1 heavyweight FTSE 100 share I’d buy as London retakes its crown

Some Footsie firms are extremely large, but that doesn’t mean they couldn’t get even bigger. Here’s one such FTSE 100 share I’d buy right now.

| More on:

The content of this article was relevant at the time of publishing. Circumstances change continuously and caution should therefore be exercised when relying upon any content contained within this article.

British flag, Big Ben, Houses of Parliament and British flag composition

Image source: Getty Images

You’re reading a free article with opinions that may differ from The Motley Fool’s Premium Investing Services. Become a Motley Fool member today to get instant access to our top analyst recommendations, in-depth research, investing resources, and more. Learn More.

After surging to record highs in May, FTSE 100 shares have since come off the boil a bit. But not as much as those in France, where the CAC All-Share index has fallen by around 7.4% in one month.

The index has been driven lower by uncertainty about the outcome of the nation’s looming parliamentary elections. And it means that London retook its title as Europe’s largest stock market from Paris on 17 June.

That said, a quick rebound in giant luxury stocks like Hermes International and LVMH across the Channel could quickly reverse that. It’s neck and neck.

Still, it’s encouraging to see UK blue-chip stocks getting some love recently. Valuations are attractive and dividends are high, which has been attracting overseas investors.

Here is one Footsie stock that I’d buy today, despite its enormous size.

Still growing strongly

I’m talking about AstraZeneca (LSE: AZN), which is London’s largest firm with a market cap of £192bn.

The first thing I like here is that demand for AstraZeneca’s products, which includes treatments for cardiovascular diseases and various types of cancer, is generally stable across the economic cycle.

However, the pharmaceutical giant is doing much better than stable. In 2023, its revenue rose 6% year on year to $45,8bn, despite a huge decline from its Covid medicines (it has now withdrawn its Covid vaccine due to low demand).

Excluding these, total revenue actually jumped 15% and product sales increased 14%. And core earnings per share (EPS) advanced 15% to $7.26.

CEO Pascal Soriot said: “We expect another year of strong growth in 2024, driven by continued adoption of our medicines across geographies. Our differentiated and growing portfolio of approved medicines, global reach and rich R&D pipeline give us confidence that we will continue to deliver industry-leading growth.”

Looking ahead, the oncology market is sadly set to grow due to rising cases of cancer globally. But AstraZeneca is a world-leader here. Its blockbuster cancer drug, Tagrisso, has proven to reduce the risk of the disease spreading by an incredible 84% in patients with a type of Stage 3 lung cancer.

Risks to consider

After rising 16% year to date, the stock isn’t exactly cheap at 19.2 times forward earnings. That’s far less than Footsie peer GSK, which is trading at just 10.1 times forecast earnings for 2024.

However, I think this disparity simply reflects the much faster growth of AstraZeneca, its far deeper pipeline of drugs, and GSK’s ongoing litigation issues. A judge in the US has just allowed over 70,000 lawsuits alleging GSK’s discontinued heartburn drug, Zantac, caused cancer.

Of course, that doesn’t mean AstraZeneca couldn’t one day face similar problems. Litigation is a key risk in the pharma industry, as is adverse regulation, patent expirations, and clinical trial failures.

I’d still invest today

Longer term though, I’m very bullish on the sector and AstraZeneca in particular.

This is due to the powerful trend of a rapidly ageing global population, especially in China where the company has a growing presence. This could boost demand for its medicines for decades.

And with the firm aiming to grow revenue by 75% to $80bn by 2030, I think the shares will continue to handily outperform the FTSE 100. That’s why I treated myself to a few not long back.

Ben McPoland has positions in AstraZeneca Plc. The Motley Fool UK has recommended AstraZeneca Plc and GSK. Views expressed on the companies mentioned in this article are those of the writer and therefore may differ from the official recommendations we make in our subscription services such as Share Advisor, Hidden Winners and Pro. Here at The Motley Fool we believe that considering a diverse range of insights makes us better investors.

More on Investing Articles

Yellow number one sitting on blue background
Investing Articles

I asked ChatGPT to pick 1 growth stock to put 100% of my money into, and it chose…

Betting everything on a single growth stock carries massive danger, but in this thought experiment, ChatGPT endorsed a FTSE 250…

Read more »

Portrait of pensive bearded senior looking on screen of laptop sitting at table with coffee cup.
Investing Articles

How little is £1,000 invested in Diageo shares at the start of 2025 worth now?

Paul Summers takes a closer look at just how bad 2025 has been for holders of Diageo's shares. Will things…

Read more »

Aston Martin DBX - rear pic of trunk
Investing Articles

After a terrible 2025, can the Aston Martin share price bounce back?

The Aston Martin share price has shed 41% of its value in 2025. Could the coming year offer any glimmer…

Read more »

Close-up of British bank notes
Investing Articles

How much do you need in an ISA to target £3,000 per month in passive income?

Ever thought of using an ISA to try and build monthly passive income streams in four figures? Christopher Ruane explains…

Read more »

piggy bank, searching with binoculars
Investing Articles

Want to aim for a million with a spare £500 per month? Here’s how!

Have you ever wondered whether it is possible for a stock market novice to aim for a million? Our writer…

Read more »

Investing Articles

Want to start buying shares next week with £200 or £300? Here’s how!

Ever thought of becoming a stock market investor? Christopher Ruane explains how someone could start buying shares even on a…

Read more »

Rear view image depicting a senior man in his 70s sitting on a bench leading down to the iconic Seven Sisters cliffs on the coastline of East Sussex, UK. The man is wearing casual clothing - blue denim jeans, a red checked shirt, navy blue gilet. The man is having a rest from hiking and his hiking pole is leaning up against the bench.
Investing Articles

2 ideas for a SIPP or ISA in 2026

Looking for stocks for an ISA or SIPP portfolio? Our writer thinks a FTSE 100 defence giant and fallen pharma…

Read more »

Midnight is celebrated along the River Thames in London with a spectacular and colourful firework display.
Investing Articles

Could buying this stock at $13 be like investing in Tesla in 2011?

Tesla stock went on to make early investors a literal fortune. Our writer sees some interesting similarities with this eVTOL…

Read more »