Should you buy into the pharma boom with GlaxoSmithKline plc and Shire plc?

Healthcare companies GlaxoSmithKline plc (LON: GSK) and Shire plc (LON: SHP) are both worth a closer look.

The content of this article was relevant at the time of publishing. Circumstances change continuously and caution should therefore be exercised when relying upon any content contained within this article.

You’re reading a free article with opinions that may differ from The Motley Fool’s Premium Investing Services. Become a Motley Fool member today to get instant access to our top analyst recommendations, in-depth research, investing resources, and more. Learn More.

Visit the science laboratory of any pharmaceutical company, or the labs of one of the world’s leading universities, and you’ll be amazed by the quality and diversity of the research being undertaken there.

Scientists will be trying to determine how proteins fold and how they interact with cell membranes. Geneticists will be unravelling the secrets of our DNA, and will be developing stem cell therapies that will transform the world of medicine. And researchers will be designing antibodies to combat diseases such as cancer and arthritis.

The pharmaceutical industry has faced plenty of naysayers who’ve argued that it’s in decline, that earnings will fall and that investors should avoid this industry. But just as those who said that television would decline with the rise of the internet were proved wrong, so I think the pharma sector will prove its critics wrong.

And in this article I’ll present two visions of the future of the drugs industry: GlaxoSmithKline (LSE: GSK) and Shire (LSE: SHP).

GlaxoSmithKline

There’s been much talk in recent years of GlaxoSmithKline’s drugs pipeline. There have been several medicine launches in recent years, yet none has turned into a blockbuster to match the success of treatments like Zantac. Yet I see this company’s strength not as its drugs pipeline, but instead the breadth of products that it offers, and the range of regions it serves.

GSK produces a wide variety of prescription medicines, some under patent, and many now off patent. Alongside this, it has a very substantial consumer healthcare range, including brands such as Voltaren, Sensodyne, Panadol and Nicorette.

What’s more, the firm has a growing vaccines business, and is the global leader in HIV/AIDS treatments.

And it’s taking this wide portfolio of products to clinics, pharmacies and supermarkets around the world. I expect this multi-pronged strategy to drive earnings gradually higher. A 2016 P/E ratio of 15.81 and a dividend yield of 5.77% means this company is very reasonably priced, and a recently sliding valuation means it may be a good time to buy.

Shire

Shire is a unique drugs business in that it uses highly focused research and in-depth knowledge of a range of rare diseases to produce effective treatments. It’s really a cluster of small biotech companies. In the past, such niche treatments would be so expensive as to be unaffordable, or wouldn’t merit the research and development spend required.

But by combining these biotech start-ups and pooling resources, a much larger company can be formed that has larger marketing and research budgets.

It’s a very clever way to run a drugs firm, and it has been working in spades. Earnings per share are expected to jump from 148.76p in 2013 to 350.91p in 2017, yet a pull-back in the stock price means that the 2016 P/E ratio is just 13.92, with a dividend yield of 0.38%.

If GSK is a dividend play, Shire is a growth company that may eventually mature into a high yielder. I feel both are worth a closer look.

Prabhat Sakya has no position in any shares mentioned. The Motley Fool UK owns shares of and has recommended GlaxoSmithKline. We Fools don't all hold the same opinions, but we all believe that considering a diverse range of insights makes us better investors.

More on Investing Articles

Investing Articles

Is Alphabet still one of the best shares to buy heading into 2026?

The best time to buy shares is when other investors are seeing risks. Is that the case with Google’s parent…

Read more »

Investing Articles

Could the Barclays share price be the FTSE 100’s big winner in 2026?

With OpenAI and SpaceX considering listing on the stock market, could investment banking revenues push the Barclays share price higher…

Read more »

Investing Articles

Will the Nvidia share price crash in 2026? Here are the risks investors can’t ignore

Is Nvidia’s share price in danger in 2026? Stephen Wright outlines the risks – and why some might not be…

Read more »

Middle-aged white man pulling an aggrieved face while looking at a screen
Growth Shares

I asked ChatGPT how much £10,000 invested in Lloyds shares 5 years ago is worth today? But it wasn’t very helpful…

Although often impressive, artificial intelligence has its flaws. James Beard found this out when he used it to try and…

Read more »

Portrait of pensive bearded senior looking on screen of laptop sitting at table with coffee cup.
Investing Articles

Did ChatGPT give me the best FTSE stocks to buy 1 year ago?

ChatGPT can do lots of great stuff, but is it actually any good at identifying winning stocks from the FTSE…

Read more »

Surprised Black girl holding teddy bear toy on Christmas
Investing Articles

Who will be next year’s FTSE 100 Christmas cracker?

As we approach Christmas 2025, our writer identifies the FTSE 100’s star performer this year. But who will be number…

Read more »

Businessman with tablet, waiting at the train station platform
Investing Articles

I asked ChatGPT for an 8%-yielding passive income portfolio of dividend shares and it said…

Mark Hartley tested artificial intelligence to see if it understood how to build an income portfolio from dividend shares. He…

Read more »

Female student sitting at the steps and using laptop
Investing Articles

How much do you need in an ISA to target £8,333 a month of passive income?

Our writer explores a potential route to earning double what is today considered a comfortable retirement and all tax-free inside…

Read more »