GlaxoSmithKline plc vs Smith & Nephew plc: which is the FTSE 100’s best medical marvel?

Royston Wild considers whether investors should pile into FTSE 100 (INDEXFTSE: UKX) giants GlaxoSmithKline plc (LON: GSK) or Smith & Nephew plc (LON: SN).

| More on:

The content of this article was relevant at the time of publishing. Circumstances change continuously and caution should therefore be exercised when relying upon any content contained within this article.

You’re reading a free article with opinions that may differ from The Motley Fool’s Premium Investing Services. Become a Motley Fool member today to get instant access to our top analyst recommendations, in-depth research, investing resources, and more. Learn More.

Today I’m weighing up whether GlaxoSmithKline (LSE: GSK) or Smith & Nephew (LSE: SN) is the better FTSE 100 (INDEXFTSE: UKX) medical pick for savvy stock pickers.

Testing times

Make no mistake: the business of drugs development is a hugely-risky affair, where testing setbacks can lead to lost millions in the case of product delays and cancellations, not to mention a hefty rise in R&D costs.

And for ‘Big Pharma’ plays like GlaxoSmithKline this is a particular problem. The Brentford firm has seen earnings steadily sink during the past five years as key labels have lost patent protection. So bringing on-stream the next generation of sales drivers is critical to get earnings firing again.

GlaxoSmithKline has plans to submit 40 products for regulatory submission during the next decade, around 80% of which the firm believes can lead the industry in their respective fields. However, the scrapping of its IONIS-TTR cardiovascular treatment on safety grounds last month illustrates the hit and miss nature of pharmaceuticals production.

Joints joy

Limbs-and-joints manufacturer Smith & Nephew doesn’t face the same level of unpredictability when it comes to product development, of course. But that’s not to say the bio engineer doesn’t face revenues issues of its own.

Indeed, Smith & Nephew saw sales in emerging markets slump 6% during January-March as uptake from China and the Middle East dived. And prolonged weakness in these critical growth regions could significantly hamper the medical giant’s long-term growth story.

But I believe there’s still plenty to get excited about. Smith & Nephew’s robust position in fast-growing segments like sports medicine continues to generate splendid returns, while acquisition activity is also bolstering the firm’s position in other key areas.

So what does the City think?

The number crunchers certainly believe that Smith & Nephew is in good enough shape to keep earnings growing, and rises of 1% and 12% are pencilled-in for 2016 and 2017, respectively. These produce decent-if-unspectacular P/E ratings of 18.8 times and 17 times.

By comparison, GlaxoSmithKline boasts P/E ratings of 15.6 times and 15.1 times for these periods as earnings are expected to spark again — growth of 16% and 5% is expected this year as analysts put faith in the drugs developer’s product pipeline.

Sure, GlaxoSmithKline may carry a higher risk profile than Smith & Nephew. But I believe both firms have the know-how to deliver splendid earnings growth in the years ahead, particularly as global healthcare investment keeps on surging.

Having said that, dividend chasers may find themselves drawn in by GlaxoSmithKline’s gigantic yields — the City expects the pharma play to make good on planned dividends of 80p per share for this year and next, creating a monster 5.7% yield.

In contrast, Smith & Nephew carries yields of only 2% and 2.2% for these periods thanks to predicted rewards of 21.9p and 24.4p per share.

Royston Wild has no position in any shares mentioned. The Motley Fool UK owns shares of and has recommended GlaxoSmithKline. We Fools don't all hold the same opinions, but we all believe that considering a diverse range of insights makes us better investors.

More on Investing Articles

DIVIDEND YIELD text written on a notebook with chart
Investing Articles

Down 15% and a yield of 7.9%! Is this REIT dividend champion now irresistible?

This real estate investment trust (REIT) has one of the highest dividend yields on the London Stock Market. Royston Wild…

Read more »

Mature black woman at home texting on her cell phone while sitting on the couch
Investing Articles

Down 32% and with a P/E of 9.5, is this FTSE 250 share too cheap to ignore?

This FTSE 250 share is in freefall after slashing guidance for this financial year. But Royston Wild eyes a potential…

Read more »

Chalkboard representation of risk versus reward on a pair of scales
Growth Shares

Why high oil prices could be good news for Lloyds shares

Jon Smith talks through the implications of elevated oil prices and translates that through to the potential impact on Lloyds'…

Read more »

Investing Articles

Lists of income stocks to buy almost never include this one — but with a forecast 8.2% yield, I think they should!

This FTSE firm, not always seen as an income play, has a forecast yield of 8.2%, underlining why it's one…

Read more »

Person holding magnifying glass over important document, reading the small print
Investing Articles

Aviva’s share price is down 13% to under £7, despite outstanding 2025 results! Time for me to buy more?

I think Aviva’s share price reflects an outdated view of the business, and that gap between perception and reality is…

Read more »

Arrow symbol glowing amid black arrow symbols on black background.
Investing Articles

Shell’s £33+ share price is near an all-time high, so why am I going to buy more as soon as possible?

Shell's strong cash generation and improving growth drivers contrast with a share price well below my valuation, suggesting major long‑term…

Read more »

DIVIDEND YIELD text written on a notebook with chart
Investing Articles

An 8.4% forecast yield but down 16%! Time for me to buy more of this FTSE 100 passive income star?

This FTSE 100 passive‑income machine is delivering rising payouts and strong forecasts, and its share price suggests the market hasn’t…

Read more »

CEO Mark Zuckerberg at F8 2019 event
Investing Articles

£10,000 invested in Meta Platforms Stock 5 years ago is now worth…

Meta Platforms has been throwing good money after bad at Reality Labs since 2021, but the stock has more than…

Read more »