Forget the Cash ISA! I’d buy this FTSE 100 dividend stock to retire on

With its healthy cash flows and defensive market position, this FTSE 100 stock is worth owning in your retirement portfolio, says Rupert Hargreaves.

The content of this article was relevant at the time of publishing. Circumstances change continuously and caution should therefore be exercised when relying upon any content contained within this article.

You’re reading a free article with opinions that may differ from The Motley Fool’s Premium Investing Services. Become a Motley Fool member today to get instant access to our top analyst recommendations, in-depth research, investing resources, and more. Learn More.

Warren Buffett, who is widely considered to be the best investor in the world, says that he will only buy stocks when he is sure that the underlying business can continue to produce returns for investors for many years to come.

This means he tends to stick with businesses that have robust competitive advantages or defensive characteristics. 

I think GlaxoSmithKline (LSE: GSK) meets this test. As one of the world’s largest pharmaceutical companies, demand for the group’s products should only increase going forward as the world’s population continues to grow and more money is devoted to healthcare. 

Research and development

Glaxo has spent billions over the past few years reinforcing its position in the market. Moreover, under the stewardship of its relatively new CEO Emma Walmsley, the company has refurbished its research and development efforts.

Rather than spending money on a range of different projects with uncertain outcomes, Glaxo is concentrating its R&D efforts on a few key areas such as vaccines, where it has an established reputation as a reliable supplier. 

These actions to streamline the group’s R&D process, are already having an impact on the bottom line.

Overall sales in the third quarter rose 11% to £9.4bn, beating consensus expectations of about £9bn. Vaccines turnover grew 15% to £2.3bn, primarily driven by growth in sales of Glaxo’s shingles treatment, Shingrix, sales of which jumped 76% in the quarter. 

The company is also on track to start selling a new drug, Dostarlimab in the next few months. Designed to treat advanced or recurrent endometrial cancer, Dostarlimab was one of three drugs Glaxo outlined as being pivotal to its future growth at the beginning of 2019.

The other two were Zejula and Belantamab. They’re both oncology treatments acquired when Glaxo bought Tesaro last year. 

The launch of new respiratory medicines Nucala and Trelegy are also helping drive sales growth at Glaxo’s respiratory business. 

Retirement investment

Glaxo’s performance this year outlines why I think this stock should feature in your retirement portfolio. 

As long as the company continues to invest in its treatment pipeline, new products should continue to power sales growth for many decades to come.

And even if the company only grows in line with the rest of the global healthcare industry, I think the stock has the potential to return around 10% per annum for the next decade or so. 

Indeed, according to research from Deloitte, global healthcare spending is set to increase by around 5% per annum to the middle of the next decade. 

If the company’s earnings grow in line with this projection, I think the stock could return around 9.6% per annum when you add in the 4.6% dividend yield to earnings growth. 

This kind of growth is worth paying a premium for, so I think Glaxo’s current P/E of 14.4 isn’t too demanding and could move higher if the company continues to beat City growth expectations. 

Rupert Hargreaves owns no share mentioned. The Motley Fool UK owns shares of and has recommended GlaxoSmithKline. Views expressed on the companies mentioned in this article are those of the writer and therefore may differ from the official recommendations we make in our subscription services such as Share Advisor, Hidden Winners and Pro. Here at The Motley Fool we believe that considering a diverse range of insights makes us better investors.

More on Investing Articles

Investing Articles

Will the S&P 500 crash in 2026?

The S&P 500 delivered impressive gains in 2025, but valuations are now running high. Are US stocks stretched to breaking…

Read more »

Teenage boy is walking back from the shop with his grandparent. He is carrying the shopping bag and they are linking arms.
Investing Articles

How much do you need in a SIPP to generate a brilliant second income of £2,000 a month?

Harvey Jones crunches the numbers to show how investors can generate a high and rising passive income from a portfolio…

Read more »

Investing Articles

Will Lloyds shares rise 76% again in 2026?

What needs to go right for Lloyds shares to post another 76% rise? Our Foolish author dives into what might…

Read more »

Investing Articles

How much passive income will I get from investing £10,000 in an ISA for 10 years?

Harvey Jones shows how he plans to boost the amount of passive income he gets when he retires, from FTSE…

Read more »

Investing Articles

Down 34% in 2025 — but could this be one of the UK’s top growth stocks for 2026?

With clarity over research funding on the horizon, could Judges Scientific be one of the UK’s best growth stocks to…

Read more »

piggy bank, searching with binoculars
Investing Articles

Can the rampant Barclays share price beat Lloyds in 2026?

Harvey Jones says the Barclays share price was neck and neck with Lloyds over the last year, and checks out…

Read more »

Investing Articles

Here’s how Rolls-Royce shares could hit £25 in 2026

If Rolls-Royce shares continue their recent performance, then £25 might be on the cards for 2026. Let's take a look…

Read more »

Departure & Arrival sign, representing selling and buying in a portfolio
Investing Articles

Prediction: in 2026 the red-hot Rolls-Royce share price could turn £10,000 into…

Harvey Jones can't believe how rapidlly the Rolls-Royce share price has climbed. Now he looks at the FTSE 100 growth…

Read more »