This FTSE 100 stock would’ve tripled my money in 10 years. Can it happen again?

Manika Premsingh holds this FTSE 100 stock in her portfolio already, but is now wondering if it is likely to continue rising like it has in the past. 

| More on:

The content of this article was relevant at the time of publishing. Circumstances change continuously and caution should therefore be exercised when relying upon any content contained within this article.

You’re reading a free article with opinions that may differ from The Motley Fool’s Premium Investing Services. Become a Motley Fool member today to get instant access to our top analyst recommendations, in-depth research, investing resources, and more. Learn More.

Plenty of high performing stocks are part of the FTSE 100 index. But not every stock is made equal. Some are definitely better buys than others and have managed to reward investors again and again. Like the the healthcare star AstraZeneca (LSE: AZN). If I had bought it 10 years ago, it would have tripled my money by now. 

AstraZeneca’s eye-watering valuation

I know that on the face of it, it comes with risks. A big one is its market valuation. I spend a fair bit of time researching cheap stocks, because they might just have the potential to rise significantly more than pricey ones. And by that argument, AstraZeneca should be an absolute no-go. Right now, it has an unbelievable price-to-earnings (P/E) ratio of 1,510 times as per my calculations based on its recently released full-year earnings report. The only other stock I have seen with such high valuations is Tesla, and there is no way I am about to buy it. 

Scratching the surface

If I dig deeper into this story, however, it turns out that AstraZeneca’s full-year 2021 P/E has risen to crazy levels only because of a massive fall in its reported earnings, which needs to be taken with a healthy measure of salt in my view. That is because the latest drop is driven partly by the company’s acquisition of US-based rare diseases’ focused company Alexion, a move whose potential impact I had wondered about earlier as well. It is also down because of items like restructuring, amortisation, and impairments. 

If I instead consider the core earnings measure, the number that removes the noise and focuses on the earnings from the main business, it is much healthier. And it gives me a P/E of 22 times, which I think is a truer reflection of the company’s valuation. The reported number is too much of an outlier in my view to give any real perspective!

What is really going on with this FTSE 100 stock?

At this valuation, AstraZeneca does not look terrible expensive to me. I mean it is not significantly higher than that for the FTSE 100 at 16 times. And this is a healthy defensive, with a good outlook for the current year. Speaking of its outlook, the company is optimistic despite the fact that its Covid-19 related numbers are expected to weaken as the pandemic’s grip wanes. Its crucial cancer treatments are likely to hold it in good stead over the foreseeable future. And it helps that it is adding to its portfolio of products, like through the acquisition of Alexion. 

I first bought the stock a few years ago, and occasionally buy it on dips even now. It has not disappointed me so far, I look forward to buying more of it in the near future. And holding it for a long time. Because I think it could triple my money over the next decade as well. 

Manika Premsingh owns AstraZeneca. The Motley Fool UK has no position in any of the shares mentioned. Views expressed on the companies mentioned in this article are those of the writer and therefore may differ from the official recommendations we make in our subscription services such as Share Advisor, Hidden Winners and Pro. Here at The Motley Fool we believe that considering a diverse range of insights makes us better investors.

More on Investing Articles

Female student sitting at the steps and using laptop
Investing Articles

Getting started with investing? Here are 3 UK stocks to take a look at

The next time the stock market opens, it will be the new financial year. And Stephen Wright has three UK…

Read more »

Diverse children studying outdoors
Growth Shares

2 growth shares beating Rolls-Royce stock so far this year

Jon Smith points out some growth shares that have come out of the blocks strongly in 2026, with momentum right…

Read more »

Calendar showing the date of 5th April on desk in a house
Investing Articles

How much would someone need in an ISA to double the state pension and target a £24,436 annual income?

A full state pension is £230.25 per week. But James Beard reckons it’s possible to aim to double this by…

Read more »

Smartly dressed middle-aged black gentleman working at his desk
Investing Articles

New to investing? Here’s how to use the stock market to try and generate a second income

Is investing in the stock market a better way of earning a second income than starting a business? Stephen Wright…

Read more »

UK supporters with flag
Investing Articles

How much would someone need in a Stocks and Shares ISA to target a £1,667 monthly second income?

Our writer reckons a Stocks and Shares ISA is a great way of targeting a healthy second income. And it…

Read more »

Hand of person putting wood cube block with word VALUE on wooden table
Investing Articles

April stocks: 2 value shares I’m taking a closer look at

Value investors looking for shares to buy in April have a lot of eye-catching opportunities. Here are two that I…

Read more »

Investing Articles

15 FTSE 100 stocks have fallen 15% or more this year. Here’s my favourite

Our writer is bullish on a few FTSE 100 stocks that have sold off in 2026. But which one has…

Read more »

Shot of an young mixed-race woman using her cellphone while out cycling through the city
Investing Articles

With a P/E of 8.2 and a P/B of 0.7, are Barclays shares cheap?

Barclays' shares look cheap on paper. But is this really the case? James Beard explores both sides of the debate…

Read more »