If I’d put £25,000 into the FTSE 350 at the start of 2024, here’s how much I’d have today!

Many FTSE shares have rebounded this year as interest rates look set to keep heading lower and market appetite for more risk picks up.

| More on:

The content of this article was relevant at the time of publishing. Circumstances change continuously and caution should therefore be exercised when relying upon any content contained within this article.

British coins and bank notes scattered on a surface

Image source: Getty Images

You’re reading a free article with opinions that may differ from The Motley Fool’s Premium Investing Services. Become a Motley Fool member today to get instant access to our top analyst recommendations, in-depth research, investing resources, and more. Learn More.

The blue-chip FTSE 100 and mid-cap FTSE 250 are both up year to date. Here, I’ll look at what I’d have now if I’d invested £25k in the FTSE 350 index at the beginning of January.

What is it?

The index in question combines the largest 350 companies listed on the London Stock Exchange, specifically the constituents of the FTSE 100 and FTSE 250.

It offers a broad view of UK corporate performance, spanning diverse sectors like finance, healthcare, energy, and consumer goods. As such, it can be seen as a benchmark for the overall economic health of the UK.

How much?

Unfortunately, the UK economy hasn’t exactly been firing on all cylinders in recent times. Perhaps this is why the FTSE 350 has returned just 30.7% in the past five years, including dividends.

Things have picked up a bit lately though. As of 30 September, the year-to-date total return was approximately 10%. This means that I’d have around £27,500 in my account if I’d invested £25,000 in a tracker like the iShares 350 UK Equity Index Fund.

With inflation falling and more interest rate cuts on the horizon, consumers should have more money to spend. Therefore, I wouldn’t be surprised to see the index inch higher in the coming months.

Buying individual shares

I often look at the S&P 500 — up 200% in 10 years with dividends — and wonder if I should just buy a US tracker, an exchange-traded fund (ETF). It would save me a lot of time researching and following individual shares.

Then again, I’d totally miss out on stocks that can go up 10, 20, or even 50 times in value over time. Personally, I’d rather take on more risk for greater potential reward, at least at this stage.

However, when it comes to FTSE trackers, the meagre historical returns have never tempted me to invest. Instead, I’d rather buy individual UK shares that I think can beat the market.

A true FTSE heavyweight

One stock that I think can carry on outperforming is the FTSE 350’s largest constituent: AstraZeneca (LSE: AZN). Shares of the global pharma giant have returned an annualised 10.2% over the past five years, easily beating the FTSE 100’s 6.1%.

In the first half of 2024, the company’s revenue increased 18% year on year to $25.6bn, driven by double-digit growth across all four divisions. Oncology, its largest unit, grew by an impressive 22%.

One risk I do see here is the new US law requiring drugmakers to negotiate prices with the government’s Medicare health insurance programme (covering 66m people). This could impact future earnings.

Still, I think the stock is set up for further gains. AstraZeneca’s pipeline is massive and it’s aiming to launch 20 new medicines by 2030. It’s targeting $80bn in annual revenue by then, up from $45.8bn in 2023.

Plus, I think accelerating advances in artificial intelligence (AI) could revolutionise the industry. The firm is already “embracing the adoption of responsible AI solutions, from discovery to clinical trials, treatment delivery and beyond to bring the right medicines to the right patients, faster than ever before.”

Finally, AstraZeneca’s forward price-to-earnings multiple of 15.3 looks reasonable to me. I’d buy the stock to hold long term if I didn’t already own it.

Ben McPoland has positions in AstraZeneca Plc. The Motley Fool UK has recommended AstraZeneca Plc. Views expressed on the companies mentioned in this article are those of the writer and therefore may differ from the official recommendations we make in our subscription services such as Share Advisor, Hidden Winners and Pro. Here at The Motley Fool we believe that considering a diverse range of insights makes us better investors.

More on Investing Articles

Investing Articles

Down 35% in 2 months! Should I buy NIO stock at $5?

NIO stock has plunged in recent weeks, losing a third of its market value despite surging sales. Is this EV…

Read more »

Two employees sat at desk welcoming customer to a Tesla car showroom
Investing Articles

Could 2026 be the year when Tesla stock implodes?

Tesla's 2025 business performance has been uneven. But Tesla stock has performed well overall and more than doubled since April.…

Read more »

Portrait of elderly man wearing white denim shirt and glasses looking up with hand on chin. Thoughtful senior entrepreneur, studio shot against grey background.
Investing Articles

Could these FTSE 100 losers be among the best stocks to buy in 2026?

In the absence of any disasters, Paul Summers wonders if some of the worst-performing shares in FTSE 100 this year…

Read more »

Midnight is celebrated along the River Thames in London with a spectacular and colourful firework display.
Investing Articles

Up 184% this year, what might this FTSE 100 share do in 2026?

This FTSE 100 share has almost tripled in value since the start of the year. Our writer explains why --…

Read more »

Close-up as a woman counts out modern British banknotes.
Investing Articles

You can save £100 a month for 30 years to target a £2,000 a year second income, or…

It’s never too early – or too late – to start working on building a second income. But there’s a…

Read more »

Hydrogen testing at DLR Cologne
Investing Articles

Forget Rolls-Royce shares! 2 FTSE 100 stocks tipped to soar in 2026

Rolls-Royce's share price is expected to slow rapidly after 2025's stunning gains. Here are two top FTSE 100 shares now…

Read more »

Road 2025 to 2032 new year direction concept
Investing Articles

Brokers think this 83p FTSE 100 stock could soar 40% next year!

Mark Hartley takes a look at the factors driving high expectations for one major FTSE 100 retail stock – is…

Read more »

Investing Articles

I asked ChatGPT for the best FTSE 100 shares to consider for 2026, and it said…

Whatever an individual investor's favourite strategy, I reckon there's something for everyone among the shares in the FTSE 100.

Read more »