Are Synairgen plc or Immupharma plc better investments than AstraZeneca plc?

Should you invest in juniors Synairgen plc (LON:SNG) and Immupharma plc (LON:IMM) or giant AstraZeneca plc (LON:AZN)?

| More on:

The content of this article was relevant at the time of publishing. Circumstances change continuously and caution should therefore be exercised when relying upon any content contained within this article.

You’re reading a free article with opinions that may differ from The Motley Fool’s Premium Investing Services. Become a Motley Fool member today to get instant access to our top analyst recommendations, in-depth research, investing resources, and more. Learn More.

Junior pharmaceutical stocks have the potential to create huge value for shareholders if successful. These two stocks both have drugs that could create many millions of revenue in the future. Will either outperform pharma giant AstraZeneca (LSE: AZN), though?

Respiratory focus

Synairgen (LSE: SNG) is a drug development company founded by three University of Southampton professors, the business focusing on treating respiratory diseases such as asthma. The company has a potential asthma treatment which is being developed with AstraZeneca after signing a licensing and development deal in 2014. The deal is worth up to $232m plus royalties and the drug entered Phase IIa trials in July 2015. Synairgen hopes to release results on the trials sometime in 2017.

The inhaled treatment developed by Synairgen has the potential to be a blockbuster product. Many believe if the drug is approved then AstraZeneca may take over Synairgen to acquire full ownership of the drug. This isn’t the only project in Synairgen’s pipeline: the company recently signed a research collaboration with Pharmaxis to develop a treatment for a fatal lung disease. Chairman Simon Shaw recently commented that “our collaboration with Pharmaxis has begun to yield positive results and we anticipate a Phase I clinical trial in 2017“. 

Lupus treatment

Immupharma (LSE: IMM) is in the process of developing its Lupuzor drug which is currently in Phase III clinical trials at 43 sites across the US and Europe. The company is aiming to release “top line results” by the end of 2017. The potential of the drug is huge and the company thinks the Lupus market has the potential for multi-billion dollar sales. The company made a £3.9m loss last year mainly due to research and development costs which is perfectly normal for a junior pharma stock. Immupharama recently carried out a £8.4m funding round which should fund the company right through to 2018.  It’s clear to me that Immupharama has the potential to make huge returns for shareholders if Lupuzor is brought to the market. Investors should keep an eye on the company next year when initial trial results are expected. 

Exciting pipeline

AstraZeneca is different to the two juniors as it has a pipeline full of new and exciting drugs going through clinical trials. The company pays a chunky 4.8% dividend and trades on an attractive 14.2 times earnings. AstraZeneca has the firepower to make acquisitions in the future which should boost earnings and keep the company moving forward with new drugs and treatments. The defensive qualities of the stock should mean it holds up well after the EU referendum on the 23rd June, and investors looking to shelter cash should take a serious look at the company. Although AstraZeneca is unlikely to give you the huge gains that are possible with Synairgen and Immupharma, it could be a great core holding for the long term. 

Investing in junior pharma stocks is a risky game. The rewards could be massive, but most drugs never make it to market and companies can lose millions in research and development. 

Jack Dingwall has no position in any shares mentioned. The Motley Fool UK has recommended AstraZeneca. We Fools don't all hold the same opinions, but we all believe that considering a diverse range of insights makes us better investors.

More on Investing Articles

Business manager working at a pub doing the accountancy and some paperwork using a laptop computer
Investing Articles

Are investors taking a massive gamble by chasing the BP share price higher?

Investors who thought the BP share price would continue to rocket as the Iran war intensifies may have been surprised…

Read more »

Young woman working at modern office. Technical price graph and indicator, red and green candlestick chart and stock trading computer screen background.
Investing Articles

Down 23%, consider this FTSE 250 share that’s boosted profit forecasts!

This FTSE 250 tech share's leapt 8% on Wednesday (18 March) after it raised full-year profit forecasts. Is now the…

Read more »

Woman riding her old fashioned bicycle along the Beach Esplanade at Aberdeen, Scotland.
Investing Articles

4 reasons the Rolls-Royce share price might be headed to £24

Could the Rolls-Royce share price double from around £12 to closer to £24? Here are a few reasons why it…

Read more »

Passive income text with pin graph chart on business table
Investing Articles

How much passive income can you earn by investing £20,000 in a Stocks and Shares ISA?

With dividend yields up to 10%, REITs might be some of the top passive income opportunities for UK investors in…

Read more »

Group of friends meet up in a pub
Investing Articles

Diageo shares are back at 2012 levels. Time to consider buying?

Diageo shares have fallen around 65% from their highs and now trade at levels not seen for well over a…

Read more »

Investing Articles

Softcat: a FTSE 250 tech stock offering growth, dividends and value

Right now, the share price of FTSE 250 IT company Softcat is well off its highs. And at current levels,…

Read more »

Black woman using smartphone at home, watching stock charts.
US Stock

3 huge pieces of news that could impact the Nvidia share price

Jon Smith talks through some key reveals and implications for the Nvidia share price from the company conference taking place…

Read more »

Three signposts pointing in different directions, with 'Buy' 'Sell' and 'Hold' on
Investing For Beginners

This FTSE stock is now trading at the lowest level since the 1990s! Should I buy?

Jon Smith explains why a FTSE share is currently at multi-decade lows and might surprise some with his decision on…

Read more »