Worried about buying at the top of the market? Look closer at this FTSE 100 giant

The FTSE 100’s largest stock could be one of the best value plays hiding in plain sight. Dr James Fox explains his optimism about the company.

| More on:

The content of this article was relevant at the time of publishing. Circumstances change continuously and caution should therefore be exercised when relying upon any content contained within this article.

You’re reading a free article with opinions that may differ from The Motley Fool’s Premium Investing Services. Become a Motley Fool member today to get instant access to our top analyst recommendations, in-depth research, investing resources, and more. Learn More.

piggy bank, searching with binoculars

Image source: Getty Images

The FTSE 100 isn’t far off all-time highs. And while some investors may love that momentum, others will be a little worried about investing in a potentially stretched market.

The reality is that while some parts of the stock market are richly valued, especially US tech, it’s not universally the case.

In fact, I believe there are still great value plays to be had. One is AstraZeneca (LSE:AZN) — the largest company on the FTSE 100.

What makes the stock so great?

To start with, AstraZeneca’s forward price-to-earnings-to-growth (PEG) ratio of 1.2 is just 3% higher than its five-year average forward PEG.

What does that tell us?

Well, investors are currently quite used to paying more for a stock on a valuation basis than they did a couple of years ago.

This tells us that AstraZeneca is still pretty much the same price on a growth-adjusted metric.

But it’s not just on self-comparisons where AstraZeneca excels.

It’s a behemoth of the pharma and biotech world, and that means we should compare it against its global peers and not just those in the UK.

Sticking with the forward PEG ratio, we can see that the company is trading at a 35% discount to its global peers.

This is great sign of relative value. And it’s worth recognising that AstraZeneca supports this with a strong balance sheet and near-2% dividend yield.

While data can occasionally be misleading, the above figures tell me that this is a stock worth considering.

Business as usual

There have been several things weighing on the AstraZeneca share price over the past 12 months. A China scandal, a traditionally vaccine-wary US Secretary of Health and new tariff policy.

However, most of those concerns appear to be in the past. Earlier in October, AstraZeneca struck a landmark agreement with the US government to offer its drugs to Medicaid at “most-favoured-nation” (MFN) pricing. This means matching the lowest price it charges in other developed countries.

In turn, this means it’s really about business as usual for AstraZeneca. And that means focusing on a very large pipeline of treatments, drugs, and vaccines.

While it can take years to really dive into a company’s pipeline and assess how much value a drug or treatment may bring to patients and net sales, it’s also worth noting that many pipeline products never make it to market.

This, itself, is a risk that all investors must take when investing in pharma companies like AstraZeneca. It may spend billions on R&D but never see a penny for it.

However, the size of the portfolio does mitigate some of that risk. As does the company’s focus on advancing treatments in oncology and rare diseases — these are critical areas of medical development.

Personally, I think investors should be considering this FTSE 100 stock. It still looks cheap and it’s in an industry that isn’t going anywhere.

James Fox has positions in AstraZeneca Plc. The Motley Fool UK has recommended AstraZeneca Plc. Views expressed on the companies mentioned in this article are those of the writer and therefore may differ from the official recommendations we make in our subscription services such as Share Advisor, Hidden Winners and Pro. Here at The Motley Fool we believe that considering a diverse range of insights makes us better investors.

More on Investing Articles

Two white male workmen working on site at an oil rig
Dividend Shares

More oil wobbles as the BP share price dives 7% in a day!

The BP share price has been wildly volatile in 2026, bouncing around with each new move in the US-Iran war.…

Read more »

British bank notes and coins
Investing Articles

Meet the 9.6%-yielding income share that could keep growing its payout!

This income share yields close to 10% -- and has grown its dividend per share year after year for well…

Read more »

Fireworks display in the shape of willow at Newcastle, Co. Down , Northern Ireland at Halloween.
Investing Articles

When will Barclays shares hit £10?

Barclays shares were close to £1 not so long ago, but could they do the unthinkable and make it to…

Read more »

Picture of an easyJet plane taking off.
Investing Articles

easyJet shares have bounced back before. On a P/E ratio of 6, could they do it again?

Our writer thinks easyJet shares could turn out to be a terrific bargain from a long-term perspective. So is he…

Read more »

Stack of British pound coins falling on list of share prices
Investing Articles

Could National Grid shares offer me a dividend that won’t be hurt by inflation?

National Grid aims to inflation-proof its dividend per share with a policy of annual rises that match inflation. Is our…

Read more »

Young female business analyst looking at a graph chart while working from home
Investing Articles

Here’s what happened to £1,000 invested in the past 2 stock market crashes

History may not repeat itself, but our writer reckons there are lessons to be learned from what recent stock market…

Read more »

Young Caucasian woman at the street withdrawing money at the ATM
Investing Articles

Here’s how the HSBC share price reached an all-time high… and what might be next

HSBC’s record share price reflects a strong rebound in profits and investor confidence, but future gains may be bumpier from…

Read more »

UK coloured flags waving above large crowd on a stadium sport match.
Investing Articles

Investors tempted by beaten-down Diageo shares should mark 6 May on their calendars now

Diageo is a top British blue-chip but its shares have come under fire in recent years. Harvey Jones hopes investors…

Read more »