Should investors buy AstraZeneca shares after a 16% pullback?

Several recent developments have pushed AstraZeneca shares down. Is this an excellent buying opportunity for long-term investors?

| More on:

The content of this article was relevant at the time of publishing. Circumstances change continuously and caution should therefore be exercised when relying upon any content contained within this article.

Engineer Project Manager Talks With Scientist working on Computer

Image source: Getty Images

You’re reading a free article with opinions that may differ from The Motley Fool’s Premium Investing Services. Become a Motley Fool member today to get instant access to our top analyst recommendations, in-depth research, investing resources, and more. Learn More.

AstraZeneca (LSE: AZN) shares have experienced a sharp pullback. Back in late April, they were trading around the £12.30 mark. Today however, they can be snapped up for about £10.30 – roughly 16% lower.

Is this a great buying opportunity? Let’s discuss.

Why has the share price fallen?

Let’s start by looking at why the share price has fallen. Is there anything we need to be concerned about?

One driver of the weakness here has been proposed drug reforms. Back in late April, the shares took a hit after Brussels published a draft of its proposed overhaul of laws governing the European Union’s pharma industry.

The EU wants to ensure that all Europeans have access to both innovative new treatments and generic drugs. And one of its proposals involves reducing drug market exclusivity for new medicines from 10 years to eight years, after which the market will be opened up to generics.

More recently, the shares dropped in early July after the company announced the results of a Phase III three trial for a new lung cancer drug (datopotamab deruxtecan), which it’s developing with Japan’s Daiichi Sankyo.

AstraZeneca told investors that the drug slowed the progression of lung cancer in the late-stage trial. However, the trial results weren’t as good as some analysts were expecting. Unfortunately, there were some incidences of Grade 5 interstitial lung disease (fatal cases).

It’s worth pointing out that this is one of the big risks when it comes to investing in pharma stocks. When drug trials are successful, investors can do well. However, when trials deliver sub-optimal results, investors can lose money. So shares in this sector can be a little speculative in nature.

A buying opportunity?

Is this a good buying opportunity for long-term investors? I think so.

After the recent pullback, AstraZeneca shares have a forward-looking price-to-earnings (P/E) ratio 18. That’s above the UK market average. But it’s well below the multiples some of its US rivals sport. Eli Lilly, for example, currently has a P/E ratio of about 51.

I think the valuation is very reasonable considering the group is expecting to generate high single-digit to low double-digit percentage earnings growth this year.

The dividend here adds weight to the investment case. AstraZeneca is a reliable dividend payer. And right now, the yield is a healthy 2.3% (again, this is higher than many US rivals).

As for risks, there are a few to be aware of. One is the speculative nature of drug trials I mentioned earlier. AstraZeneca could have further drug setbacks in the future.

Another is the new pharma proposals for Europe. New reforms could impact the company’s revenue growth going forward.

A third risk to consider is lower-than-expected revenues from China. In its Q1 results, the company said it expects revenue from China to return to growth, and increase by a low single-digit percentage in 2023. However, given China’s slow economic recovery, this may not happen.

Overall though, I like the risk/reward set up at the current share price.

Edward Sheldon has no position in any of the shares mentioned. The Motley Fool UK has no position in any of the shares mentioned. Views expressed on the companies mentioned in this article are those of the writer and therefore may differ from the official recommendations we make in our subscription services such as Share Advisor, Hidden Winners and Pro. Here at The Motley Fool we believe that considering a diverse range of insights makes us better investors.

More on Investing Articles

Close-up of British bank notes
Investing Articles

£20,000 for a Stocks and Shares ISA? Here’s how to try and turn it into a monthly passive income of £493

Hundreds of pounds in passive income a month from a £20k Stocks and Shares ISA? Here's how that might work…

Read more »

Snowing on Jubilee Gardens in London at dusk
Investing Articles

£5,000 put into Nvidia stock last Christmas is already worth this much!

A year ago, Nvidia stock was already riding high -- but it's gained value since. Our writer explores why and…

Read more »

Investing Articles

Are Tesco shares easy money heading into 2026?

The supermarket industry is known for low margins and intense competition. But analysts are bullish on Tesco shares – and…

Read more »

Smiling black woman showing e-ticket on smartphone to white male attendant at airport
Investing Articles

Can this airline stock beat the FTSE 100 again in 2026?

After outperforming the FTSE 100 in 2025, International Consolidated Airlines Group has a promising plan to make its business more…

Read more »

Investing Articles

1 Stocks and Shares ISA mistake that will make me a better investor in 2026

All investors make mistakes. The best ones learn from them. That’s Stephen Wright’s plan to maximise returns from his Stocks…

Read more »

Portrait Of Senior Couple Climbing Hill On Hike Through Countryside In Lake District UK Together
Investing Articles

I asked ChatGPT if £20,000 would work harder in an ISA or SIPP in 2026 and it said…

Investors have two tax-efficient ways to build wealth, either in a Stocks and Shares ISA or SIPP. Harvey Jones asked…

Read more »

Investing Articles

How much would I need invested in an ISA to earn £2,417 a month in passive income?

This writer runs the numbers to see what it takes in an ISA to reach £2,417 a month in passive…

Read more »

Investing Articles

Rolls-Royce shares or Melrose Industries: Which one is better value for 2026?

Rolls-Royce shares surged in 2025, surpassing most expectations. Dr James Fox considers whether it offers better value than peer Melrose.

Read more »