3 Reasons To Dump AstraZeneca plc For GlaxoSmithKline plc

AstraZeneca plc’s (LON: AZN) recent rally has been impressive but it could be time to sell out in favour of GlaxoSmithKline plc (LON: GSK).

| More on:

The content of this article was relevant at the time of publishing. Circumstances change continuously and caution should therefore be exercised when relying upon any content contained within this article.

You’re reading a free article with opinions that may differ from The Motley Fool’s Premium Investing Services. Become a Motley Fool member today to get instant access to our top analyst recommendations, in-depth research, investing resources, and more. Learn More.

One of the FTSE 100’s best performers so far this year has been AstraZeneca (LSE: AZN) (NYSE: AZN.US). Indeed, year to date, AstraZeneca has rallied nearly 10%, surging ahead of its peer GlaxoSmithKline (LSE: GSK) (NYSE: GSK.US), which has only returned 1% during the same period.

However, AstraZeneca’s impressive run, it could be time for investors to take profits. 

Future growth

AstraZeneca has outperformed during the last few months thanks to renewed optimism about experimental mental cancer therapies. In particular, investors have been pleased with early-stage trials of the company’s immuno-oncology treatment, which aims to treat cancer patients by boosting their immune system.

astrazenecaUnfortunately, this cancer therapy is not expected to file for regulatory approval much before 2017, which means that AstraZeneca is likely to lose a significant chuck of the market to rivals during this time. What’s more, AstraZeneca’s’ own management does not believe that the company’s overall sales will return to growth until 2017 and over the next three years sales are going to decline further before they start to mover higher.

In comparison. GlaxoSmithKline’s earnings are sales are expected to remain fairly stable over the next few years as the company cuts costs, brings new treatments to market and buys backs shares. 

Still, unlike GlaxoSmithKline AstraZeneca’s treatment sales to China are still expanding, although this is not enough to offset declining sales in other regions around the world as treatments come off patent.

Pipeline

Biotechnology companies like AstraZeneca rely upon their treatment pipelines to drive future growth and boost earnings. Unfortunately, AstraZeneca’s treatment pipeline lacks that of GlaxoSmithKline and the latter is making solid progress bringing new products to market.

GlaxoSmithKlineFor example, GlaxoSmithKline had five new drugs approved for sales during 2013 and a further 40 are in the process of coming to market. Meanwhile, AstraZeneca does not expect to have any new products file for regulatory approval before 2016.

Actually, GlaxoSmithKline’s pipeline of drugs has been called the ‘best in class’ and ‘sector leading by many analysts, putting the company ahead of many of its larger international peers, such as Johnson & Johnson.

Valuation

As AstraZeneca is not expected to return to growth until 2017, in theory the company should trade at a lower valuation than GlaxoSmithKline, as GlaxoSmithKline’s prospects for growth are more promising. This is not the case. Specifically, at present levels, AstraZeneca is trading at a forward P/E of 15.5 for 2014, while GlaxoSmithKline trades at a forward P/E of 14.6.

What’s more, according to City forecasts GlaxoSmithKline’s current share price means the company is trading at 13.6 times 2015 earnings, while AstraZeneca  is trading at 15.7 times, despite the fact the company’s profits are expected to slide. So, it would appear that GlaxoSmithKline is relatively undervalued compared to AstraZeneca.

Further, GlaxoSmithKline currently offers a dividend yield of 4.8%, forecast to rise to 5.2% during 2015. AstraZeneca only offers a yield of 4.2%, forecast to rise 4.3%. All in all, AstraZeneca’s current premium over GlaxoSmithKline really looks unwarranted. 

Rupert does not own any share mentioned within this article. The Motley Fool has recommended shares in GlaxoSmithKline. 

More on Investing Articles

Investing Articles

This red hot equity fund in my SIPP returned 12.6% in the first 2 months of 2026

This global equity fund is delivering huge returns for Edward Sheldon’s SIPP in 2026, despite all the risks and uncertainty…

Read more »

Friends at the bay near the village of Diabaig on the side of Loch Torridon in Wester Ross, Scotland. They are taking a break from their bike ride to relax and chat. They are laughing together.
Investing Articles

Want to retire richer? Here’s Warren Buffett’s golden rule to build wealth

If you want to build wealth for a richer retirement, then following Warren Buffett’s golden rule might be the best…

Read more »

Black woman using smartphone at home, watching stock charts.
Investing Articles

Get ready for stock market volatility…

As conflict in the Middle East makes share prices fluctuate, what strategies can investors use to try and find opportunities…

Read more »

British Isles on nautical map
Investing Articles

Why the FTSE 100 fell almost 5% this week

Declines in mining shares dragged the FTSE 100 down after a strong start to the year. Is the pullback an…

Read more »

Middle aged businesswoman using laptop while working from home
Investing Articles

How much do you need to invest in US stocks to earn a £2,000 monthly passive income?

Is it possible to target several thousand pounds of passive income each month by buying US growth stocks? Absolutely –…

Read more »

A mature woman help a senior woman out of a car as she takes her to the shops.
Investing Articles

How big does your ISA need to be to earn £1,000 a month in passive income?

Andrew Mackie explains how a long-term ISA strategy can help investors build a chunky £12,000 passive income in less than…

Read more »

Investing Articles

£3,000 buys 64 shares in this passive income gem that’s returned 21% a year for the past 10 years

A savvy investor could have easily outpaced the FTSE 100 over the past decade with a few shares in this…

Read more »

A quiet morning and an empty Victoria Street in Edinburgh's historic Old Town.
Investing Articles

Value stock alert! A FTSE 100 share at a 5-year low with record profits

This once-loved growth stock's down almost 50% in seven months despite the company generating record earnings. Is it now the…

Read more »