How Much Lower Can AstraZeneca plc, GlaxoSmithKline plc, Shire PLC And Hikma Pharmaceuticals Plc Go?

Do AstraZeneca plc (LON: AZN), GlaxoSmithKline plc (LON: GSK), Shire PLC (LON: SHP) and Hikma Pharmaceuticals Plc (LON: HIK) have further to fall?

| More on:

The content of this article was relevant at the time of publishing. Circumstances change continuously and caution should therefore be exercised when relying upon any content contained within this article.

You’re reading a free article with opinions that may differ from The Motley Fool’s Premium Investing Services. Become a Motley Fool member today to get instant access to our top analyst recommendations, in-depth research, investing resources, and more. Learn More.

It’s been a rough year so far for pharma stocks. After a record-breaking 2015, when valuations across the industry spiked following a wave of M&A activity, the sector has been on the back foot ever since the beginning of 2016.

Deals gone wrong 

Hikma Pharmaceuticals (LSE: HIK) is the worst performing UK pharma large-cap. Shares in the company have fallen by 17% year-to-date thanks to its botched acquisition of Roxane Laboratories from Boehringer Ingelheim. It emerged last month that Roxane Laboratories’ sales weren’t as high as initially expected and even though the deal had been agreed between the two parties, Hikma declared that it was renegotiating the purchase price.

Last week, alongside its full-year 2015 results, Hikma announced that it was paying $535m less cash for Roxane Laboratories to reflect lower sales. Still, the company’s results for 2015 marginally beat expectations with pre-tax profits falling 12% on revenues down 3.3%. 

Even after recent declines Hikma’s shares trade at a forward P/E of 21.1 and City analysts expect the company’s earnings per share to contract by 14% this year as a result of the Roxane deal. A rich valuation of 21.1 time forward earnings leaves little room for error if the company slips up again.

Similarly, shares in Shire (LSE: SHP) have fallen 16.5% year-to-date on concerns that the company is overpaying to acquire peer Baxalta. However, these declines have left Shire’s shares looking extremely attractive on a valuation basis.

When the deal between Baxalta and Shire completes, the enlarged group will be the world’s largest producer of rare disease treatments. And after recent declines, Shire trades at a forward P/E of 14 for the year ending 31/12/2015 and 12.5 for the year ending 31/12/2016. The shares currently support a dividend yield of 0.5%.

Plenty of uncertainty 

AstraZeneca’s (LSE: AZN) shares have lost 15% of their value so far this year, following the wider pharma sector lower. 

Astra’s future depends on its ability to bring its pipeline of treatments to market. If the company can successfully bring a wave of new products to market to replace the drugs that are losing patent protection this year, then Astra’s future could be bright. But there’s plenty of execution risk here. Astra’s shares currently trade at a forward P/E of 13.9 and yield 5%. With so much uncertainty about Astra’s future, there could be better investments out there.

A year of growth 

Finally, GlaxoSmithKline (LSE: GSK), which is the best performing large listed UK pharma stock. Shares in the company have gained 1.5% excluding dividends so far this year, and there could be further gains to come. 

Management expects Glaxo’s core earnings per share figure to grow by double-digits this year, the first such increase the company has been able to achieve for five years.

If Glaxo can hit this target, then it will have shown investors that it’s on track with its restructuring programme, which should then spark a rally in the company’s shares. Glaxo’s shares currently trade at a forward P/E of 16.2 and support a yield of 5.9%.

Rupert Hargreaves owns shares of GlaxoSmithKline. The Motley Fool UK has recommended AstraZeneca, GlaxoSmithKline, and Hikma Pharmaceuticals. We Fools don't all hold the same opinions, but we all believe that considering a diverse range of insights makes us better investors.

More on Investing Articles

Artillery rocket system aimed to the sky and soldiers at sunset.
Investing Articles

£7,500 invested in BAE Systems shares 10 days ago is now worth…

Why have BAE Systems shares experienced a sudden double-digit pullback? And does this present a buying opportunity for my portfolio?

Read more »

Picture of an easyJet plane taking off.
Investing Articles

£10,000 invested in easyJet shares 4 weeks ago is now worth…

It's been a crazy month for easyJet shares. Here's what would have happened to an investor's £10,000 stake put to…

Read more »

CEO Mark Zuckerberg at F8 2019 event
Investing Articles

Down 31%, is this a rare chance to buy Meta stock for my ISA cheaply?

After rising to near $800 in 2025, Meta stock has pulled back to around $550. Edward Sheldon looks at whether…

Read more »

Santa Clara offices of NVIDIA
Investing Articles

18% off its peak, is Nvidia stock now attractively priced?

Nvidia stock has given up almost a fifth of the price it commanded at its peak over the past year.…

Read more »

Aston Martin DBX - rear pic of trunk
Investing Articles

The Aston Martin share price destruction helps illustrate 5 common investing mistakes!

The Aston Martin share price has been a disaster for investors. Christopher Ruane highlights a handful of lessons we can…

Read more »

DIVIDEND YIELD text written on a notebook with chart
Dividend Shares

How this stock market correction can help boost a second income by 25%

Jon Smith explains how rising dividend yields across some existing income shares can be seen as an opportunity to grow…

Read more »

Middle-aged Caucasian woman deep in thought while looking out of the window
Investing Articles

Considering a SIPP? Today’s market could provide an excellent opportunity to start

Mark Hartley breaks down the benefits of using a SIPP for retirement, and how current market conditions could offer a…

Read more »

Calendar showing the date of 5th April on desk in a house
Investing Articles

Looking for last-minute ISA ideas? Check out these UK stocks before April 3

Easter bank holidays mean the deadline to put cash into a Stocks and Shares ISA might be closer than UK…

Read more »