AstraZeneca: why I’m forgetting the headlines and following the trendlines

AstraZeneca is forging ahead with its portfolio of ‘on trend’ medicines that should prove increasingly profitable.

| More on:

The content of this article was relevant at the time of publishing. Circumstances change continuously and caution should therefore be exercised when relying upon any content contained within this article.

When investing, your capital is at risk. The value of your investments can go down as well as up and you may get back less than you put in.

Read More

The content of this article is provided for information purposes only and is not intended to be, nor does it constitute, any form of personal advice. Investments in a currency other than sterling are exposed to currency exchange risk. Currency exchange rates are constantly changing, which may affect the value of the investment in sterling terms. You could lose money in sterling even if the stock price rises in the currency of origin. Stocks listed on overseas exchanges may be subject to additional dealing and exchange rate charges, and may have other tax implications, and may not provide the same, or any, regulatory protection as in the UK.

You’re reading a free article with opinions that may differ from The Motley Fool’s Premium Investing Services. Become a Motley Fool member today to get instant access to our top analyst recommendations, in-depth research, investing resources, and more. Learn More.

AstraZeneca (LSE:AZN) has spent the last few weeks being ground between the gears of the European Union’s political machine amidst geopolitical rows over vaccine supplies.  One cannot but help feel a little sorry for the FTSE 100 stalwart given its commitment to supply its ADZ1222 vaccine at cost price for the duration of the pandemic.  Since the company will not profit from ADZ1222, one might have expected that AstraZeneca would at least have enjoyed the kind of adoring publicity that has sent other pharma share prices soaring.

Whilst the share prices of pharmaceutical companies such as Moderna have appreciated by a factor of ten during the last 52 weeks thanks to developing a Covid-19 vaccine, AstraZeneca’s has remained grounded and today is at the same level that it was in mid-2019. 

But the truth is that whilst the media headlines are focused on Covid-19 vaccines, many of which will yield no profit and all of which will face stiff competition as more new vaccines are approved, AstraZeneca is forging ahead with its portfolio of ‘on trend’ medicines that should prove increasingly profitable as they propagate into wider clinical use.  This portfolio of medicines represents an upside which seems to be barely priced into the current shares.

Take AZD7442 as an example.  It is an antibody combination medicine that could prevent people who are not a candidate for the COVID-19 vaccine from catching the virus for a period of six to twelve months.  AZD7442 may also enhance the immune systems of people who have caught Covid-19, and so potentially improve individual survival rates.  An analysis by Morgan Stanley suggests that AZD7442 alone could boost AstraZeneca profits by 30% in 2021.

AstraZeneca has also been churning out game-changing new medicines for the treatment of cancers at an impressive rate, which grew revenues in its oncology portfolio by 24% in 2020.  Oncology is one of the biggest areas of pharma investment, and AstraZeneca owns some of the best new medicines for treating cancers.  The company’s future pipeline also includes 172 projects and nine new drugs that are currently in late-stage trials.  Taken together, this emphasises the company’s entrenched position as a global leader in oncology medicine.

Some investors have worried that plans to acquire Alexion Pharmaceuticals for $39 billion will be a false step by AstraZeneca.  Such mega-mergers rarely manage to create the kind of new shareholder value that they initially promise.  But the acquisition will likely create a new area of strength for the company in the highly profitable rare diseases space, and AstraZeneca says that Alexion’s cash flow will enable it to increase its R&D spending.

But for all of this analysis, my sentiment that AstraZeneca is a good long-term investment comes down so a fairly simple calculus: that the company already occupies a strong position and is doing some truly ground-breaking things which, in better times, would illicit a lot more excitement from the investment community.  At today’s price of 7,334p, I believe there is approximately 40% of upside if shares in AstraZeneca simply return to their 52-week high of 10,120p, and in terms of risk, the company is about as blue chip as things can get.

There will be other stocks that might appear to offer a better yield or equity growth over the next few years, but I cannot think of many stocks that can rival AstraZeneca right now in being able to offer so much upside investment potential for such a low level of risk.


Should you invest, the value of your investment may rise or fall and your capital is at risk. Before investing, your individual circumstances should be assessed. Consider taking independent financial advice.

Tej Kohli owns shares in AstraZeneca and Moderna. The Motley Fool UK has no position in any of the shares mentioned. Views expressed on the companies mentioned in this article are those of the writer and therefore may differ from the official recommendations we make in our subscription services such as Share Advisor, Hidden Winners and Pro. Here at The Motley Fool we believe that considering a diverse range of insights makes us better investors.

Tej Kohli is the founder of the philanthropic Tej Kohli Foundation whose ‘Rebuilding You’ philosophy supports the development of scientific and technological solutions to major global health challenges, whilst also making direct interventions to rebuild individuals and communities around the world. Tej Kohli is also an investor who backs growth-stage artificial intelligence and robotics ventures through the Kohli Ventures investment vehicle.

More on Investing Articles

Investing Articles

3 shares I’d buy for passive income if I was retiring early

Roland Head profiles three FTSE 350 dividend shares he’d like to buy for their passive income to support an early…

Read more »

Investing Articles

Here’s how many Aviva shares I’d need for £1,000 a year in passive income

Our writer has been buying shares of this FTSE 100 insurer, but how many would he need to aim for…

Read more »

Female Doctor In White Coat Having Meeting With Woman Patient In Office
Investing Articles

1 incredible growth stock I can’t find on the FTSE 100

The FTSE 100 offers us a lot of interesting investment opportunities, but there's not much in the way of traditional…

Read more »

Mature Caucasian woman sat at a table with coffee and laptop while making notes on paper
Investing Articles

With an £8K lump sum, I could create an annual second income worth £5,347

This Fool explains how a second income is achievable by using a lump sum, investing in stocks, and the magic…

Read more »

Investing Articles

Here’s what dividend forecasts could do for the BT share price in the next 3 years

With the BT share price down so low, the dividend looks very nice indeed. The company's debt is off-putting, though.…

Read more »

Hand of person putting wood cube block with word VALUE on wooden table
Investing Articles

28% revenue growth per year and down over 20% in price! Should I invest in this niche FTSE 250 company?

Oliver says this FTSE 250 company has done an excellent job bringing auctioning into the modern world. Will he invest…

Read more »

Investing Articles

After gaining over 200% in 12 months, what’s next for Nvidia stock?

Oliver thinks Nvidia stock could be as enduring an investment as Amazon. Even given the valuation risks, he says he…

Read more »

Passive income text with pin graph chart on business table
Investing Articles

With a 6.7% yield, I consider Verizon exceptional for passive income

Oliver Rodzianko says Verizon offers one of the best passive income opportunities on the market. He just needs to remember…

Read more »