Share your opinion and earn yourself a free Motley Fool premium report!

We are looking for Fools to join a 75 minute online independent market research forum on 15th / 16th December.

To find out more and express your interest please click here

What does AstraZeneca plc’s deal with Pfizer mean for shareholders?

Should you buy, sell or hold AstraZeneca plc (LON: AZN) after the company’s Pfizer deal?

| More on:

The content of this article was relevant at the time of publishing. Circumstances change continuously and caution should therefore be exercised when relying upon any content contained within this article.

You’re reading a free article with opinions that may differ from The Motley Fool’s Premium Investing Services. Become a Motley Fool member today to get instant access to our top analyst recommendations, in-depth research, investing resources, and more. Learn More.

More than a year after Pfizer approached AstraZeneca (LSE: AZN) about a potential merger, the US pharmaceutical giant has returned to do a deal with its UK counterpart. 

The deal is perhaps smaller than many investors would have liked with Pfizer agreeing to pay $550m upfront for Astra’s small molecule antibiotics business. It seems that for now at least, Pfizer is content with owning just part of Astra, rather than the whole company. 

Still, the deal could give Astra a much-needed cash boost over the next few years. In total, it could net the company $1.6bn through a combination of staggered payments and royalties. As well as the $550m upfront, the US company will pay an unconditional $175m in January 2019. 

The deal includes three already-approved antibiotics, Merrem, Zinforo and Zavicefta, and two drugs in clinical trials. Depending on the progress of these treatments, Pfizer will pay Astra a further $850m on top of the upfront payment. 

The market’s reaction to this deal doesn’t instil confidence. Shares in Astra are trading down by nearly 1% in early deals.

Approach with caution 

The market’s cautious reaction to today’s announcement is understandable. Astra is facing a massive headwind in the form of patent expirations this year and so far it looks as if the company’s only action to stem revenue declines is to sell off the family silver.

Indeed, so-called externalisation deals have become a key part of the company’s drive to boost sales. The deals involve selling some of the future upside in Astra’s drugs for one-off payments. These deals are by their very nature one-off, but Astra is using them as a key revenue stream. Last year these one-time gains accounted for some $2.5bn of Astra’s $5.5bn of operating profits. Long term this gamble by management may pay off but there’s no denying that Astra is sugar-coating short-term profits.

Today’s deal with Pfizer seems to be another attempt by management to sell off drugs for a one-off income boost. 

Barring today’s deal, the bigger concern for Astra’s shareholders is how quickly the company’s sales decline after Crestor, Astra’s best-selling treatment comes off patent. The substance patent for Crestor expired, on 8 July, a week after the end of Astra’s Q2, so as of yet, investors have no idea how the company is faring in the new environment. The patent was set to expire at the beginning of January, but AstraZeneca won a six-month extension under the US paediatric trials incentive programme. 

The bottom line 

Overall, today’s deal with Pfizer isn’t a game-changer for Astra. While management will welcome the additional cash, until the full impact of Astra’s loss of exclusive manufacturing rights for Crestor is known, the market will likely view the company with caution. 

City analysts expect Astra to report a 5% decline in EPS for 2016. Based on these forecasts the company is trading at a forward P/E of 16.5 and the shares support a dividend yield of 4.2%.

Rupert Hargreaves has no position in any shares mentioned. The Motley Fool UK has recommended AstraZeneca. We Fools don't all hold the same opinions, but we all believe that considering a diverse range of insights makes us better investors.

More on Investing Articles

Black woman using smartphone at home, watching stock charts.
US Stock

I asked ChatGPT for the juiciest growth share for 2026, and it said…

Jon Smith is rather unimpressed with the growth share that ChatGPT presents to him, and explains his reasons why in…

Read more »

Two business people sitting at cafe working on new project using laptop. Young businesswoman taking notes and businessman working on laptop computer.
Dividend Shares

Here’s a stock lurking in the FTSE 100 with a 9% dividend yield forecast

Jon Smith highlights a FTSE 100 company that he thinks has been in the headlights for share price growth recently…

Read more »

Bus waiting in front of the London Stock Exchange on a sunny day.
Investing Articles

Could a 2026 stock market crash be on its way?

Will the stock market crash next year? Nobody knows for sure, including our writer. Here's what he's doing now to…

Read more »

Thoughtful man using his phone while riding on a train and looking through the window
Investing Articles

How much do you need in an ISA to target a £5,555 monthly passive income?

Muhammad Cheema explains how an investor could target £5,555 in monthly passive income over time by making use of a…

Read more »

Little girl helping her Grandad plant tomatoes in a greenhouse in his garden.
Investing Articles

With single-digit P/E ratios, here are 3 of the FTSE 100’s cheapest-looking shares!

Only a few FTSE 100 shares are trading at single digit-multiples of earnings! And our Foolish author has highlighted what…

Read more »

Friends at the bay near the village of Diabaig on the side of Loch Torridon in Wester Ross, Scotland. They are taking a break from their bike ride to relax and chat. They are laughing together.
Investing Articles

How much do you need in an ISA to earn a £33,333 passive income?

Discover how to target a five-figure passive income in a Stocks and Shares ISA -- and a top 7.6%-yielding dividend…

Read more »

Tariffs and Global Economic Supply Chains
Investing Articles

Did Donald Trump just deliver fantastic news for Nvidia stock?

With artificial intelligence chip sales set to resume in China, is Nvidia stock worth looking at while it's trading under…

Read more »

A rear view of a female in a bright yellow coat walking along the historic street known as The Shambles in York, UK which is a popular tourist destination in this Yorkshire city.
Market Movers

£20,000 of British American Tobacco shares could generate dividends of…

British American Tobacco shares are tipped to deliver more huge dividends over the next three years. Does this make them…

Read more »