After its £2.4bn demerger, can the GSK share price blossom?

What could becoming a standalone biotech stock mean for the GSK share price? Will it continue to tread water or can it thrive?

The content of this article was relevant at the time of publishing. Circumstances change continuously and caution should therefore be exercised when relying upon any content contained within this article.

You’re reading a free article with opinions that may differ from The Motley Fool’s Premium Investing Services. Become a Motley Fool member today to get instant access to our top analyst recommendations, in-depth research, investing resources, and more. Learn More.

Engineer Project Manager Talks With Scientist working on Computer

Image source: Getty Images

I see interesting times ahead for the GSK (LSE: GSK) share price. GlaxoSmithKline is one of the largest UK biotech stocks trading on the London Stock Exchange. It’s a global giant, with an impressive £1.7bn free cash flow in Q1 alone.

But its share price has been losing ground against its competitors, barely moving over the last five years. It’s not even kept up with inflation.

Could that be about to change as it goes through what it describes as “the most significant corporate change for GSK in the last 20 years”?

Change ahead for the GSK share price?

For some time, the company has been seen to be lagging behind its peers. The last decade has seen it fall from being the third-largest pharmaceutical company in the world down to 14th, based on its market cap.

CEO Emma Walmsley’s response has been the slow progression of plans to split the company in two. And next month should finally see the spin-off of its Consumer Healthcare division into a separate company called Haleon.

But will the estimated £2.4bn cost of the split, one of the most expensive ever, be worth it?

Can GSK benefit from the deal?

The deal will give the company a one-off pocketful of £7bn in cash to spend. That’s seen as fundamental for developing its drugs pipeline, especially in areas such as cancer where it’s noticeably lagging competitors.

This is something that should have a positive impact on its share price. But that’s only if it’s able to transform itself from a global giant into the nimble biotech-focused company it says it wants to be.

In particular, it wants its R&D teams to focus on the science of the immune system, use of human genetics and advanced technologies.

That all sounds wonderful and exciting on paper – but I’m politely curious (read a little sceptical) as to whether reality will match its ambitions. 

Can the ‘new’ GSK compete in the biotech world?

With the pandemic bringing vaccine development sharply into the limelight and increased competition, it’s probably fair to say the biotech world is a tougher place to win these days.

The average business spend for companies developing new drugs may have fallen sharply from a high of $2.8bn to $1.3bn, but that’s still a huge chunk of cash to bet on a single product.

That’s why having a diverse pipeline of drugs is essential for GSK (just like my Foolish investing approach in shares). If one drug fails to perform as hoped, others may plug the revenue gap.

Right now, its focus appears to be on buying its way out of its pipeline problem, such as its recent £1.5bn purchase of Sierra Oncology. Or there’s the £2.1bn upfront payment to Affinivax, a clinical stage vaccine developer.

That’s an expensive approach and not one I’d be keen on seeing it adopt as its main strategy.

The market may well want to see tangible proof of its R&D investments paying off before it rewards GSK with a higher share price.

So to answer my question in the title, I don’t think the fact of the demerger alone will drive the price higher. For now, I’ll hold off on buying GSK shares. But I’ll watch with interest to see if it takes advantage of its post-demerger opportunities.

Michelle Freeman holds shares in GlaxoSmthKline. The Motley Fool UK has recommended GlaxoSmithKline. Views expressed on the companies mentioned in this article are those of the writer and therefore may differ from the official recommendations we make in our subscription services such as Share Advisor, Hidden Winners and Pro. Here at The Motley Fool we believe that considering a diverse range of insights makes us better investors.

More on Investing Articles

Two elderly people relaxing in the summer sunshine Box Hill near Dorking Surrey England
Investing Articles

Forget the FTSE 100 and come back after summer? Here’s my plan!

With the FTSE 100 moving around in a volatile way, should our writer just forget all about it for a…

Read more »

Young female hand showing five fingers.
Investing Articles

£20,000 invested in a Stocks and Shares ISA 5 years ago could now be worth…

The last five years have been something of a roller coaster for the markets. How would £20k in a Stocks…

Read more »

Man hanging in the balance over a log at seaside in Scotland
Investing Articles

Stock market correction: a once-in-a-decade chance to build big passive income?

Ben McPoland takes a closer look at a high-yield passive income stock from the FTSE 250 that investors have been…

Read more »

Portrait of elderly man wearing white denim shirt and glasses looking up with hand on chin. Thoughtful senior entrepreneur, studio shot against grey background.
Investing Articles

In volatile markets, could National Grid dividends be a safe haven?

National Grid offers a dividend yield well above the FTSE 100 and aims to keep growing its payout per share.…

Read more »

Finger clicking a button marked 'Buy' on a keyboard
Investing Articles

Down 25%, are Barclays shares simply too cheap to ignore?

Barclays shares have given up a chunk of their recent gains since the Middle East powder keg ignited. Should investors…

Read more »

Woman riding her old fashioned bicycle along the Beach Esplanade at Aberdeen, Scotland.
Investing Articles

How much would someone need in an ISA to target a £1,000 monthly second income?

Christopher Ruane explains how someone could use an empty Stocks and Shares ISA to target a four-figure monthly second income…

Read more »

Investor looking at stock graph on a tablet with their finger hovering over the Buy button
Investing Articles

Are investors taking a big gamble chasing Rolls-Royce shares higher and higher?

With Rolls-Royce shares having fallen back from their peak, the temptation to see this as a buying opportunity must be…

Read more »

Cargo containers with European Union and British flags reflecting Brexit and restrictions in export and import
Investing Articles

Down 70%, is Fevertree Drinks a share to consider buying at 815p?

Fevertree reported its 2025 earnings today and the investors liked what they saw. So is this a share to consider…

Read more »