Which Company Suits Your Portfolio: AstraZeneca plc Or GlaxoSmithKline plc ?

Which is the better pick for your portfolio, AstraZeneca plc (LON:AZN), or GlaxoSmithKline plc (LON: GSK)?

| More on:

The content of this article was relevant at the time of publishing. Circumstances change continuously and caution should therefore be exercised when relying upon any content contained within this article.

You’re reading a free article with opinions that may differ from The Motley Fool’s Premium Investing Services. Become a Motley Fool member today to get instant access to our top analyst recommendations, in-depth research, investing resources, and more. Learn More.

Pharmaceutical companies make great investments due to their defensive nature and reliable dividend payouts. The FTSE 100’s two pharma giants, AstraZeneca (LSE:AZN) (NYSE: AZN.US) and GlaxoSmithKline (LSE: GSK) (NYSE: GSK.US) are no different. But if you could only choose one, which would be the best pick for your portfolio?

Growth seekers

Astra has one thing on its mind at the moment and that’s growth. After fending off a bid from US pharma giant Pfizer, the company laid out an ambitious growth plan to deliver annual revenues of $45bn by 2023, up from reported revenues of just under $26bn during 2013. 

Since issuing this ambitious growth plan, Astra’s management has admitted that it will be a tough target to hit, but the company has plenty going for it. 

For example, Astra has developed an industry-leading immuno-oncology portfolio with 13 clinical trials already under way. A further 16 trials are planned and a total of 14 potential new drugs are already in the process of Phase III testing or registration before sale. As many as ten drug approvals are set for 2016.

Right now Astra offers a dividend yield of 3.8%, which is similar to the market average of 3.5%. The company’s dividend is nothing to get excited about.

Still, Astra’s dividend is guaranteed for the next few years as management’s compensation is linked to key dividend metrics. In particular, the company’s ‘Azip’ executive compensation plan dictates that the company’s dividend must not be cut and earnings per share must not fall below 1.5 times the dividend. If either of these targets are not met, then management pay benefits are forfeited. 

Dependable dividend 

Compared to Astra, Glaxo does not have a defined growth plan in place but that does not mean that the group is taking things easy. Indeed, Glaxo’s management has signed a flurry of deals over the past few months, which have repositioned the company and put it on a course for steady growth. 

These deals include the asset swap with Novartis and a deal with Aspen Pharmacare Holdings, Africa’s biggest generic drug maker. Additionally, Glaxo is planning to spin off its HIV business set up with Pfizer five years ago, which could attract a valuation of up to £15bn. A selection of prescription medicine brands in Europe and the U.S. with annual sales of around £1bn is also being auctioned off. And finally, the group is planning to cut £1bn of costs over the next three years.

All these deals should reshape Glaxo, infuse the group with cash and put it on a growth footing. What’s more, the company has around 40 new treatments under development at present. These new treatments should only add to the company’s growth. 

Of course, Glaxo’s most attractive quality is its dividend yield. At present levels, the company supports a dividend yield of 5.3%. The payout is covered one-and-a-half times by earnings per share and management has made a commitment to maintaining the payout at current levels. So, for income seekers, Glaxo is a better pick than Astra.

Foolish summary

All in all, it seems as if the best company for growth investors is Astra, while income seekers should look to Glaxo. That being said, it remains to be seen if Astra can actually achieve its target to double revenues over the next few years. A lot rests on this commitment by management. 

Rupert Hargreaves owns shares of GlaxoSmithKline. The Motley Fool UK has recommended GlaxoSmithKline. We Fools don't all hold the same opinions, but we all believe that considering a diverse range of insights makes us better investors.

More on Investing Articles

Investing Articles

Is Alphabet still one of the best shares to buy heading into 2026?

The best time to buy shares is when other investors are seeing risks. Is that the case with Google’s parent…

Read more »

Investing Articles

Could the Barclays share price be the FTSE 100’s big winner in 2026?

With OpenAI and SpaceX considering listing on the stock market, could investment banking revenues push the Barclays share price higher…

Read more »

Investing Articles

Will the Nvidia share price crash in 2026? Here are the risks investors can’t ignore

Is Nvidia’s share price in danger in 2026? Stephen Wright outlines the risks – and why some might not be…

Read more »

Middle-aged white man pulling an aggrieved face while looking at a screen
Growth Shares

I asked ChatGPT how much £10,000 invested in Lloyds shares 5 years ago is worth today? But it wasn’t very helpful…

Although often impressive, artificial intelligence has its flaws. James Beard found this out when he used it to try and…

Read more »

Portrait of pensive bearded senior looking on screen of laptop sitting at table with coffee cup.
Investing Articles

Did ChatGPT give me the best FTSE stocks to buy 1 year ago?

ChatGPT can do lots of great stuff, but is it actually any good at identifying winning stocks from the FTSE…

Read more »

Surprised Black girl holding teddy bear toy on Christmas
Investing Articles

Who will be next year’s FTSE 100 Christmas cracker?

As we approach Christmas 2025, our writer identifies the FTSE 100’s star performer this year. But who will be number…

Read more »

Businessman with tablet, waiting at the train station platform
Investing Articles

I asked ChatGPT for an 8%-yielding passive income portfolio of dividend shares and it said…

Mark Hartley tested artificial intelligence to see if it understood how to build an income portfolio from dividend shares. He…

Read more »

Female student sitting at the steps and using laptop
Investing Articles

How much do you need in an ISA to target £8,333 a month of passive income?

Our writer explores a potential route to earning double what is today considered a comfortable retirement and all tax-free inside…

Read more »