Share your opinion and earn yourself a free Motley Fool premium report!

We are looking for Fools to join a 75 minute online independent market research forum on 15th / 16th December.

To find out more and express your interest please click here

Up 7.5% in a week! Is the GSK share price about to do an AstraZeneca?

Harvey Jones says the GSK share price has dramatically underperformed FTSE 100 rival AstraZeneca, which has had a stellar run. Now it’s ready to play catch-up.

| More on:

The content of this article was relevant at the time of publishing. Circumstances change continuously and caution should therefore be exercised when relying upon any content contained within this article.

UK financial background: share prices and stock graph overlaid on an image of the Union Jack

Image source: Getty Images

You’re reading a free article with opinions that may differ from The Motley Fool’s Premium Investing Services. Become a Motley Fool member today to get instant access to our top analyst recommendations, in-depth research, investing resources, and more. Learn More.

When I first started writing for The Motley Fool more than two decades ago, the GSK (LSE: GSK) share price was a FTSE 100 shining light.

In my recollection, GlaxoSmithKline, as it was known then, even outshone pharmaceutical sector rival AstraZeneca (LSE: AZN). It’s a different story today.

A tale of two pharma stocks

Since taking the helm in October 2012, CEO Pascal Soriot has transformed AstraZeneca into the UK’s biggest company. Last summer, its market-cap topped £200bn. Although today it’s down to £166bn.

Since the start of the Millennium in January 2000, AstraZeneca’s share price has soared from 2,395p to 10,775p, an impressive increase of around 350%. And that’s before accounting for dividends.

By contrast, GSK’s journey has been more turbulent. From a high of 1,767p in January 2000, its share price has dipped to 1,482p today. While dividends have cushioned the blow, it’s a stark comparison to AstraZeneca’s meteoric rise.​

GSK’s dividend, once seen as a stellar source of income with a typical yield of between 5% and 6%, isn’t what it was. It was frozen at 80p from 2014 to 2021, as CEO Emma Walmsley diverted shareholder cash into R&D, in a bid to replenish the group’s ailing drugs pipeline.

Dividends have slipped

It was then reduced to 57.75p in 2022 following the Haleon spin-off. In 2024, it edged up to 61p, offering a yield of 4.1%.​

Now there’s a glimmer of hope. GSK’s recent Q1 2025 results, published on 30 April, reignited investor interest, pushing the share price up by 7.5% over the past week. Although it’s still down 11% over 12 months.

The company reported sales of £7.52bn, a 4% increase year-on-year. Specialty Medicines were the standout, with sales up 17%, including a 28% rise in Respiratory, Immunology, and Inflammation, and a 53% surge in Oncology. 

Operating profit jumped 50%, while cash generated from operations exceeded £1bn, with free cash flow of £700m.

GSK expects to pay a full-year dividend of 64p per share, up almost 5%, and announced a £2bn share buyback, with £273m repurchased in Q1. 

The company also reaffirmed its full-year guidance, anticipating 3-5% turnover growth and a 6-8% rise in core EPS.

Different stocks, different values

AstraZeneca’s Q1 results, released a day earlier, showed a 10% increase in total revenue to $13.6bn and a 21% rise in core EPS to $2.49. Market reaction was muted, perhaps due to the high expectations set by its recent performance. The AstraZeneca share price is up 3.5% in a week, but like GSK, is down 11% over 12 months.

I don’t hold AstraZeneca shares. Last year, I deemed them too pricey. Instead, I placed my bets on GSK, viewing it as an undervalued opportunity

So far, that decision has left me about 20% down, not helped by concerns over potential US tariffs on pharmaceutical imports. Walmsley believes the company can navigate these challenges through AI integration and supply chain adjustments. We’ll see.

As a contrarian investor, I’m inclined to stick with GSK. There’s potentially more value here, with a price-to-earnings ratio of just over eight, less than half AstraZeneca’s P/E of 17. The recent uptick is encouraging, but there’s still a long road ahead. I’m hoping Walmsley’s masterplan will start paying off, but despite the recent jump, I suspect there’s a long way to go. 

Harvey Jones has positions in GSK. The Motley Fool UK has recommended AstraZeneca Plc and GSK. Views expressed on the companies mentioned in this article are those of the writer and therefore may differ from the official recommendations we make in our subscription services such as Share Advisor, Hidden Winners and Pro. Here at The Motley Fool we believe that considering a diverse range of insights makes us better investors.

More on Investing Articles

Rolls-Royce's Pearl 10X engine series
Investing Articles

Can the Rolls-Royce share price do it again in 2026?

Can the Rolls-Royce share price do it again? The FTSE 100 company has been a star performer in recent years…

Read more »

Businessman hand flipping wooden block cube from 2024 to 2025 on coins
Investing Articles

After huge gains for S&P 500 tech stocks in 2025, here are 4 moves I’m making to protect my ISA and SIPP

Gains from S&P tech stocks have boosted Edward Sheldon’s retirement accounts this year. Here’s what he’s doing now to reduce…

Read more »

View of Lake District. English countryside with fields in the foreground and a lake and hills behind.
Investing Articles

With a 3.2% yield, has the FTSE 100 become a wasteland for passive income investors?

With dividend yields where they are at the moment, should passive income investors take a look at the bond market…

Read more »

Smart young brown businesswoman working from home on a laptop
Investing Articles

Should I add this dynamic FTSE 250 newcomer to my Stocks and Shares ISA?

At first sight, a UK bank that’s joining the FTSE 250 isn’t anything to get excited by. But beneath the…

Read more »

Investing Articles

£10,000 invested in BT shares 3 months ago is now worth

BT shares have been volatile lately and Harvey Jones is wondering whether now is a good time to buy the…

Read more »

Person holding magnifying glass over important document, reading the small print
Investing Articles

After a 66% fall, this under-the-radar growth stock looks like brilliant value to me

Undervalued growth stocks can be outstanding investments. And Stephen Wright thinks he has one in a company analysts seem to…

Read more »

Content white businesswoman being congratulated by colleagues at her retirement party
Investing Articles

Don’t ‘save’ for retirement! Invest in dirt cheap UK shares to aim for a better lifestyle

Investing in high-quality and undervalued UK shares could deliver far better results when building wealth for retirement. Here's how.

Read more »

Black woman using smartphone at home, watching stock charts.
Investing Articles

1 growth and 1 income stock to kickstart a passive income stream

Diversification is key to achieving sustainable passive income. Mark Hartley details two broadly different stocks for beginners.

Read more »