Is ReNeuron Group plc a better buy than AstraZeneca plc?

Should you ditch AstraZeneca plc (LON: AZN) in favour of ReNeuron Group plc (LON: RENE)?

| More on:

The content of this article was relevant at the time of publishing. Circumstances change continuously and caution should therefore be exercised when relying upon any content contained within this article.

When investing, your capital is at risk. The value of your investments can go down as well as up and you may get back less than you put in.

Read More

The content of this article is provided for information purposes only and is not intended to be, nor does it constitute, any form of personal advice. Investments in a currency other than sterling are exposed to currency exchange risk. Currency exchange rates are constantly changing, which may affect the value of the investment in sterling terms. You could lose money in sterling even if the stock price rises in the currency of origin. Stocks listed on overseas exchanges may be subject to additional dealing and exchange rate charges, and may have other tax implications, and may not provide the same, or any, regulatory protection as in the UK.

You’re reading a free article with opinions that may differ from The Motley Fool’s Premium Investing Services. Become a Motley Fool member today to get instant access to our top analyst recommendations, in-depth research, investing resources, and more. Learn More.

sdf

Shares in healthcare company ReNeuron (LSE: RENE) have risen by over 4% today after it released an encouraging trading update. It shows that the company is making good progress with its strategy, which is providing tangible results according to a further announcement made by the company today. Does this mean that it worth buying ahead of larger healthcare peer AstraZeneca (LSE: AZN)?

Upbeat progress

ReNeuron’s update includes information regarding the outcome of a Phase II clinical trial for its CTX cell therapy candidate for stroke disability. It showed positive results, with three of the 21 patients reporting a two-point or more increase in a grasping and lift test at three months post-treatment.

This was ahead of the target of two patients achieving that goal. The company will now continue with an application in the US and Europe for a pivotal clinical trial in patients living with disability post-stroke.

This is a significant milestone for the company and shows that its treatment has the potential to meet at least some of the high demand for treatments for chronic stroke disability. Clearly, there’s still some way to go in this endeavour, but it’s moving in the right direction.

Furthermore, ReNeuron announced positive news regarding the Phase I/II clinical trial of its hRPC cell therapy candidate. Its therapeutic programmes remain well-funded and it’s on target to meet its medium-term milestones at the present time.

Future potential

Clearly, ReNeuron has a bright long-term future. However, it remains a relatively small business, which is reliant on a smaller number of potential treatments than a sector peer such as AstraZeneca. Its larger peer has a more diversified pipeline so that if a potential treatment disappoints at a clinical trial, the company’s long-term future isn’t staked on it. As a result of this, AstraZeneca offers a much lower risk profile than ReNeuron.

Furthermore, AstraZeneca is on the cusp of improved financial performance following a major acquisition programme. It has been able to leverage a sound balance sheet and strong cash flow to make multiple purchases in recent years. This will see the company eventually replace the former blockbuster drugs that are now under threat from generics due to a loss of patents.

So, while AstraZeneca is expected to record a fall in profitability over the next couple of years, its longer-term future is much brighter. And with it trading on a price-to-earnings (P/E) ratio of 12, it offers excellent value for money.

As such, it offers lower risk than ReNeuron, as well as the potential for high rewards in the long run. Certainly, ReNeuron may prove to be a sound buy for less risk-averse investors and its share price is likely to move higher following today’s positive update. But for risk-averse investors, AstraZeneca remains the more appealing choice.

Should you invest, the value of your investment may rise or fall and your capital is at risk. Before investing, your individual circumstances should be assessed. Consider taking independent financial advice.

Peter Stephens owns shares of AstraZeneca. The Motley Fool UK has recommended AstraZeneca. We Fools don't all hold the same opinions, but we all believe that considering a diverse range of insights makes us better investors.

More on Investing Articles

Young Asian man drinking coffee at home and looking at his phone
Investing Articles

Here’s a dirt-cheap FTSE 100 share to consider before it surges again!

This FTSE 100 share may have doubled in value in 2025. But as Royston Wild explains, it still looks like…

Read more »

Man thinking about artificial intelligence investing algorithms
Investing Articles

Can I buy Cathie Wood’s ARK Innovation ETF for my ISA or SIPP?

The ARK Innovation ETF is a US investment fund. Can the product be bought for an Individual Savings Account or…

Read more »

Little girl helping her Grandad plant tomatoes in a greenhouse in his garden.
Investing Articles

Lloyds shares: here’s the latest price and dividend forecasts

Harvey Jones is thrilled with the total return from his Lloyds shares. Now he examines whether they can keep serving…

Read more »

Investing Articles

Up 50% and 30% in a year! These 2 FTSE 100 dividend shares are behaving like growth stocks

When dividend shares deliver growth as well, investors are in luck. These two FTSE 100 shares are best known for…

Read more »

Middle aged businesswoman using laptop while working from home
Investing Articles

2 stocks every passive income seeker should know about

Dividend shares can be great sources of passive income. Stephen Wright likes the look of two that have fallen out…

Read more »

Mature black woman at home texting on her cell phone while sitting on the couch
Dividend Shares

I asked ChatGPT for the best FTSE 250 stocks for passive income, with these results!

Jon Smith asks his AI friend for advice regarding passive income options, but doesn't agree with all the results that…

Read more »

A handsome mature bald bearded black man in a sunglasses and a fashionable blue or teal costume with a tie is standing in front of a wall made of striped wooden timbers and fastening a suit button
Investing Articles

Want to make a million from penny shares? Here’s 1 way to try

Investors wanting to build up a potential millionaire portfolio with diversified penny shares might want to consider adding this one.

Read more »

Businessman using pen drawing line for increasing arrow from 2024 to 2025
Investing Articles

Want to turn a £20k ISA into a £1m portfolio? Here’s how

Dr James Fox explains the strategy many investors employ when trying to turn their ISA into a life-changing pot of…

Read more »