Better buy: GlaxoSmithKline plc vs Shire plc

Growth and income investors will both find something to cheer with GlaxoSmithKline plc (LON: GSK) and Shire plc (LON: SHP).

The content of this article was relevant at the time of publishing. Circumstances change continuously and caution should therefore be exercised when relying upon any content contained within this article.

You’re reading a free article with opinions that may differ from The Motley Fool’s Premium Investing Services. Become a Motley Fool member today to get instant access to our top analyst recommendations, in-depth research, investing resources, and more. Learn More.

On the face of it, GlaxoSmithKline (LSE: GSK) and Shire (LSE: SHP) are both very similar; large, globe-spanning pharmaceutical companies with cutting-edge treatments for a range of diseases. But in fact the two companies are taking very, very different paths towards future growth, which makes it incredibly important for investors to understand the differences before committing to an investment in either.

Shire, after a $50bn three-year acquisition spree, is now positioned as one of the world’s foremost makers of treatments for rare diseases, which are classified as those that affect fewer than one in 2,000 people. CEO Flemming Ornskov has staked out this position in the belief that creating treatments for rare diseases will involve less competition from other pharma giants and bring higher pricing power for Shire.

On the other hand, outgoing GSK CEO Andrew Witty has forged ahead with an ambitious plan to de-risk the company’s operations by building up a large and relatively stable consumer health business. After an asset swap with Novartis in 2015, a full 45% of GSK’s revenue comes from selling vaccines and consumer products such as Sensodyne toothpaste and Theraflu cold and flu treatment.

So, we see the diverging paths Shire and GSK are taking, but which will reward investors the most in the coming decades?

Growth from here to infinity and beyond?

Growth investors will likely find Shire the winner as management is targeting $20bn in annual revenue by 2020. After $36bn worth of acquisitions in 2016 alone making comparisons to past revenue is a bit tricky but if we take the $3.45bn of Q3 revenue and annualise that, it comes out to around $14bn in yearly sales. This is obviously an ambitious task, but Shire is already seeing results as legacy product sales increased 13% year-on-year in Q3 and new acquisitions also exhibited strong positive momentum.

This isn’t to say GSK lacks growth potential, because the company did report an 8% year-on-year rise in Q3 sales, even excluding the positive effects of the weak pound. Growth is being driven by a 20% rise in vaccine sales and stunning 79% increase in sales of a series of new drugs just now entering the market. But, even if this level of growth were to continue it would lag behind Shire’s growth targets, which makes the ambitious rare disease seller the winner of this portion of the contest.

A dividend investor’s dream

Income investors will undoubtedly find GSK their favourite, though. GSK’s shares currently offer a 5.45% yield, miles ahead of Shire’s 0.41% return. GSK is targeting relatively stable dividend payouts of around 80p per share for the next two years, but there’s good long-term growth potential as new drugs enter the market and dividend cover is restored to historical levels. Shire is unlikely to increase dividends significantly in the next few years as the company will be focused on whittling down the $23bn of net debt taken on to fund recent acquisitions.

So far it seems very clear that growth investors will prefer Shire, while more conservative investors will lean towards GSK’s stellar income. However, potential Shire investors always need to keep in the back of their mind the increasing political pressure on drug companies’ pricing structures. Were politicians in the US to crack down on astronomical drug prices, Shire’s business plan would face considerable headwinds.

Is GSK a great option for your retirement portfolio?

Ian Pierce has no position in any shares mentioned. The Motley Fool UK owns shares of and has recommended GlaxoSmithKline. We Fools don't all hold the same opinions, but we all believe that considering a diverse range of insights makes us better investors.

More on Investing Articles

Calendar showing the date of 5th April on desk in a house
Investing Articles

Just 1 year’s Stocks and Shares ISA allowance could generate a £1,900 annual passive income. Here’s how!

Fretting about the upcoming Stocks and Shares ISA contribution deadline? Our writer has an upbeat approach, focusing on ongoing passive…

Read more »

Passive and Active: text from letters of the wooden alphabet on a green chalk board
Investing Articles

As global markets dip, British passive income stocks offer higher yields at cheaper prices

Mark Hartley takes a look at some higher-yielding FTSE stocks that have taken a hard hit in the past month.…

Read more »

Mindful young woman breathing out with closed eyes, calming down in stressful situation, working on computer in modern kitchen.
Investing Articles

2 ‘overpriced’ FTSE 100 shares I’ve got my eye on if the stock market crashes

Never one to miss an opportunity, our writer is putting cash aside to buy quality FTSE 100 stocks in the…

Read more »

Young mixed-race woman looking out of the window with a look of consternation on her face
Investing Articles

With stock market risks emerging, is now the time to consider the 60/40 portfolio?

The stock market could be in for a period of turbulence. Here’s a simple strategy that can help long-term investors…

Read more »

Bus waiting in front of the London Stock Exchange on a sunny day.
Investing Articles

Is a stock market crash coming? It’s not too late to get ready!

Christopher Ruane sees reasons to fear a coming stock market crash. Rather than tying to time it, he's hoping to…

Read more »

Investing Articles

Down 4% in 2026, is now the time to consider buying Nvidia shares

Has Nvidia become too big to keep growing? Or is the stock’s decline this year a chance to think about…

Read more »

Investing Articles

Is the party finally over for Rolls-Royce shares?

Rolls-Royce shares have made investors rich but momentum is slowing and the Iran conflict isn't helping. How worried should we…

Read more »

Asian man looking concerned while studying paperwork at his desk in an office
Investing Articles

7.8% dividend yield! A dirt-cheap UK income share to buy today?

I’m on the hunt for lucrative passive income opportunities, and this under-the-radar FTSE stock currently offers a whopping 7.8% dividend…

Read more »