winners and Pro. Here at The Motley Fool we believe that considering a diverse range of insights makes us better investors.

More on Investing Articles

Female student sitting at the steps and using laptop
Investing Articles

UK stocks: the contrarian choice for 2026

UK stocks aren’t the consensus choice for investors at the moment. But some smart money managers who are looking to…

Read more »

Investing Articles

Down 20% in 2025, shares in this under-the-radar UK defence tech firm could be set for a strong 2026

Cohort shares are down 20% this year, but NATO spending increases could offer UK investors a huge potential opportunity going…

Read more »

Young Caucasian woman with pink her studying from her laptop screen
Investing Articles

New to investing? Here’s Warren Buffett’s strategy for starting from scratch

Warren Buffett says he could find opportunities to earn a 50% annual return in the stock market if he was…

Read more »

Investing Articles

Can the sensational Barclays share price do it all over again in 2026?

Harvey Jones is blown away by what the Barclays share price has been doing lately. Now he looks at whether…

Read more »

Investing Articles

Prediction: in 2026 mega-cheap Diageo shares could turn £10,000 into…

Diageo shares have been burning wealth lately but Harvey Jones says long-suffering investors in the FTSE 100 stock may get…

Read more »

Investing Articles

This overlooked FTSE 100 share massively outperformed Tesla over 5 years!

Tesla has been a great long-term investment, but this lesser-known FTSE 100 company would have been an even better one.

Read more »

A pastel colored growing graph with rising rocket.
Investing Articles

I’m backing these 3 value stocks to the hilt – will they rocket in 2026?

Harvey Jones has bought these three FTSE 100 value stocks on three occasions lately, averaging down every time they fall.…

Read more »

Investing Articles

Can the barnstorming Tesco share price do it all over again in 2026?

Harvey Jones is blown away by just how well the Tesco share price has done lately, and asks whether the…

Read more »