Why AstraZeneca plc shares could be the buy of the decade

AstraZeneca plc’s (LON:AZN) share price could double in five years, says G A Chester.

| More on:

The content of this article was relevant at the time of publishing. Circumstances change continuously and caution should therefore be exercised when relying upon any content contained within this article.

You’re reading a free article with opinions that may differ from The Motley Fool’s Premium Investing Services. Become a Motley Fool member today to get instant access to our top analyst recommendations, in-depth research, investing resources, and more. Learn More.

Investors in AstraZeneca (LSE: AZN) in the early years of the 21st century endured a long period of frustration. The shares peaked at just over 3,500p in 2002 and it took until 2013 for them to break through that level again.

The renewed optimism followed a boardroom shake-up in 2012 when investor unrest over the underperforming share price, falling sales and a dearth of new medicines saw the departure of both the chairman and chief executive.

Sales have remained under pressure due to expiring patents on some of the company’s major products, but the market has warmed increasingly to Astra’s future prospects. The shares are now trading at around 5,000p but I believe they’re set to rise much higher.

Turnaround

When new chief executive Pascal Soriot arrived he found a company that was “imploding” and in need of radical overhaul. Research — the lifeblood of a pharma company — was sprawling, inefficient and lacking in dynamism and new ideas.

Soriot has shrunk its operations to focus on core areas like cancer, respiratory and cardiovascular disease. He’s moved the business closer, both culturally and physically, to cutting-edge academic research. It’s taken time but Astra now has one of the strongest pipelines in the industry.

Trough year

The business hasn’t quite reached the inflection point of a return to growth but it’s fast approaching. It reported in its Q3 results that the impact from the loss of exclusivity on its products is starting to recede and laid out the major news flow on the pipeline it expects through 2018 — an impressive list of regulatory submissions and decisions.

City analysts expect 2018 to be the trough year for earnings. The consensus forecast gives a P/E of 18.3 but this comes down to 16.3 for 2019 on expectations of earnings growth kicking in for the first time. One of Soriot’s achievements for shareholders has been to maintain the company’s dividend throughout the overhaul of the business. As such, buyers of the shares today have a prospective yield of around 4%. However, I believe this could be just the topping on far more substantial capital gains.

Buy of the decade?

Even when earnings were falling and Soriot’s turnaround strategy was in its infancy, Astra was viewed as a valuable franchise by trade players. In 2014, he persuaded shareholders to reject a 5,500p a share offer from US giant Pfizer. He argued that the terms “substantially undervalue AstraZeneca” and pledged to achieve revenues of $45bn by 2023.

He may have made himself a hostage to fortune — the target is ambitious — but if he can deliver anywhere near that kind of revenue, the rewards for investors are likely to be substantial. Astra generated revenue of $23bn in its last financial year, making a net profit of $3.5bn at a margin of a bit over 15%. Roll on to revenue of $45bn at the same margin in 2023 and we’d be looking at a net profit of $6.8bn. Furthermore, an improvement in the margin to nearer 20% (net profit $9bn) wouldn’t be entirely fanciful.

I see the stock as a good buy today, taking a considerably more conservative view of growth prospects, but if the company does achieve its ambitious targets, it could be the buy of the decade, certainly among its big pharma peers.

G A Chester has no position in any of the shares mentioned. The Motley Fool UK has recommended AstraZeneca. Views expressed on the companies mentioned in this article are those of the writer and therefore may differ from the official recommendations we make in our subscription services such as Share Advisor, Hidden Winners and Pro. Here at The Motley Fool we believe that considering a diverse range of insights makes us better investors.

More on Investing Articles

Investing Articles

Is 2026 the year the Diageo share price bounces back?

Will next year be the start of a turnaround for the Diageo share price? Stephen Wright looks at a key…

Read more »

Investing Articles

Here’s my top FTSE 250 pick for 2026

UK investors looking for under-the-radar opportunities should check out the FTSE 250. And 2026 could be an exciting year for…

Read more »

Yellow number one sitting on blue background
Investing Articles

Here’s my number 1 passive income stock for 2026

Stephen Wright thinks a 5.5% dividend yield from a company with a strong competitive advantage is something passive income investors…

Read more »

Thoughtful man using his phone while riding on a train and looking through the window
Investing Articles

Should I sell my Scottish Mortgage shares in 2026?

After a strong run for Scottish Mortgage shares, our writer wonders if he should offload them to bank profits in…

Read more »

Woman riding her old fashioned bicycle along the Beach Esplanade at Aberdeen, Scotland.
Investing Articles

Down 35%! These 2 blue-chips are 2025’s big losers. But are they the best shares to buy in 2026?

Harvey Jones reckons he's found two of the best shares to buy for the year ahead, but he also acknowledges…

Read more »

A senior man and his wife holding hands walking up a hill on a footpath looking away from the camera at the view. The fishing village of Polperro is behind them.
Investing Articles

State Pension worries? 3 investment trusts to target a £2.6m retirement fund

Royston Wild isn't worried about possible State Pension changes. Here he identifies three investment trusts to target a multi-million-pound portfolio.

Read more »

Smiling white woman holding iPhone with Airpods in ear
Dividend Shares

4 dirt-cheap dividend stocks to consider for 2026!

Discover four great dividend stocks that could deliver long-term passive income -- and why our writer Royston Wild thinks they’re…

Read more »

Young mixed-race woman jumping for joy in a park with confetti falling around her
Investing Articles

These fabulous 5 UK stocks doubled in 2025 – can they do it again next year?

These five UK stocks have more than doubled investors' money as the FTSE 100 surges. Harvey Jones wonders if they…

Read more »