Should you buy or sell the GSK share price?

Roland Head explains why big changes could make GlaxoSmithKline plc (LON: GSK) a compelling buy.

The content of this article was relevant at the time of publishing. Circumstances change continuously and caution should therefore be exercised when relying upon any content contained within this article.

You’re reading a free article with opinions that may differ from The Motley Fool’s Premium Investing Services. Become a Motley Fool member today to get instant access to our top analyst recommendations, in-depth research, investing resources, and more. Learn More.

The GlaxoSmithKline (LSE: GSK) share price has beaten the market over the last five years, climbing 14% against a gain of less than 5% for the FTSE 100.

Since chief executive Emma Walmsley took charge in March 2017, she’s put in place a series of big changes that will lead to a completely reshaped business. As a shareholder myself, I feel good about the outlook for the business and believe these changes have made the stock much more attractive for new investors.

Big changes

When Walmsley took over as CEO, she appeared to support Glaxo’s conglomerate structure, which included pharmaceuticals, consumer healthcare products, and brands such as Horlicks.

At some point, Walmsley’s position changed. Horlicks has been sold to Unilever and the group’s consumer healthcare and pharmaceutical businesses are heading for a split by late 2022. Ahead of this split, both the pharma and consumer sides of the business are being bolstered by acquisitions to strengthen their long-term prospects.

US firm pharma Tesaro, which is focused on cancer treatments, was added to the Glaxo portfolio earlier this year for $5.1bn. In parallel with this, Walmsley agreed a series of deals with rivals Novartis and Pfizer that will significantly enlarge GSK’s consumer healthcare division.

With both parts of the business suitably reinforced, the stage has been set for Glaxo to split itself at some point in the next three years.

Why I think this is good news

Why do I think that splitting GSK into two will be good for shareholders? Two reasons. The first is that history suggests two smaller, more focused businesses perform better and attract higher valuations. That should be good for GSK shareholders, who will receive shares in the new consumer business.

The second reason I’m keen is that the split should help to solve Glaxo’s debt problem. The consumer healthcare business should benefit from predictable cash flows and stable profit margins. It should comfortably be able to take on a significant share of the group’s £29bn net debt. This should leave the pharma business with a stronger balance sheet and more flexibility to invest in new opportunities.

Focus on the numbers

Looking back at Glaxo’s accounts since 2016, I can see a clear pattern of improving profitability and stronger cash flow. My sums indicate GlaxoSmithKline’s operating profit margin has risen from a low of 9.3% in 2016 to 20.1% over the last 12 months.

Return on capital employed, which compares operating profit with capital invested in the business, has risen from 6.5% to 16.9% over the same period. In my view these are attractive figures which suggest the CEO has spent money wisely, and is returning the business to growth.

Is now the right time to buy GSK?

Glaxo’s rising share price means this stock isn’t quite as cheap as it was a few months ago. However, for long-term investors, I think the valuation remains attractive.

At the time of writing, GSK shares were trading on 14.6 times 2019 forecast earnings, with a dividend yield of 4.8%. I think that’s a reasonable starting point and would continue to rate Glaxo shares a ‘buy’.

Roland Head owns shares of GlaxoSmithKline. The Motley Fool UK owns shares of and has recommended GlaxoSmithKline. Views expressed on the companies mentioned in this article are those of the writer and therefore may differ from the official recommendations we make in our subscription services such as Share Advisor, Hidden Winners and Pro. Here at The Motley Fool we believe that considering a diverse range of insights makes us better investors.

More on Investing Articles

Investing Articles

Is 2026 the year the Diageo share price bounces back?

Will next year be the start of a turnaround for the Diageo share price? Stephen Wright looks at a key…

Read more »

Investing Articles

Here’s my top FTSE 250 pick for 2026

UK investors looking for under-the-radar opportunities should check out the FTSE 250. And 2026 could be an exciting year for…

Read more »

Yellow number one sitting on blue background
Investing Articles

Here’s my number 1 passive income stock for 2026

Stephen Wright thinks a 5.5% dividend yield from a company with a strong competitive advantage is something passive income investors…

Read more »

Thoughtful man using his phone while riding on a train and looking through the window
Investing Articles

Should I sell my Scottish Mortgage shares in 2026?

After a strong run for Scottish Mortgage shares, our writer wonders if he should offload them to bank profits in…

Read more »

Woman riding her old fashioned bicycle along the Beach Esplanade at Aberdeen, Scotland.
Investing Articles

Down 35%! These 2 blue-chips are 2025’s big losers. But are they the best shares to buy in 2026?

Harvey Jones reckons he's found two of the best shares to buy for the year ahead, but he also acknowledges…

Read more »

A senior man and his wife holding hands walking up a hill on a footpath looking away from the camera at the view. The fishing village of Polperro is behind them.
Investing Articles

State Pension worries? 3 investment trusts to target a £2.6m retirement fund

Royston Wild isn't worried about possible State Pension changes. Here he identifies three investment trusts to target a multi-million-pound portfolio.

Read more »

Smiling white woman holding iPhone with Airpods in ear
Dividend Shares

4 dirt-cheap dividend stocks to consider for 2026!

Discover four great dividend stocks that could deliver long-term passive income -- and why our writer Royston Wild thinks they’re…

Read more »

Young mixed-race woman jumping for joy in a park with confetti falling around her
Investing Articles

These fabulous 5 UK stocks doubled in 2025 – can they do it again next year?

These five UK stocks have more than doubled investors' money as the FTSE 100 surges. Harvey Jones wonders if they…

Read more »