GlaxoSmithKline plc vs Shire PLC: Which Pharma Stock Is The Better Buy?

If you could only choose to buy one, should you add GlaxoSmithKline plc (LON: GSK) or Shire PLC (LON: SHP) to your portfolio?

The content of this article was relevant at the time of publishing. Circumstances change continuously and caution should therefore be exercised when relying upon any content contained within this article.

You’re reading a free article with opinions that may differ from The Motley Fool’s Premium Investing Services. Become a Motley Fool member today to get instant access to our top analyst recommendations, in-depth research, investing resources, and more. Learn More.

2015 is forecast to be a challenging year for both GlaxoSmithKline (LSE: GSK) (NYSE: GSK.US) and Shire (LSE: SHP) (NASDAQ: SHPG.US). That’s because both pharmaceutical companies are forecast to post declines in their bottom lines in the current year, which is likely to impact negatively upon sentiment in the short term.

However, looking at next year, it is expected to be much brighter for both stocks. In fact, the impact of cost savings is expected to be felt at GlaxoSmithKline, with its earnings forecast to rise by 4% in 2016. Although this is less than the FTSE 100‘s prospective growth rate, it shows that the drug maker is finally moving in the right direction after a highly challenging period. Meanwhile, Shire is expected to increase its net profit by a much more impressive 17% next year, as the company’s sales increase and it continues to turn a great pipeline into higher profitability for investors.

Valuation

While Shire has better growth prospects than GlaxoSmithKline for next year, its share price is less attractive than that of GlaxoSmithKline. For example, Shire trades on a price to earnings (P/E) ratio of 21.8, which is considerably higher than the FTSE 100’s P/E ratio of 16. As such, Shire may have less scope for an upward rating expansion than GlaxoSmithKline, since the latter has a far more appealing P/E ratio of 17.5. And, with GlaxoSmithKline being the larger and better diversified of the two, it could be argued that it should command a higher P/E ratio relative to Shire.

Income Prospects

While GlaxoSmithKline yields a very appealing 5.1%, Shire’s yield is just 0.4% at the present time. And, even though Shire is expected to increase dividends per share by 12.8% next year, it will take a very long period before it becomes as appealing as GlaxoSmithKline when it comes to income prospects. As such, and while GlaxoSmithKline is expected to hold dividends flat in 2016, it remains a much more appealing income stock.

Looking Ahead

While pharma stocks are often viewed as being relatively defensive, GlaxoSmithKline has a beta of 1 and Shire has a beta of 1.3, which means that they are set to offer little in the way of reduced volatility moving forward. And, while both stocks have considerable future potential, the fact that GlaxoSmithKline has a lower rating and much better income prospects means that it remains the better buy of the two companies. Certainly, Shire has greater growth potential but, when it comes to which stock offers the most appealing risk/reward ratio, GlaxoSmithKline remains the more favourable option.

Peter Stephens owns shares of GlaxoSmithKline. The Motley Fool UK has recommended GlaxoSmithKline. We Fools don't all hold the same opinions, but we all believe that considering a diverse range of insights makes us better investors.

More on Investing Articles

British union jack flag and Parliament house at city of Westminster in the background
Investing Articles

Is Raspberry Pi the next Nvidia stock?

The Raspberry Pi (LSE:RPI) share price exploded 46% higher in the FTSE 250 today. Might this be the start of…

Read more »

Senior woman potting plant in garden at home
Investing Articles

Thinking of stuffing a SIPP with high-yield shares? 3 things to consider

A SIPP filled with shares offering juicy dividends can seem tempting. Christopher Ruane explains some potential pros and cons of…

Read more »

ISA coins
Investing Articles

Does this weekend’s ISA deadline make now a good time to start buying shares?

With a key ISA deadline looming this weekend, does it make a difference whether someone starts buying shares now or…

Read more »

National Grid engineers at a substation
Investing Articles

If inflation soars, can the National Grid dividend keep up?

With the risk of higher inflation getting stronger, our writer weighs up whether the National Grid dividend might earn the…

Read more »

Lady taking a bottle of Hellmann's Real Mayonnaise from a supermarket shelf
Investing Articles

Could getting out of the food business help the Unilever share price?

Unilever and McCormick today announced a transformational corporate deal. Our writer weighs some of its attractions and risks.

Read more »

UK financial background: share prices and stock graph overlaid on an image of the Union Jack
Investing Articles

Why did Raspberry Pi shares just jump 35%?

Raspberry Pi shares have been in the doldrums in the past 12 months. But is that all changing, after a…

Read more »

Businessman hand stacking money coins with virtual percentage icons
Investing Articles

How much second income could investors earn with 9% dividends from Legal & General shares?

Investors looking to build up a second income portfolio have a good few FTSE 100 shares with big dividends to…

Read more »

Rolls-Royce engineer working on an engine
Investing Articles

£5,000 invested in Rolls-Royce shares just 2 years ago is now worth…

Rolls-Royce shares have fallen some way back from a recent 52-week peak, as global events impact them and the firm…

Read more »