Is ReNeuron Group plc a better buy than AstraZeneca plc?

Should you ditch AstraZeneca plc (LON: AZN) in favour of ReNeuron Group plc (LON: RENE)?

| More on:

The content of this article was relevant at the time of publishing. Circumstances change continuously and caution should therefore be exercised when relying upon any content contained within this article.

You’re reading a free article with opinions that may differ from The Motley Fool’s Premium Investing Services. Become a Motley Fool member today to get instant access to our top analyst recommendations, in-depth research, investing resources, and more. Learn More.

Shares in healthcare company ReNeuron (LSE: RENE) have risen by over 4% today after it released an encouraging trading update. It shows that the company is making good progress with its strategy, which is providing tangible results according to a further announcement made by the company today. Does this mean that it worth buying ahead of larger healthcare peer AstraZeneca (LSE: AZN)?

Upbeat progress

ReNeuron’s update includes information regarding the outcome of a Phase II clinical trial for its CTX cell therapy candidate for stroke disability. It showed positive results, with three of the 21 patients reporting a two-point or more increase in a grasping and lift test at three months post-treatment.

This was ahead of the target of two patients achieving that goal. The company will now continue with an application in the US and Europe for a pivotal clinical trial in patients living with disability post-stroke.

This is a significant milestone for the company and shows that its treatment has the potential to meet at least some of the high demand for treatments for chronic stroke disability. Clearly, there’s still some way to go in this endeavour, but it’s moving in the right direction.

Furthermore, ReNeuron announced positive news regarding the Phase I/II clinical trial of its hRPC cell therapy candidate. Its therapeutic programmes remain well-funded and it’s on target to meet its medium-term milestones at the present time.

Future potential

Clearly, ReNeuron has a bright long-term future. However, it remains a relatively small business, which is reliant on a smaller number of potential treatments than a sector peer such as AstraZeneca. Its larger peer has a more diversified pipeline so that if a potential treatment disappoints at a clinical trial, the company’s long-term future isn’t staked on it. As a result of this, AstraZeneca offers a much lower risk profile than ReNeuron.

Furthermore, AstraZeneca is on the cusp of improved financial performance following a major acquisition programme. It has been able to leverage a sound balance sheet and strong cash flow to make multiple purchases in recent years. This will see the company eventually replace the former blockbuster drugs that are now under threat from generics due to a loss of patents.

So, while AstraZeneca is expected to record a fall in profitability over the next couple of years, its longer-term future is much brighter. And with it trading on a price-to-earnings (P/E) ratio of 12, it offers excellent value for money.

As such, it offers lower risk than ReNeuron, as well as the potential for high rewards in the long run. Certainly, ReNeuron may prove to be a sound buy for less risk-averse investors and its share price is likely to move higher following today’s positive update. But for risk-averse investors, AstraZeneca remains the more appealing choice.

Peter Stephens owns shares of AstraZeneca. The Motley Fool UK has recommended AstraZeneca. We Fools don't all hold the same opinions, but we all believe that considering a diverse range of insights makes us better investors.

More on Investing Articles

Young Caucasian man making doubtful face at camera
Dividend Shares

Down 24% in 10 months, Greggs shares are baking bad!

After a turbulent 2025, Greggs shares continue to bounce around this year. But with the stock trading at levels seen…

Read more »

Asian man looking concerned while studying paperwork at his desk in an office
Investing Articles

A stock market crash feels like it might be imminent

Conflict in the Middle East means a stock market crash feels like a real possibility right now. But being ready…

Read more »

Rolls-Royce's Pearl 10X engine series
Investing Articles

Should I buy Rolls-Royce shares as they march ever higher?

Rolls-Royce is making billions of pounds a year and looks set to do even better in future -- so what's…

Read more »

Smiling family of four enjoying breakfast at sunrise while camping
Investing Articles

£1,000 buys 110 shares in this UK beverage stock that’s smashing Diageo 

Shares of Tanqueray-maker Diageo are languishing at multi-year lows. So why is the stock behind this tonic water brand on…

Read more »

UK financial background: share prices and stock graph overlaid on an image of the Union Jack
Investing Articles

What next for Aviva shares after a cracking set of 2025 results?

Aviva achieving its 2026 financial goals a year ahead of schedule has got to be good for the shares... oh,…

Read more »

This way, That way, The other way - pointing in different directions
Investing Articles

Should I buy stocks or look to conserve cash right now?

In a market dealing with AI uncertainty and conflict in the Middle East, should investors be looking for stocks to…

Read more »

Investing Articles

Here’s how many British American Tobacco shares it takes to earn a £1,000 monthly second income

Is an AI-resistant business with a 5.38% dividend yield a good choice for investors looking for a second income in…

Read more »

Black woman using smartphone at home, watching stock charts.
Investing Articles

1,001 Barclays shares bought 12 months ago are now worth…

Barclays shares have delivered excellent returns over the last year. But can the FTSE 100 bank keep outperforming? Royston Wild…

Read more »