Sareum shares just jumped 22%! Here’s why

Sareum shares shot up by 22% in early trading on Wednesday after news emerged about GlaxoSmithKline’s purchase of Sierra Oncology.

| More on:

The content of this article was relevant at the time of publishing. Circumstances change continuously and caution should therefore be exercised when relying upon any content contained within this article.

You’re reading a free article with opinions that may differ from The Motley Fool’s Premium Investing Services. Become a Motley Fool member today to get instant access to our top analyst recommendations, in-depth research, investing resources, and more. Learn More.

Sareum (LSE:SAR) shares jumped by 22% in Wednesday trading. Sareum Holdings is a UK-based pharmaceutical company developing drug candidates, focused on cancer and autoimmune disease.

What’s behind Wednesday’s jump?

Shares in Sareum actually surged again on Wednesday. The share price is up over 130% in the last four days of trading (and 168% in a year). The ongoing rise has partly been driven by the approval of its patent application by the European Patent Office.

On Monday, the European Patent Office granted the firm’s patent application for its SDC-1802 TYK2/JAK1 inhibitor programme. This announcement sent the share price soaring at the time. The patent protects the SDC-1802 molecule and any drugs developed based on the molecule. The discovered molecule is to be used in treating T-cell acute lymphoblastic leukaemia – a type of cancer specific to white blood cells known as T lymphocytes.

But GlaxoSmithKline‘s purchase of Sierra Oncology or $1.9bn (£1.5bn) on Wednesday may have also influenced Sareum’s gains. Sierra Oncology is California-based, late-stage biopharmaceutical company focused on targeted therapies for the treatment of rare forms of cancer. The purchase of Sierra is seen as part of GSK’s transition to focus on its core pharmaceutical business – the Brentford-based firm has also announced the shedding of its consumer health unit.

Sierra has licensed a drug candidate, SRA737, which was discovered and developed by Sareum. It is one of only two assets in Sierra’s pipeline. SRA737 is a novel checkpoint kinase 1 (CHK1) inhibitor. How the takeover will impact the development of it is unknown at this stage.

Earlier in April, shares in the company also rose 18.2% in a single day. No reason was identified for the jump.

Should I buy?

So there is clearly plenty of interest in the stock. But would it make a good buy for me? Sareum made pre-tax losses in each of the last four years. So seemingly its market cap/valuation of £219m at the close of business yesterday is based on future earnings and the value of the products it has discovered and developed. For me, that already sounds a bit risky and I’d need to have a full understanding of the value of those products to justify an investment here.

As I write, the share price is trading at 325p. Last Thursday the stock was trading at under 150p. Those are some considerable gains from a company that hasn’t indicated an increase in profitability. There’s also no concrete evidence that another business might be looking to acquire the company.

As such, Sareum’s valuation is based on the value of its products more than is the case with many other companies. Of course, that brings further risks. For example, it’s entirely possible that another company will discover or develop a more effective way of treating its target disease.

Personally, I think there’s too much risk for me to invest in this one and I won’t be adding it to my portfolio any time soon. That’s not to say the stock won’t continue to soar, it is just not for me.

James Fox has no position in any of the shares mentioned. The Motley Fool UK has no position in any of the shares mentioned. Views expressed on the companies mentioned in this article are those of the writer and therefore may differ from the official recommendations we make in our subscription services such as Share Advisor, Hidden Winners and Pro. Here at The Motley Fool we believe that considering a diverse range of insights makes us better investors.

More on Investing Articles

Investing Articles

Is 2026 the year the Diageo share price bounces back?

Will next year be the start of a turnaround for the Diageo share price? Stephen Wright looks at a key…

Read more »

Investing Articles

Here’s my top FTSE 250 pick for 2026

UK investors looking for under-the-radar opportunities should check out the FTSE 250. And 2026 could be an exciting year for…

Read more »

Yellow number one sitting on blue background
Investing Articles

Here’s my number 1 passive income stock for 2026

Stephen Wright thinks a 5.5% dividend yield from a company with a strong competitive advantage is something passive income investors…

Read more »

Thoughtful man using his phone while riding on a train and looking through the window
Investing Articles

Should I sell my Scottish Mortgage shares in 2026?

After a strong run for Scottish Mortgage shares, our writer wonders if he should offload them to bank profits in…

Read more »

Woman riding her old fashioned bicycle along the Beach Esplanade at Aberdeen, Scotland.
Investing Articles

Down 35%! These 2 blue-chips are 2025’s big losers. But are they the best shares to buy in 2026?

Harvey Jones reckons he's found two of the best shares to buy for the year ahead, but he also acknowledges…

Read more »

A senior man and his wife holding hands walking up a hill on a footpath looking away from the camera at the view. The fishing village of Polperro is behind them.
Investing Articles

State Pension worries? 3 investment trusts to target a £2.6m retirement fund

Royston Wild isn't worried about possible State Pension changes. Here he identifies three investment trusts to target a multi-million-pound portfolio.

Read more »

Smiling white woman holding iPhone with Airpods in ear
Dividend Shares

4 dirt-cheap dividend stocks to consider for 2026!

Discover four great dividend stocks that could deliver long-term passive income -- and why our writer Royston Wild thinks they’re…

Read more »

Young mixed-race woman jumping for joy in a park with confetti falling around her
Investing Articles

These fabulous 5 UK stocks doubled in 2025 – can they do it again next year?

These five UK stocks have more than doubled investors' money as the FTSE 100 surges. Harvey Jones wonders if they…

Read more »