GlaxoSmithKline plc or AstraZeneca plc? Which Drugs Giant Should You Buy?

Bilaal Mohamed analyses the investment potential of GlaxoSmithKline plc (LON: GSK) & AstraZeneca plc (LON: AZN). Which giant will best help your portfolio hit the big time?

| More on:

The content of this article was relevant at the time of publishing. Circumstances change continuously and caution should therefore be exercised when relying upon any content contained within this article.

You’re reading a free article with opinions that may differ from The Motley Fool’s Premium Investing Services. Become a Motley Fool member today to get instant access to our top analyst recommendations, in-depth research, investing resources, and more. Learn More.

When it comes to ‘Big Pharma’, they don’t come any bigger than GlaxoSmithKline (LSE: GSK) and AstraZeneca (LSE: AZN) – well in the UK at least. Valued at around £68bn and £50bn, respectively, they’re both more than twice the size of the only other FTSE 100 listed pharmaceutical company Shire plc (LSE: SHP). So which is the best investment?

Joint venture boost

GlaxoSmithKline is one of the world’s leading pharmaceutical research companies. The company was created out of the merger between GlaxoWellcome and SmithKline Beecham in 2000 to create one of the UK’s largest listed companies, and the country’s most gigantic drugs giant.

Glaxo’s full year results announced last month revealed an increase in revenues to £24bn, up from £23bn, and a sharp rise in pre-tax profits to £10.5bn, up from £3bn the previous year. This was mainly due to its deal with Swiss pharmaceutical giant Novartis, where Glaxo sold cancer drugs, acquired a vaccines business and set up a joint venture in consumer healthcare.

The outlook for the firm looks good, with our friends in the City expecting earnings to rise by 13% this year, followed by a further improvement of 6% earmarked for 2017. Dividends are forecast at 82.03p per share for this year, falling slightly to 80.36p next year, offering prospective yields of 5.9% and 5.8% for the next two years.

Glaxo trades on 16 times forecast earnings for this year, falling to 15 for the year ending 31 December 2017. That may not make them a bargain but the shares look fairly priced given the earnings outlook, while the strong dividend and defensive qualities should tempt income investors.

Losing its patents

AstraZeneca is another leading pharmaceuticals group created by a merger, in this case the 1999 merger of Sweden’s Astra and the UK’s Zeneca, which had itself been de-merged from chemicals group ICI in 1993.

Astra has its problems. Announcing its annual results last month, the company reported a 7% drop in revenues to $24.7bn as sales of its major drugs slowed due to generic competition. And while pre-tax profits were up from $1.2bn to $3bn, this was mostly as a result of cost-cutting.

Astra faces a tough year ahead too with the patent for its most important drug, the anti-cholesterol statin Crestor, expiring in May. Consequently, analysts in the Square Mile expect earnings to be 5% lower this year, with a further 1% decline pencilled-in for 2017. But dividends are forecast at 193.59p per share for this year, rising slightly to 194.15p next year, offering prospective yields of 5% for the next couple of years.

AstraZeneca trades on 14 times forecast earnings for this year, rising slightly to 14.1 for the year ending 31 December 2017. The firm’s P/E rating is moderate and on a par with GlaxoSmithKline, but the shares offer a strong dividend that should be attractive to income hunters, despite the firm’s challenges.

What next?

In my opinion Glaxo edges past Astra given the stronger earnings outlook and slightly higher dividend yield. So which should you buy?  How about both? Each continues to offer strong defensive qualities and healthy income, which is why many UK-based portfolios have either or both of these pharmaceutical giants as core holdings.

Bilaal Mohamed has no position in any shares mentioned. The Motley Fool UK has recommended AstraZeneca and GlaxoSmithKline. We Fools don't all hold the same opinions, but we all believe that considering a diverse range of insights makes us better investors.

More on Investing Articles

British flag, Big Ben, Houses of Parliament and British flag composition
Investing Articles

Back above 10,000! Is the FTSE 100 index on track again?

The FTSE 100 index has been yo-yoing up and down with the latest news headlines around the oil crisis. Where…

Read more »

Finger clicking a button marked 'Buy' on a keyboard
Investing Articles

Stock market correction: Is there still time to buy UK shares cheap?

Long-term investors can do well to stay calm through stock market corrections, and even crashes, and pick up shares when…

Read more »

Warm summer evening outside waterfront pubs and restaurants at the popular seaside resort town of Weymouth, Dorset.
Investing Articles

2 FTSE 100 blue-chips to consider for a new £20k Stocks and Shares ISA

Ben McPoland highlights a pair of high-quality FTSE 100 stocks that have strong momentum on their side yet are trading…

Read more »

Young Caucasian woman with pink her studying from her laptop screen
Investing Articles

Are depressed Lloyds shares just too tempting to miss now?

Lloyds shares are coming under renewed pressure as conflict in the Middle East threatens the fragile global economic recovery.

Read more »

Female student sitting at the steps and using laptop
Investing Articles

7 FTSE 100 shares that look cheap after the 2026 stock market correction

Falling stock markets often present bargain opportunities. Let's take a look at some of the cheapest FTSE 100 shares at…

Read more »

piggy bank, searching with binoculars
US Stock

Up 59% this year, this S&P 500 stock is smashing the index!

Jon Smith points out a stock from the S&P 500 that's flying right now as part of a transformation plan,…

Read more »

Businessman hand stacking money coins with virtual percentage icons
Investing Articles

Stock market correction: a rare second income opportunity?

Falling share prices are pushing dividend yields higher. That makes it a good time for investors looking for chances to…

Read more »

Finger clicking a button marked 'Buy' on a keyboard
Dividend Shares

I just discovered this REIT with a juicy 9% dividend yield

Jon Smith points out a REIT that just came on his radar due to the high yield, but comes with…

Read more »