2 FTSE 100 shares I’d buy today

Manika Premsingh thinks FTSE 100 (INDEXFTSE: UKX) giants AstraZeneca plc (LON: AZN) and GlaxoSmithKline plc (LON: GSK) could see further share price increases with healthy results and uncertainty driving investors towards defensives.

| More on:

The content of this article was relevant at the time of publishing. Circumstances change continuously and caution should therefore be exercised when relying upon any content contained within this article.

You’re reading a free article with opinions that may differ from The Motley Fool’s Premium Investing Services. Become a Motley Fool member today to get instant access to our top analyst recommendations, in-depth research, investing resources, and more. Learn More.

Companies can stand out in the equity market by sheer good performance, and sometimes fortune can simply turn in their favour. When the stars well and truly align, both performance and fortune present themselves. Like in the case of FTSE 100 pharmaceutical giants AstraZeneca (LSE: AZN) and GlaxoSmithKline (LSE: GSK).

The big political announcement of the week resulted in a very Brexit-friendly Prime Minister in Boris Johnson, significantly increasing the possibility of a no-deal divorce from the European Union. The resulting uncertainty might be bad for discretionary sectors, but I believe it’s more than likely to drive investors towards defensives, like pharmaceuticals.

The latest results for both companies, also announced during the week, are on point too. Prices of both shares have seen an impressive rise in the past month already and, going by the latest developments, to me it seems that the best is yet to come.

Increasingly optimistic

First, consider AstraZeneca. The results for the first half of 2019 are positive for both sales and profits, to the extent that the company has actually upgraded the sales guidance for the year. I like that the company has reported strong growth in emerging markets, the US and Japan at a time when geographical diversification is the name of the game (in the face of Brexit). The latest numbers only convince me more of the company’s merit.

It was already my top share for May, because of its good results in the first quarter. From then to now the price has risen further by 22%, despite the high price-to-earnings (P/E) ratio. And if the past is any indication of the future, the latest results will only push the price further up over time, even if there are a few corrections along the way.

Positive developments

GSK’s results are also neat, with increases in both sales and profits. I have been quite bullish on the company for a while  for multiple reasons, which continue to hold. Not only is it well on its way to becoming the market leader in consumer healthcare, with the merger with Pfizer, its pharmaceuticals business is looking promising too. It recently announced that its ovarian cancer drug has proven to be effective, which is being seen by analysts as a potential boost for the company.

Strong long-term buys

Even though GSK is priced more reasonably, with a P/E at 21x compared to AstraZeneca’s at 45x, I think both shares merit a place in an investment basket and not just the former. The reason being that AstraZeneca’s meteoric price rise is untouched by its relative expense compared to GSK, because of the positive developments it has seen. I am inclined to see it as a higher price for a share with super positive prospects, even though going purely by the P/E metric, GSK seems the better bet. 

Manika Premsingh has no position in any of the shares mentioned. The Motley Fool UK owns shares of and has recommended GlaxoSmithKline. The Motley Fool UK has recommended AstraZeneca. Views expressed on the companies mentioned in this article are those of the writer and therefore may differ from the official recommendations we make in our subscription services such as Share Advisor, Hidden Winners and Pro. Here at The Motley Fool we believe that considering a diverse range of insights makes us better investors.

More on Investing Articles

Investing Articles

Is 2026 the year the Diageo share price bounces back?

Will next year be the start of a turnaround for the Diageo share price? Stephen Wright looks at a key…

Read more »

Investing Articles

Here’s my top FTSE 250 pick for 2026

UK investors looking for under-the-radar opportunities should check out the FTSE 250. And 2026 could be an exciting year for…

Read more »

Yellow number one sitting on blue background
Investing Articles

Here’s my number 1 passive income stock for 2026

Stephen Wright thinks a 5.5% dividend yield from a company with a strong competitive advantage is something passive income investors…

Read more »

Thoughtful man using his phone while riding on a train and looking through the window
Investing Articles

Should I sell my Scottish Mortgage shares in 2026?

After a strong run for Scottish Mortgage shares, our writer wonders if he should offload them to bank profits in…

Read more »

Woman riding her old fashioned bicycle along the Beach Esplanade at Aberdeen, Scotland.
Investing Articles

Down 35%! These 2 blue-chips are 2025’s big losers. But are they the best shares to buy in 2026?

Harvey Jones reckons he's found two of the best shares to buy for the year ahead, but he also acknowledges…

Read more »

A senior man and his wife holding hands walking up a hill on a footpath looking away from the camera at the view. The fishing village of Polperro is behind them.
Investing Articles

State Pension worries? 3 investment trusts to target a £2.6m retirement fund

Royston Wild isn't worried about possible State Pension changes. Here he identifies three investment trusts to target a multi-million-pound portfolio.

Read more »

Smiling white woman holding iPhone with Airpods in ear
Dividend Shares

4 dirt-cheap dividend stocks to consider for 2026!

Discover four great dividend stocks that could deliver long-term passive income -- and why our writer Royston Wild thinks they’re…

Read more »

Young mixed-race woman jumping for joy in a park with confetti falling around her
Investing Articles

These fabulous 5 UK stocks doubled in 2025 – can they do it again next year?

These five UK stocks have more than doubled investors' money as the FTSE 100 surges. Harvey Jones wonders if they…

Read more »